Research Articles: Recent submissions
Now showing items 101-120 of 456
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Updating vital status by tracking in the community among patients with epidemic Kaposi sarcoma who are lost to follow-up in sub-Saharan Africa
(BMC cancer, 2017)Background: Throughout most of sub-Saharan Africa (and, indeed, most resource-limited areas), lack of death registries prohibits linkage of cancer diagnoses and precludes the most expeditious approach to determining cancer ... -
Factors associated with retention of health workers in remote public health centers in Northern Uganda: a cross‑sectional study
(Human Resources for Health, 2023)Background: Health worker retention in remote and hard-to-reach areas remains a threat in most low- and middle income countries, and this negatively impacts health service delivery. The health workforce inequity is ... -
Empiric Deworming and CD4 Count Recovery in HIVInfected Ugandans Initiating Antiretroviral Therapy
(PLoS neglected tropical diseases, 2014)Background: There is conflicting evidence on the immunologic benefit of treating helminth co-infections (‘‘deworming’’) in HIV-infected individuals. Several studies have documented reduced viral load and increased CD4 count ... -
Program Implementation of Option B– at a President’s Emergency Plan for AIDS Relief-Supported HIV Clinic Improves Clinical Indicators But Not Retention in Care in Mbarara, Uganda
(AIDS patient care and STDs, 2017)2013 WHO guidelines for prevention of mother to child transmission recommend combination antiretroviral therapy (ART) for all pregnant women, regardless of CD4 count (Option B/B+). We conducted a retrospective analysis of ... -
Effect of two counseling interventions on self-reported alcohol consumption, alcohol biomarker phosphatidylethanol (PEth), and viral suppression among persons living with HIV (PWH) with unhealthy alcohol use in Uganda: A randomized controlled trial
(Drug and alcohol dependence, 2023)Purpose: To test the efficacy of two interventions to reduce alcohol use and increase viral suppression compared to a control in persons with HIV (PWH). Methods: In a three-arm (1:1:1) randomized controlled trial (N = ... -
Retinopathy among women with hypertensive disorders of pregnancy attending hospitals in Mbarara city, south-western Uganda: a cross-sectional study
(BMJ open, 2023)Objective: Retinopathy is one of the complications occurring among women with hypertensive disorders of pregnancy. We sought to determine the prevalence and factors associated with retinopathy among women with hypertensive ... -
The recent outbreak of dengue in Bangladesh is a public and global threat to the international communities; what should we do to mitigate it?
(International Journal of Surgery: Global Health, 2023)Dengue fever, formerly known as tropical influenza or red fever, is a viral infection transmitted to humans by the bite of infected mosquitoes of the species Aedes Aegypti. (1) This mosquito-borne illness is widely spread ... -
Assessing the Quality and Effectiveness of Alcohol Based Hand Sanitizers Commercially Available in Mbarara City
(Natural Products Chemistry & Research, 2023)Alcohol based hand sanitizers are currently recommended for routine use in curbing the spread of the serious infectious diseases like COVID-19. This survey examined hand sanitizers marketed in Mbarara city with regards to ... -
Acceptance of the coronavirus disease- 2019 vaccine among medical students in Uganda
(Tropical medicine and health, 2021)Background: COVID-19 is still a major global threat for which vaccination remains the ultimate solution. Uganda reported 40,751 cases and 335 deaths as of 9 April 2021 and started its vaccination program among priority ... -
Advancing detection and response capacities for emerging and re-emerging pathogens in Africa
(The Lancet Infectious Diseases, 2023)Recurrent disease outbreaks caused by a range of emerging and resurging pathogens over the past decade reveal major gaps in public health preparedness, detection, and response systems in Africa. Underlying causes of recurrent ... -
The benefits of care: treated HIV infection and health-related quality of life among older-aged people in Uganda
(Aging & Mental Health, 2023)Objectives: The objective of this study is to explore how HIV care affects health-related quality of life (HRQoL) among older people in Uganda. Methods: We enrolled older-aged (≥49 years) people with HIV receiving HIV ... -
Determinants of health-related quality of life in people with Human Immunodeficiency Virus, failing first-line treatment in Africa
(Health and Quality of Life Outcomes, 2023)Background: Antiretroviral treatment improves health related quality of life (HRQoL) of people with human immunodeficiency virus (PWH). However, one third initiating first-line treatment experience virological failure and ... -
Patient’s Perceptions of Anti-Cancer Chemotherapy Side Effects and Adherence on Treatment at Mbarara Regional Referral Hospital
(Student's Journal of Health Research Africa, 2023)Background: Chemotherapy is one of the most common treatment modalities for cancer. However, despite the benefits of indicated chemotherapy, the side effects and toxicities of the treatment frequently affect the patient’s ... -
Outcomes of WHO defined severe respiratory distress without shock in adults in sub- Saharan Africa
(American Journal of Respiratory and Critical Care Medicine, 2023)Sepsis is the leading cause of global mortality, and is most often attributed to lower respiratory tract infections and subsequent acute respiratory distress syndrome (ARDS) (1). The greatest burden of sepsis rests on ... -
Implementation of Hepatitis B Screening Into Routine Antenatal Care to Prevent Mother-to-Child Transmission in Rural Western Uganda
(In Open Forum Infectious Diseases, 2023)In rural Uganda where birth dose vaccination for hepatitis B is not routine, we implemented a pilot program for preventing mother-to-child transmission that effectively identified women with high-risk hepatitis B virus ... -
Health System Responsiveness for Persons with HIV and Disability in South Western Uganda
(HIV/AIDS-Research and Palliative Care, 2023)Background: Inequitable access to Human Immunodeficiency Virus/Acquired Immune Syndrome (HIV/AIDS) Treatment and Care Services (HATCS) for People with Disabilities (PWD) is a hurdle to ending the pandemic by 2030. The aim ... -
Development and Validation of the Soweto Coping Scale: A Mixed-Methods, Population-Based Study of Adults Living in Soweto, South Africa
(Journal of Affective Disorders, 2022)Mental health disorders are among the leading contributors to the burden of disease and need to be prioritised in policy making and program implementation. In the absence of mental healthcare, people often navigate their ... -
Linkage to HIV Care Following HIV Self‑testing Among Men: Systematic Review of Quantitative and Qualitative Studies from Six Countries in Sub‑Saharan Africa
(AIDS and Behavior, 2023)Gender disparities are pervasive throughout the HIV care continuum in sub-Saharan Africa, with men testing, receiving treatment, and achieving viral suppression at lower rates, and experiencing mortality at higher rates, ... -
Systematic Review of mHealth Interventions for Adolescent and Young Adult HIV Prevention and the Adolescent HIV Continuum of Care in Low to Middle Income Countries
(AIDS and Behavior, 2023)Adolescents and young adults (AYA) in low to middle income countries (LMIC) have poorer outcomes along each step in the HIV continuum of prevention and care compared to younger children or older adults. The use of mHealth ... -
Effect of the COVID-19 lockdown on the HIV care continuum in Southwestern Uganda: A time series analysis
(Plos one, 2023)Introduction: In Uganda, COVID-19 lockdown policies curbed the spread of SARS-CoV-2, but their effect on HIV care is poorly understood. Objectives: We examined the effects of COVID-19 lockdown policies on ART initiation, ...