Browsing Research Articles by Subject "Adherence"
Now showing items 1-9 of 9
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Adherence to HIV antiretroviral therapy among pregnant and postpartum women during the Option B+ era: 12-month cohort study in urban South Africa and rural Uganda
(Journal of the International AIDS Society, 2020)Introduction: We conducted a cohort study to understand patterns of anti-retroviral therapy (ART) adherence during pregnancy, postpartum and non-pregnancy follow-up among women initiating ART in public clinics offering ... -
Antiretroviral Therapy Adherence Interruptions are Associated with Systemic Inflammation among Ugandans who Achieved Viral Suppression
(Journal of acquired immune deficiency syndromes, 2019)Background: Residual systemic inflammation, which is associated with non-AIDS clinical outcomes, may persist despite viral suppression. We assessed the effect of antiretroviral (ART) adherence interruptions on systemic ... -
Higher ART Adherence is Associated with Lower Systemic Inflammation in Treatment-naïve Ugandans who Achieve Virologic Suppression
(Journal of acquired immune deficiency syndromes, 2018)Background: Residual systemic inflammation persists despite suppressive antiretroviral therapy (ART) and is associated with non-AIDS clinical outcomes. We aimed to evaluate the association between ART adherence and ... -
Higher baseline CD4 cell count predicts treatment interruptions and persistent viremia in patients initiating ARVs in rural Uganda
(Journal of acquired immune deficiency syndromes, 2013)We examined the association between CD4 cell count and adherence in a cohort of Ugandans initiating ARVs. Outcomes were: a) adherence<90%; b) any treatment interruptions>72 hours; c) number of treatment interruptions; and ... -
Perceived barriers and facilitators to antiretroviral therapy adherence among youth aged 15-24 years at a regional HIV clinic in SouthWestern Uganda: a qualitative study
(African Health Sciences, 2022)Introduction: South-Western region has the second highest HIV prevalence in Uganda. Youth aged 15-24 have shown poor adherence to antiretroviral therapy compared to the older cohorts. Previous studies from other regions ... -
Real-time electronic adherence monitoring plus follow-up improves adherence compared to standard electronic adherence monitoring
(AIDS, 2017-01)The impact of real-time electronic monitoring on antiretroviral therapy adherence warrants further study. We conducted an analysis of cohort participants that initially involved standard electronic adherence monitoring ... -
Super learner analysis of real-time electronically monitored adherence to antiretroviral therapy under constrained optimization and comparison to non-differentiated care approaches for persons living with HIV in rural Uganda
(Journal of the International AIDS Society, 2020)Introduction: Real-time electronic adherence monitoring (EAM) systems could inform on-going risk assessment for HIV viraemia and be used to personalize viral load testing schedules. We evaluated the potential of real-time ... -
Unhealthy Alcohol Use Is Associated With Suboptimal Adherence to Isoniazid Preventive Therapy in Persons With HIV in Southwestern Ugand
(JAIDS Journal of Acquired Immune Deficiency Syndromes, 2022)Background: Unhealthy alcohol use is associated with increased progression to tuberculosis (TB) disease, but its effect on adherence to isoniazid (INH) preventive therapy is not known. Methods: This was a prospective ... -
Validity and Reliability of a Self-Reported Measure of Antihypertensive Medication Adherence in Uganda
(PLoS ONE, 2016-07-01)Background: The Morisky Medication Adherence scale (MMAS-8) is a widely used self-reported measure of adherence to antihypertensive medications that has not been validated in hypertensive patients in sub-Saharan ...
