Department of Pharmacy: Recent submissions
Now showing items 61-80 of 188
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High PrEP uptake and objective longitudinal adherence among HIV-exposed women with personal or partner plans for pregnancy in rural Uganda: A cohort study
(PLoS Medicine, 2023)Background: In Uganda, fertility rates and adult HIV prevalence are high, and many women conceive with partners living with HIV. Pre-exposure prophylaxis (PrEP) reduces HIV acquisition for women and, therefore, infants. ... -
Body composition of type 2 diabetes patients in Uganda: A case-control study
(Journal of public health in Africa, 2023)Introduction: The prevalence of obesity among people diagnosed with Type 2 Diabetes Mellitus (T2DM) has been widely documented. However, the specific composition of this bodyweight remains largely unknown. The study aimed ... -
Diversity of bacterial community in the rhizosphere and bulk soil of Artemisia annua grown in highlands of Uganda
(Plos one, 2023)High land areas in Uganda are suitable for the farming of Artemisia annua. However, harvested A. annua from these areas contain varying concentrations of antimalarial components. This may be attributed to variation in soil ... -
Comparison of the Wound Healing Activity of the Leaf and Leaf Ash Extracts of Vernonia amygdalina in Rats
(Research square, 2023)Background: Species in the genus Vernonia (Asteraceae) are traditionally used in the treatment of different ailments, for example, leaves in both fresh and dry forms have been used in dressing wounds. Anecdotal reports ... -
Evaluating the Feasibility, Acceptability, and Preliminary Efficacy of SupportMoms-Uganda, an mHealth-Based Patient-Centered Social Support Intervention to Improve the Use of Maternity Services Among Pregnant Women in Rural Southwestern Uganda: Randomized Controlled Trial
(JMIR Formative Research, 2023)Background: SMS text messaging and other mobile health (mHealth) interventions may improve knowledge transfer, strengthen access to social support (SS), and promote positive health behaviors among women in the perinatal ... -
Ethnobotanical Survey of Medicinal Plants Used in Breast Cancer Treatment by Traditional Health Practitioners in Central Uganda
(Journal of Multidisciplinary Healthcare, 2023)Purpose: The study aimed to document the existing knowledge and practices related to breast cancer recognition and treatment using medicinal plants by traditional health practitioners in Central Uganda. Methods: This ... -
Review of Deforestation in Ugandan Tropical Rainforest Reserves: A Threat to Natural Medicine
(East African Journal of Environment and Natural Resources, 2022)Deforestation in Ugandan Tropical Rainforest Reserves as threat to natural medicine is still undocumented. In this study, we reviewed literature on deforestation most especially from 1990-2020 in the Tropical Rainforest ... -
In-vitro antihelminthic activity of alcoholic extract from Paullinia pinnata Linn against Ascaris suum
(Revista Cubana de Plantas Medicinales, 2018)Introduction: Medicinal plants are used both for the treatment of certain conditions and to preserve health and vitality. According to estimates by the World Health Organization, 80% of the world population, excluding ... -
Identification of Antimicrobial Peptides Isolated From the Skin Mucus of African Catfish, Clarias gariepinus (Burchell, 1822)
(Frontiers in microbiology, 2021)Antimicrobial peptides (AMPs) constitute a broad range of bioactive compounds in diverse organisms, including fish. They are effector molecules for the innate immune response, against pathogens, tissue damage and infections. ... -
Evaluation of Cafeteria Diet in Experimental Animal with Plant Extract of Calotropis procera for Obesity Parameter
(Journal for Research in Applied Sciences and Biotechnology, 2022)The function of obesity in an insulin-resistant syndrome associated with hyper insulinemia, hypertension, hyperlipidemia, atherosclerotic diseased illness is vital. Hunger, body weight and lipid profile investigations thus ... -
Traditional Approaches and Medicinal Plants in Treatment of Epilepsy in West and East Africa
(NeuroPharmac Journal, 2020)Background: Epilepsy has affected over sixty million people around the globe. Traditionally, communities have opted for complementary and alternative medicines (CAM) to help in the treatment of epilepsy which has worked ... -
Pharmacognostic and phytochemical studies as an invaluable approach for correct identification of medicinal plants: The case of Artemisia vulgaris L. substituted for Artemisia annua L. in Western Uganda
(TMR Integrative Medicine, 2023)Different parts of Artemisia vulgaris L. (A. vulgaris) are ethno-medicinally used as an emmenagogue and for the treatment of ailments such as malaria fever, ulcers, and cancer. However, anecdotal evidence shows that the ... -
ADMET profiling and molecular docking of potential antimicrobial peptides previously isolated from African catfish, Clarias gariepinus
(Frontiers in Molecular Biosciences, 2022)Amidst rising cases of antimicrobial resistance, antimicrobial peptides (AMPs) are regarded as a promising alternative to traditional antibiotics. Even so, poor pharmacokinetic profiles of certain AMPs impede their utility ... -
Retrospective in silico mutation profiling of SARS-CoV-2 structural proteins circulating in Uganda by July 2021: Towards refinement of COVID-19 disease vaccines, diagnostics, and therapeutics
(Plos one, 2022)The SARS-CoV-2 virus, the agent of COVID-19, caused unprecedented loss of lives and economic decline worldwide. Although the introduction of public health measures, vaccines, diagnostics, and therapeutics disrupted the ... -
SARS-CoV-2 vaccine development
(Coronavirus Drug Discovery, 2022)Vaccine development is the entire process involved in the designing of a vaccine to the post release study period. Vaccines work against viruses, bacteria, fungi and parasites. The design in which an antiviral vaccine is ... -
Effect of Covid-19 in Management of Lung Cancer Disease: A Review
(Asian Journal of Pharmaceutical Research and Development, 2022)COVID-19 outcomes may be more severe in lung cancer patients. As a COVID-19 pandemic spreads, it's critical to identify which people and malignancies are most susceptible. COVID-19 appears to have the worst results in lung ... -
Potentially harmful medication use and the associated factors among pregnant women visiting antenatal care clinics in Mbarara Regional Referral Hospital, Southwestern Uganda
(Journal of Clinical and Translational Research, 2023)Background: Pregnancy management using medications has been challenging for both healthcare providers and pregnant women, given the fear of teratogenicity effects and the potential for fetal harm. In the developing world, ... -
Association between Pre-Hospital Antibiotic Exposure and Level of Bacterial Resistance (PHAE Study): A Matched Case Control Study at the Medical and Paediatric wards of Mbarara Regional Referral Hospital-South Western Uganda
(Research square, 2022-09-07)Background: This study aimed to determine the association between pre-hospital antibiotic exposure and level of bacterial resistance among adult and paediatric patients. Methods: In the study, 79 antibiotic pre-exposed ... -
Ligand-protein interactions of plant-isolated (9z,12z)-octadeca-9,12-dienoic acid with B-ketoacyl-Acp synthase (KasA) in potential anti-tubercular drug designing
(Scientific African, 2021)Mycobacterium tuberculosis remains one of the world’s contributors to mortality. With the emergence of SARS-CoV-2 coinfections, patients with TB are predisposed to being more heavily weighed down by COVID-19 disease and ... -
Therapeutic potentials of Vachellia nilotica (L.) extracts in Hepatitis C infection: A review
(Scientific African, 2021)Hepatitis C Virus (HCV) infection represents a huge burden on healthcare systems world- wide. Vachellia nilotica ( V. nilotica ) is a widely used plant specie in folk medicine for viral diseases and in some communities for ...