Browsing Department of Pharmacy by Title
Now showing items 1-20 of 197
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Acute and repeated-dose toxicity of Echinops kebericho Mesfin essential oil
(Toxicology Reports, 2021)Echinops kebericho Mesfin is used for the management of various diseases and fumigation during child birth. This study investigated acute and repeated-dose toxicity of E. kebericho M. essential oils (EOs). The study was ... -
Acute and Sub-acute Toxicity Evaluation in Rats of PPOJ5 and ADOJ6 Herbal Remedies Used Traditionally in the Management of HIV Infection
(European Journal of Medicinal Plants, 2016-09-27)The use of herbal medicine in the treatment of many ailments is on the rise. It’s a common practice in many rural communities where access to health care is poor but also in the developed world. There is however, no much ... -
Acute and sub-acute oral toxicity of aqueous whole leaf and green rind extracts of Aloe vera in Wistar rats
(BMC complementary medicine and therapies, 2022)Background: Several local communities in Central, Western, Eastern, and Northern regions of Uganda have been using the whole leaf extracts of Aloe vera (L.) Burm. f. (Asphodelaceae) in the treatment of various ailments. ... -
Acute toxicity, antipyretic and antinociceptive study of the crude saponin from an edible vegetable
(Int. J. Biol. Chem. Sci., 2012)Vernonia amygdalina is commonly used for food and health purposes. Processing of the leaf for food is aimed at removing bitter tasting antinutritional principles like saponins. This study was designed to determine the ... -
ADMET profiling and molecular docking of potential antimicrobial peptides previously isolated from African catfish, Clarias gariepinus
(Frontiers in Molecular Biosciences, 2022)Amidst rising cases of antimicrobial resistance, antimicrobial peptides (AMPs) are regarded as a promising alternative to traditional antibiotics. Even so, poor pharmacokinetic profiles of certain AMPs impede their utility ... -
Adverse drug reaction reporting among health care workers at Mulago National Referral and Teaching hospital in Uganda
(African Health Sciences, 2015)Background: Adverse Drug Reactions (ADRs) are an important contributor to patient morbidity and hospitalisation in Uganda. Under-reporting of ADRs may increase medicine-induced morbidity and mortality among patients. This ... -
Aflatoxins metabolism, effects on epigenetic mechanisms and their role in carcinogenesis
(SciRes, 2013)Chronic consumption of aflatoxin-contaminated foods is a global problem in both developing and developed countries especially where there is poor regulation of their levels in foods. In the body, aflatoxins (AFBs) mainly ... -
African Journal of Pharmacy and Pharmacology Phytochemical and efficacy study on four herbs used in erectile dysfunction: Mondia whiteii, Cola acuminata, Urtica massaica, and Tarenna graveolens
(African Journal of Pharmacy and Pharmacology, 2016-10-10)here is a resurgence in the use of herbal medicine in the developed countries, with even much more in low developed Countries and especially for conditions such as erectile dysfunction. Studies thus need to be conducted ... -
Analgesic Appraisal of Bidens pilosa (Asteraceae) Leaf Extracts Used in Management of Oral Lesion Pain in HIV/AIDS Patients in Rodents
(Pharmacology & Pharmacy, 2018)Oral lesions, diarrhoea, Pneumocystis carinii pneumonia, tuberculosis and urinary tract infections are some of the opportunistic infections (OIs) which arise when the CD4 cells of the HIV/AIDS patient fall below 200 ... -
Anti-ageing Activity and Antioxidant Activity of Methanol Extracts of Leaves and Flowers of Salvia officinalis and Rosmarinus officinalis
(Journal of Young Pharmacists, 2023)Background: In this present work, methanol extracts of the leaves and flowers of Salvia officinalis Linn. (MES) and Rosmarinus officinalis Linn. (MER) were examined for their potential anti-aging and antioxidant properties ... -
Antibacterial prescription and the associated factors among outpatients diagnosed with respiratory tract infections in Mbarara Municipality, Uganda
(BMC Pulmonary Medicine, 2021-11-15)Background: Respiratory tract infections (RTI) are the second most frequent diagnosis after Malaria amongst Outpatients in Uganda. Majority are Non pneumonia cough and flu which are self-limiting and often do not require ... -
Anticancer potential of delphinidin and its derivatives: therapeutic and mechanistic insights
(Medicinal Chemistry Research, 2024)Anthocyanins are water-soluble naturally occurring flavonoids present in fruits, flowers, leaves, and roots of fruit plants and vegetables. One of the important anthocyanidin components of red wine and berries is delphinidin ... -
Anticonvulsant and anxiolytic activity of the leaf aqueous and ethanolic extracts of Melanthera scandens in a rat model
(HHS Public Access, 2016)Modern drug therapy of epilepsy is complicated by the inability of drugs to control seizures in some patients and side effects that range in severity from minimal impairment of the central nervous system to death from ... -
Antidiabetic Medicinal Plants Used in Democratic Republic of Congo: A Critical Review of Ethnopharmacology and Bioactivity Data
(Frontiers in Pharmacology, 2021-10-27)Several studies have been conducted and published on medicinal plants used to manage Diabetes Mellitus worldwide. It is of great interest to review available studies from a country or a region to resort to similarities/d ... -
Antifungal activity of Cleome gynandra L. aerial parts for topical treatment of Tinea capitis: an in vitro evaluation
(Complementary and Alternative Medicine, 2016-07)Background: Cleome gynandra L. (Capparaceae) is an edible weed used in Uganda topically for its presumed antifungal activity against Tinea capitis. The goal of this study was to determine if this plant possesses antifungal ... -
Antimicrobial resistance and rational prescription practices: knowledge, perceptions and confidence of health profession interns in Uganda
(JAC-Antimicrobial Resistance, 2023)Background: Antimicrobial resistance (AMR) is significantly driven by misuse and overuse of antibiotics. Graduate health profession interns often prescribe antimicrobials under minimum supervision. Objectives: This study ... -
Antipyretic and Antinociceptive Properties of the Aqueous Extract and Saponin from an Edible Vegetable- Vernonia Amygdalina Leaf
(African Journal of food, agriculture, nutrition and development, 2013)Vernonia amygdalina is commonly used for food and health purposes. The processing of the leaf for food is usually aimed at removing bitter tasting principles like saponins. This study was designed to determine the antipyretic ... -
Antisickling effect of crude flavonoids in the methanolic leaf extract of Persea americana Mill
(Revista Cubana de Plantas Medicinales, 2019-06)Introduction: Sickle-cell anemia, a difficult-to-treat genetic disease, causes synthesis of abnormal hemoglobin in which erythrocytes assume a sickle shape and become susceptible to hemolysis. Research about Persea americana ... -
Appetite Suppressing Activity of Rumex Usambarensis Leaf and Stem Aqueous Extract in Wistar Albino Female Rats: an in vivo Experimental Study
(Journal of Experimental Pharmacology, 2024)Background: The burden of obesity and overweight associated morbidity and mortality is increasing in epidemic proportions worldwide. Suppression of appetite is one of the mechanisms that has been shown to reduce weight. ... -
Appetite Suppressing Activity of Rumex Usambarensis Leaf and Stem Aqueous Extract in Wistar Albino Female Rats: an in vivo Experimental Study
(Journal of Experimental Pharmacology, 2024)Background: The burden of obesity and overweight associated morbidity and mortality is increasing in epidemic proportions worldwide. Suppression of appetite is one of the mechanisms that has been shown to reduce weight. ...
