dc.contributor.author | Obayo, Siraji | |
dc.contributor.author | Muzoora, Conrad | |
dc.contributor.author | Ocama, Ponsiano | |
dc.contributor.author | Cooney, Matthew M. | |
dc.contributor.author | Wilson, Tony | |
dc.contributor.author | Probert, Christopher S. | |
dc.date.accessioned | 2022-06-15T12:46:36Z | |
dc.date.available | 2022-06-15T12:46:36Z | |
dc.date.issued | 2015 | |
dc.identifier.citation | Obayo, S., Muzoora, C., Ocama, P., Cooney, M. M., Wilson, T., & Probert, C. S. (2015). Upper gastrointestinal diseases in patients for endoscopy in South-Western Uganda. African Health Sciences, 15(3), 959-966. | en_US |
dc.identifier.uri | http://ir.must.ac.ug/xmlui/handle/123456789/2143 | |
dc.description.abstract | Background: There is a paucity of published data regarding upper gastrointestinal diseases in Ugandans with upper gastrointestinal symptoms referred for endoscopy.
Objectives: To study the presenting complaints, pathology and Helicobacter pylori prevalence among patients with upper gastrointestinal symptoms in South-Western Uganda.
Methods: Patients presenting with upper gastrointestinal symptoms underwent upper endoscopy and a urease test for Helicobacter Pylori, all suspicious lesions were biopsied for histopathology review as appropriate.
Results: The most common presenting complaints were epigastric pain (51.6%), dysphagia (13.6%) and odynophagia (7.1%). The most common endoscopy finding was gastritis (40.2%), followed by normal examination (15.2%), oesophageal cancer (13.6%), gastric ulcer (7.6%) and gastric cancer (7.1%). Patients older than 40 years (n=110) had significant findings including gastritis (50.9%), oesophageal cancer (22.7%) and gastric cancer (11.8%). However, in younger patients, with the age range of 18-40 years (n=74), most examinations were normal (92.9%). Of the 176 patients able to undergo Helicobacter pylori testing 75.6% were positive. Helicobacter pylori infection was associated with statistically significant increase in gastritis, oesophageal cancer, gastric ulcer, gastric cancer, and duodenal ulcers (p-values< 0.05).
Conclusion: Gastritis, ulcerative disease, and upper gastrointestinal malignancies are common in South-Western Ugandans and are associated with a high prevalence of Helicobacter pylori | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | African Health Sciences | en_US |
dc.subject | Upper gastrointestinal symptoms | en_US |
dc.subject | Pathology | en_US |
dc.subject | Urease test | en_US |
dc.subject | Helicobacter pylori | en_US |
dc.subject | Endoscopy | en_US |
dc.subject | Uganda | en_US |
dc.title | Upper gastrointestinal diseases in patients for endoscopy in South-Western Uganda | en_US |
dc.type | Article | en_US |