Mbarara University of Science and Technology Institutional Repository: Recent submissions
Now showing items 461-480 of 3211
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Hepatitis B virus infection and HBeAg positivity among pregnant women in South West Uganda
(African Journal of Laboratory Medicine, 2022)Background: Hepatitis B virus is a public health burden in Uganda, yet little is known about its epidemiology in pregnancy. Objective: This study aimed at determining the prevalence and associated risk factors of hepatitis ... -
Efficacy of extended focused assessment with sonography for trauma using a portable handheld device for detecting hemothorax in a low resource setting; a multicenter longitudinal study
(BMC Medical Imaging, 2022)Introduction: Chest trauma is one of the most important and commonest injuries that require timely diagnosis, accounting for 25–50% of trauma related deaths globally. Although CT scan is the gold standard for detection of ... -
Development and Validation of ‘Prediction of Adverse Drug Reactions in Older Inpatients (PADROI)’ Risk Assessment Tool
(Clinical Interventions in Aging, 2022)Background: Adverse drug reactions (ADR) detection and prediction methods in hospitalized older adults remain imprecise. The identification of the risk factors for ADRs in this group of patients is crucial to develop ... -
Prevalence and factors associated with adverse drug reactions among heart failure patients hospitalized at Mbarara Regional Referral Hospital, Ugand
(BMC Cardiovascular Disorders, 2022)Background: Adverse drug reaction (ADR) of medications remains an obstacle to achieving optimal disease outcomes. This study aimed to assess the prevalence and associated factors of ADR among Heart failure (HF) patients ... -
From Toxins to Drugs: Chemistry and Pharmacology of Animal Venom and other Secretions
(Online Journal of Complementary & Alternative Medicine, 2019)Animal secretions are currently proving more than before to be one of the best sources of drugs for current and future health complications. Well managed and optimized, their chemical compounds can as well be used to prevent ... -
African Progress in Drug Development Chemistry; a 100 Years Update
(2018)Africa is currently very active in the search for drugs particularly with focus on the preclinical phases of drug discovery. This work aimed at determining the extent to which Africa has gone with research and studies in ... -
An Ethics-based Approach to Global Health Research Part 2: Strategies for Overcoming Logistic and Implementation Challenges
(Research in Social and Administrative Pharmacy, 2020)With the growth of global pharmacy partnerships and collaborative research, particularly between high-income countries and low- or middle-income countries, it is necessary to establish best practices for fair and ethical ... -
Frogs and Lizards as Potential Drug Sources- a Mini Review
(Current Trends in Complementary and Alternative Medicine, 2018)Today, the world is heavily weighed down by emerging health complications which are exacerbated by the emergency of Multi Drug Resistant (MDR) microorganisms. This is happening despite the search for new and better drugs ... -
Toxicity Protocols for Natural Products in the Drug Development Process
(Poisonous Plants and Phytochemicals in Drug Discovery, 2020)Natural products are less toxic than synthetic compounds because of the adaption of humans and animals through exposure over time, which has enabled them to develop detoxification mechanisms [1]. Phytochemicals are extracted ... -
Chemical and Pharmacological Mechanisms of Plant-Derived Neurotoxins
(Poisonous Plants and Phytochemicals in Drug Discovery, 2020)The nervous system (NS) comprises the central and peripheral divisions. While the central nervous system (CNS) consists mainly of the brain and spinal cord, the peripheral nervous system (PNS) is subdivided into the somatic ... -
Predominance of multidrug-resistant bacteria causing urinary tract infections among symptomatic patients in East Africa: a call for action
(JAC-Antimicrobial Resistance, 2024)Background: In low- and middle-income countries, antibiotics are often prescribed for patients with symptoms of urinary tract infections (UTIs) without microbiological confirmation. Inappropriate antibiotic use can contribute ... -
High Levels of Fungal and Aflatoxin Contamination of the Production Stages of the Local Brew (Ajono) consumed in Uganda
(East African Journal of Health and Science, 2024)Local brew commonly known as Ajono is a widely consumed alcoholic beverage in Uganda. Handling practices along the production stages of the local brews may create a conducive environment for fungal colonization. This study ... -
HIV, Social Networks, and Loneliness among Older Adults in Uganda
(AIDS and Behavior, 2024)Loneliness among older adults has been identified as a major public health problem. Yet little is known about loneliness, or the potential role of social networks in explaining loneliness, among older people with HIV (PWH) ... -
A practical tool for managing change: crosssectional psychometric assessment of the safe surgery organizational readiness tool
(International Journal of Surgery, 2024)Background: Strengthening health systems through planned safety and quality improvement initiatives is an imperative to achieve more equitable, resilient, and effective care. And yet, years of organizational behavior ... -
Treatment seeking behaviours, antibiotic use and relationships to multi-drug resistance: A study of urinary tract infection patients in Kenya, Tanzania and Uganda
(PLOS Global Public Health, 2024)Antibacterial resistance (ABR) is a major public health threat. An important accelerating factor is treatment-seeking behaviour, including inappropriate antibiotic (AB) use. In many low and middle-income countries (LMICs) ... -
The Impact of the Gut Microbiome, Environment, and Diet in Early-Onset Colorectal Cancer Development
(Cancers, 2024)Traditionally considered a disease common in the older population, colorectal cancer is increasing in incidence among younger demographics. Evidence suggests that population land generational-level shifts in the composition ... -
Predictors for the utilization of community support systems against intimate partner violence among married women living with HIV in southwestern Uganda—A cross sectional study
(Plos one, 2024)Background: Intimate partner violence (IPV) disproportionately affects married women living with HIV (MWLHIV), resulting in undesirable human rights, socio-economic, mental, maternal, and child health consequences. Community ... -
Impact of Intrinsic Motivational Practices on Performance in Secondary School Teachers: A Cross-sectional Study in Mbarara City, Uganda
(Asian Education, 2024)Performance of secondary school teachers is sequential to intrinsic motivational practices, particularly among teachers experiencing financial strain across global in various contextual settings. This study investigated ... -
HRP2 and PLDH Performance Comparison as Rapid Diagnostic Tools for Symptomatic Malaria Patients at Rugazi HC IV in Rubirizi District
(International Internal Medicine Journal, 2024-02-13)Background: Rapid and precise laboratory diagnosis is essential for effectively diagnosing and managing malaria patients. Malaria rapid diagnostic tests (mRDTs) play a critical role in malaria diagnosis in resource-constrained ... -
Relationship between students’ attitude towards, and performance in mathematics word problems
(Plos one, 2024)The study explored the relationship between students’ attitude towards, and performance in mathematics word problems (MWTs), mediated by the active learning heuristic problem solving (ALHPS) approach. Specifically, this ...