Mbarara University of Science and Technology Institutional Repository: Recent submissions
Now showing items 141-160 of 3211
-
Models to predict expansive intracranial hematomas occurrence for adult traumatic brain injury patients presenting at Accident and Emergency Department at Mulago National referral Hospital in Uganda
(Journal of Global Neurosurgery, 2024)Background: A timely and accurate surgical decision regarding expansive intracranial hematomas (EIH) is crucial in clinical practice and patient outcomes, particularly in resource-limited settings. Although several predictive ... -
Diagnostic Utility of GeneXpert MTB/RIF Assay in EPTB Detection in Formalin Fixed Paraffin Embedded Tissue Biopsies in South Western Uganda
(Pathology and Laboratory Medicine International, 2024)Purpose: Formalin-fixed tissue biopsies submitted to the Histopathology Laboratory were explored for possible use in the GeneXpert MTB/Rifampicin assay for EPTB diagnosis, therefore this study aimed to determine the ... -
Death after cure: Mortality among pulmonary tuberculosis survivors in rural Uganda
(International Journal of Infectious Diseases, 2024)Objectives: To determine the incidence of mortality and its predictors among pulmonary tuberculosis (PTB) survivors treated at a rural Ugandan tertiary hospital. Methods: We conducted a retrospective chart review of data ... -
Filicide in Africa: a systematic review
(BMC Public Health, 2024)Background: Filicide, the act of a parent or parental figure killing their child, has been reported in various African countries. However, there is a lack of comprehensive reviews on the prevalence and associated factors ... -
Effect of metabolic syndrome and its components on the risk and prognosis of cervical cancer: A literature review
(Gynecologic Oncology Reports, 2024)Despite the global implementation of preventive strategies against Human Papilloma Virus (HPV) infection, the incidence of invasive cervical cancer rose by nearly 1.3-fold, from 471,000 annual cases in 2000 to 604,000 cases ... -
A Mathematical Model for the Dynamics of Onchocerciasis With Vector Control and Mass Drug Administration
(Journal of Applied Mathematics, 2024)In this paper, we investigate the transmission dynamics of onchocerciasis with asymptomatic infected humans using a mathematical model. The model incorporates interventions for treatment and vector control to evaluate the ... -
Effectiveness of Jena DM® Herbal Formulation as Complementary Therapy to Conventional Oral Hypoglycemic Agents in Type-2 Diabetes Mellitus: A Quasi-Experimental Study
(Cureus, 2024)Background: There is vast preclinical evidence that indicates that extracts from several Artemisia plant species have significant antidiabetic benefits. However, clinical evidence is limited to this effect. Objective: We ... -
A Comparison Analysis on Remdesivir, Favipiravir, Hydroxychloroquine, Chloroquine and Azithromycin in the Treatment of Corona Virus Disease 2019 (Covid-19) - A Review
(World Journal of Pharmacy and Pharmaceutical Sciences, 2020)Background: This comparative study is to ascertain the efficacy and results proven drug used in the management of the novel corona virus disease 19 since most patients admitted are recovering while there is no clinically ... -
Coping strategies, challenges and potential interventions among adult patients with HIV and mental illness comorbidity in southwestern Uganda
(Global Public Health, 2024)HIV and mental illness comorbidity presents significant healthcare challenges, especially in low- and middle-income countries where healthcare systems often address individual conditions rather than comorbidities. This ... -
Closure of Schools During Covid-19 Pandemic- an Assessment of Learning Interventions by Governments on Limiting Disruptions of Education Programme- a Case of Uganda
(International Journal of Social Sciences and Management Review, 2022)This study is about the Closure of Schools during the Covid-19 Pandemic: An Assessment of Learning Interventions by Governments on Limiting Disruptions of Education Programmes The study focused on “how effective and efficient ... -
Carbapenem‑resistant Enterobacteriaceae in the livestock, humans and environmental samples around the globe: a systematic review and meta‑analysis
(Scientific Reports, 2024)Carbapenem‑resistant Enterobacteriaceae (CRE) have diminished treatment options causing serious morbidities and mortalities. This systematic review and meta‑analysis assessed the prevalence and associated factors of ... -
Association between dyslipidemia and cervical intraepithelial neoplasia: A case-control study in south-western Uganda
(African Journal of Laboratory Medicine, 2024)Background: Altered lipid levels may be associated with the development of a number of malignancies, including cancer of the cervix. However, there is limited understanding of this relationship in the rural Ugandan context. ... -
Gut-brain axis: A cutting-edge approach to target neurological disorders and potential synbiotic application
(Heliyon, 2024)The microbiota-gut-brain axis (MGBA) represents a sophisticated communication network between the brain and the gut, involving immunological, endocrinological, and neural mediators. This bidirectional interaction is ... -
Dominance and rarity in tree communities across the globe: Patterns, predictors and threats
(Global Ecology and Biogeography, 2024-06-23)Aim: Ecological and anthropogenic factors shift the abundances of dominant and rare tree species within local forest communities, thus affecting species composition and ecosystem functioning. To inform forest and conservation ... -
Evidence of thermophilization in Afromontane forests
(Nature communications, 2024-07-10)Thermophilization is the directional change in species community composition towards greater relative abundances of species associated with warmer environments. This process is well-documented in temperate and Neotropical ... -
Point-of-care potentials of lateral flow-based field screening for Mycoplasma bovis infections: a literature review
(Biology Methods and Protocols, 2024)Point-of-care (POC) field screening for tools for Mycoplasma bovis (M. bovis) is still lacking due to the requirement for a simple, robust field-applicable test that does not entail specialized laboratory equipment. In ... -
Primary Healthcare Workers’ Awareness of Acute Rheumatic Fever & Rheumatic Heart Disease: A Study in Public Health Facilities in South Western Uganda
(Pediatric Health, Medicine and Therapeutics, 2024)Introduction: Timely identification and treatment of a streptococcal throat infection prevents acute rheumatic fever (ARF) and its progression to Rheumatic Heart Disease (RHD). However, children in developing countries ... -
Sequence variation does not confound the measurement of plasma PfHRP2 concentration in African children presenting with severe malaria
(Malaria journal, 2012)Background: Plasmodium falciparum histidine-rich protein PFHRP2 measurement is used widely for diagnosis, and more recently for severity assessment in falciparum malaria. The Pfhrp2 gene is highly polymorphic, with deletion ... -
Evaluation of OMNIgene Sputum and Ethanol Reagent for Preservation of Sputum Prior to Xpert and Culture Testing in Uganda
(Journal of Clinical Microbiology, 2019)Xpert MTB/RIF (Xpert) and culture are the most reliable methods for tuberculosis diagnosis but are still poorly accessible in many low-resource countries. We aimed to assess the effects of OMNIgene Sputum (OM-S) and ethanol ... -
Effect of Empiric Anti–Mycobacterium tuberculosis Therapy on Survival Among Human Immunodeficiency Virus–Infected Adults Admitted With Sepsis to a Regional Referral Hospital in Uganda
(In Open Forum Infectious Diseases, 2019)Background: Mycobacterium tuberculosis is the leading cause of bloodstream infection among human immunodeficiency virus (HIV)–infected patients with sepsis in sub-Saharan Africa and is associated with high mortality ...