Research Articles: Recent submissions
Now showing items 241-260 of 450
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Rethinking the ‘‘Pre’’ in Pre-Therapy Counseling: No Benefit of Additional Visits Prior to Therapy on Adherence or Viremia in Ugandans Initiating ARVs
(PLoS One, 2012)Background: Many guidelines recommend adherence counseling prior to initiating antiretrovirals (ARVs), however the additional benefit of pre-therapy counseling visits on early adherence is not known. We sought to assess ... -
Population pharmacokinetics of artemether and dihydroartemisinin in pregnant women with uncomplicated plasmodium falciparum malaria in uganda
(Malaria Journal, 2012-08-22)Background: Malaria in pregnancy increases the risk of maternal anemia, abortion and low birth weight. Approximately 85.3 million pregnancies occur annually in areas with Plasmodium falciparum transmission. Pregnancy ... -
Social Support, Food Insecurity, and HIV Stigma Among Men Living with HIV in Rural Southwestern Uganda: A Cross-Sectional Analysis
(HIV/AIDS - Research and Palliative Care, 2021)Background: HIV stigma is one of the major barriers to HIV care due to the fear of disclosure and social discrimination. HIV stigma among men in sub-Saharan countries, including Uganda, has been linked to the fear about ... -
Stakeholders’ Perceptions of Integrated Community Case Management by Community Health Workers: A Post- Intervention Qualitative Study
(PLoS One, 2014)Background: Integrated community case management (iCCM) involves delivery of simple medicines to children with pneumonia, diarrhea and/or malaria by community health workers (CHWs). Between 2010 and 2012, an iCCM intervention ... -
Multiple Measures Reveal Antiretroviral Adherence Successes and Challenges in HIV-Infected Ugandan Children
(PLoS ONE, 2012-05-09)Background: Adherence to HIV antiretroviral therapy (ART) among children in developing settings is poorly understood. Methodology/Principal Findings: To understand the level, distribution, and correlates of ART adherence ... -
Personal carbon monoxide exposure, respiratory symptoms, and the potentially modifying roles of sex and HIV infection in rural Uganda
(Environmental Health, 2019-08-20)Background: Most of the global burden of pollution-related morbidity and mortality is believed to occur in resource-limited settings, where HIV serostatus and sex may influence the relationship between air pollution exposure ... -
Persistent immune activation and carotid atherosclerosis in HIV-infected Ugandans receiving antiretroviral therapy
(The Journal of Infectious Diseases, 2022)Background. Human immunodefificiency virus (HIV) infection and associated immune activation predict the risk of cardiovascular disease in resource-rich areas. Less is known about these relationships in sub-Saharan Africa. ... -
Supportive supervision and constructive relationships with healthcare workers support CHW performance: Use of a qualitative framework to evaluate CHW programming in Uganda
(Human resources for health, 2018)Background: While evidence supports community health worker (CHW) capacity to improve maternal and newborn health in less-resourced countries, key implementation gaps remain. Tools for assessing CHW performance and evidence ... -
Monosodium Glutamate Maintains Antioxidant Balance in the Neuro-Retinal Axis of Male Wistar Rats
(Research square, 2021-05-17)Purpose: Information on monosodium glutamate (MSG) safety in the eye-brain axis remains scarce. The objective of the study was to establish changes in calcium (Ca2+) concentrations, catalase activity, Malondialdehyde (MDA) ... -
Effect of age at initiation of antiretroviral therapy on treatment outcomes; A retrospective cohort study at a large HIV clinic in southwestern Uganda
(PLOS ONE, 2018-08)Background: The prevalence of HIV infection among older persons is increasing yet older age at initiation of antiretroviral therapy (ART) may be associated with poorer treatment outcomes including mortality. However, ... -
Drugs for some but not all: inequity within community health worker teams during introduction of integrated community case management
(BMC health services research, 2014)Background: The Ugandan health system now supports integrated community case management (iCCM) by community health workers (CHWs) to treat young children ill with fever, presumed pneumonia, and diarrhea. During an iCCM ... -
Lung function and atherosclerosis: a cross‑sectional study of multimorbidity in rural Uganda
(BMC Pulmonary Medicine, 2022)Background: Chronic obstructive pulmonary disease (COPD) is a leading cause of global mortality. In high-income settings, the presence of cardiovascular disease among people with COPD increases mortality and complicates ... -
Longitudinal assessment of associations between food insecurity, antiretroviral adherence and HIV treatment outcomes in rural Uganda
(AIDS, 2015-11-02)Introduction: Food insecurity is a potentially important barrier to the success of antiretroviral treatment (ART) programs in resource-limited settings. We undertook a longitudinal study in rural Uganda to estimate the ... -
Lessons Learned From and Future Opportunities for Global Health Endeavors by 2 Academic Gastroenterology Units
(Gastroenterology, 2019-11-01) -
Diminishing Availability of Publicly Funded Slots for Antiretroviral Initiation among HIV-Infected ART-Eligible Patients in Uganda
(PLoS ONE, 2010-11)Background: The impact of flat-line funding in the global scale up of antiretroviral therapy (ART) for HIV-infected patients in Africa has not yet been well described. Methods: We evaluated ART-eligible patients and ... -
Knowledge of obstetric danger signs and birth preparedness practices among women in rural Uganda
(Reproductive Health, 2011-11-06)Background: Improving knowledge of obstetric danger signs and promoting birth preparedness practices are strategies aimed at enhancing utilization of skilled care in low-income countries. The aim of the study was to explore ... -
Introduction of mobile phones for use by volunteer community health workers in support of integrated community case management in Bushenyi District, Uganda: development and implementation process
(BMC Health Services Research, 2014-05-12)Background: A substantial literature suggests that mobile phones have great potential to improve management and survival of acutely ill children in rural Africa. The national strategy of the Ugandan Ministry of Health calls ... -
Real-time Adherence Monitoring of Antiretroviral Therapy Among HIV-infected Adults and Children in Rural Uganda
(AIDS, 2013)A real-time wireless electronic adherence monitor(EAM) and weekly self-report of missed doses via interactive voice response (IVR) and short message service (SMS) queries were used to measure ART adherence in 49 adults and ... -
Intimate partner violence, spouse extramarital affairs, and depression among women in rural Uganda
(Research square, 2021-04-12)Background: Depression is highly prevalent among women compared to men. Women in rural areas are more at risk of depression compared to their peers in urban areas. Some of the factors associated with depression among married ... -
Diagnostic accuracy of Xpert MTB/RIF Ultra for tuberculous meningitis in HIV-infected adults: a prospective cohort study
(The Lancet Infectious Diseases, 2017-09-14)Background: WHO recommends Xpert MTB/RIF as initial diagnostic testing for tuberculous meningitis. However, diagnosis remains difficult, with Xpert sensitivity of about 50–70% and culture sensitivity of about 60%. We ...