Faculty of Medicine: Recent submissions
Now showing items 901-920 of 1992
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Safety and antidiarrheal activity of Priva adhaerens aqueous leaf extract in a murine model
(Journal of Ethnopharmacology, 2014)Ethnopharmacological relevance: Priva adhaerens (Forssk.) Chiov., a wildly growing plant, is reported in central Uganda to be. An effective traditional remedy for diarrhea. The objective of this study was to provide a ... -
Prevalence and factors associated with use of herbal medicine among women attending an infertility clinic in Uganda
(BMC Complementary and Alternative Medicine, 2014)Background: Infertility is a public health problem associated with devastating psychosocial consequences. In countries where infertility care is difficult to access, women turn to herbal medicines to achieve parenthood. ... -
Prevalence and Factors Associated With Adverse Drug Events Among Patients On Dolutegravir-Based Regimen At The Immune Suppression Syndrome Clinic of Mbarara Regional Referral Hospital, Uganda: A Retrospective Cross-Sectional Study.
(Research square, 2022)Background: Highly Active Antiretroviral Therapy is efficacious in suppression of Human Immunodeficiency Virus (HIV) however; it is associated with numerous toxicities hence great effort has been put into development of ... -
Predictors of hospital‑acquired adverse drug reactions: a cohort of Ugandan older adults
(BMC Geriatrics, 2022)Background: Globally, it is estimated that the number of older adults will become 2 billion by 2050. The identification of the predictors of adverse drug reaction (ADR) in hospitalized older patients is crucial to the ... -
Plants used to treat malaria in Nyakayojo sub-county, western Uganda
(Journal of Ethnopharmacology, 2011)Aim of study: We performed an ethnobotanical study of plants used to treat malaria in Nyakayojo subcounty in south western Uganda because malaria in this region, and in Uganda at large, is still the single most important ... -
Phytochemical Analysis, Acute Toxicity, as well as Antihyperglycemic and Antidiabetic Activities of Corchorus olitorius L. Leaf Extracts
(The Scientific World Journal, 2022)Background and Aim: Diabetes mellitus is a metabolic disorder that has no known cure with continuous endeavors to find a therapy for the condition. According to some studies, traditional leafy vegetables could prevent and ... -
Off‑label antibiotic use among paediatric in‑patients: a mixed‑method prospective study at a tertiary hospital in southwestern Uganda
(International Journal of Clinical Pharmacy, 2020)Background: The off-label use of drugs to treat children is a global practice attributed to the traditional exclusion of children from clinical trials mainly due to practical and ethical reasons. Off-label drug use carries ... -
Influence of hormonal status on behavioral responses to an acute ethanol challenge during ethanol withdrawal in male and female rats
(Pharmacology, Biochemistry and Behavior, 2008)We previously reported significant sex differences in ethanol withdrawal (EW) recovery as well as in sensitivity to GABAA receptor modulators during EW. The aim of the present study was to determine if hormonal status ... -
Evaluation of the Acute and Sub chronic Toxicities of the Methanolic Stem Bark Extract of Spathodea campanulata (P. Beauv.) Bignoniaceae
(British Journal of Pharmacology and Toxicology, 2015)Spathodea campanulata (P. Beauv.) Bignoniacea is widely used in Ugandan traditional medicine without having much knowledge on any toxicity data. This study carried out the toxicity profile of its methanolic stem bark extract ... -
Chronic wound isolates and their minimum inhibitory concentrations against third generation cephalosporins at a tertiary hospital in Uganda
(Scientific Reports, 2022)Globally, the burden of chronic wound infections is likely to increase due to the rising levels of bacterial resistance to antibiotics. In the United States of America alone, more than 6.5 million chronicwounds with evidence ... -
Association of testosterone levels with socio-demographic characteristics in a sample of Ugandan men
(African Health Sciences, 2014)Background: Testosterone, a male reproductive hormone, affects several physiological processes, such as sperm production, energy, strength, sexual behavior, sleep and the general wellbeing of men. Normal levels of testosterone ... -
Assessment of the immunomodulatory activity of Artavol® aqueous extract in Plasmodium berghei infected mice
(African Journal of Pharmacy and Pharmacology, 2022)ARTAVOL® is an herbal product derived from de-artemisinised extracts of Artemisia annua combined with lemon grass extract and avocado seed powder as a base locally used in Uganda for malaria prevention. This study assessed ... -
Antifungal Activity of the Essential Oil of Echinops kebericho Mesfin: An In Vitro Study
(Evidence-Based Complementary and Alternative Medicine, 2020)Background: Echinops kebericho is an endemic medicinal plant in Ethiopia widely used in the treatment of infectious and noninfectious diseases. Essential oils are known for their antibacterial, antifungal, antiviral, ... -
Analgesic, anti-inflammatory and oxytocic activities of Dracaena steudneri Engl. stem bark aqueous extract in Wistar rats
(Journal of Medicinal Plants Research, 2022-04)Dracaena steudneri Engl. (Dracaenaceae) is a medicinal plant that is used in labour by traditional birth attendants to induce labour, relieve pain and treat various diseases; albeit no documentation. This study determined ... -
Hypoglycemic, Antihyperglycemic, and Toxic Effects of Physalis peruviana L. Aqueous and Methanolic Leaf Extracts in Wistar Rats
(Journal of Experimental Pharmacology, 2022)Background: Physalis peruviana L. (Solanaceae) is a plant widely used in traditional medicine systems to manage various diseases, including diabetes mellitus, which remains a global health problem in developing and developed ... -
Expression of cFos and brain‑derived neurotrophic factor in cortex and hippocampus of ethanol‑withdrawn male and female rats
(Journal of Pharmacology and Pharmacotherapeutics, 2013)Objective: To map areas of brain activation (cFos) alongside changes in levels of brain-derived neurotrophic factor (BDNF) to provide insights into neuronal mechanisms contributing to previously observed sex differences ... -
What is a good PhD program in ophthalmology?: Students’ perspective
(Journal of Ophthalmology of Eastern Central and Southern Africa, 2018-12)Access to doctoral studies is increasing and the impact of PhD programs is generally understood to be positive. However, the lack of clarity about what a PhD entails can be a barrier to student entry into the programs. ... -
Traditional eye medicine use in microbial keratitis in Uganda: a mixed methods study
(Wellcome Open Research, 2019)Background: Traditional eye medicine (TEM) is frequently used to treat microbial keratitis (MK) in many parts of Africa. Few reports have suggested that this is associated with a worse outcome. We undertook this large ... -
Thinness among children aged 5- 17 years living in Nakivale refugee settlement, South Western Uganda: A Cross-sectional study
(Research square, 2022-04-04)Background: Hunger and malnutrition are rampant among refugees and displaced populations, many of whom are infants and children. We sought to determine the prevalence and factors associated with thinness among children ... -
The Lancet Global Health Commission on Global Eye Health: vision beyond 2020
(The Lancet Global Health Commission, 2021)Eye health and vision have widespread and profound implications for many aspects of life, health, sustainable development, and the economy. Yet nowadays, many people, families, and populations continue to suffer the ...