Research Articles: Recent submissions
Now showing items 41-60 of 445
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Social network correlates of free and purchased insecticide-treated bed nets in rural Uganda
(Malaria journal, 2022)Background: Malaria is a major cause of mortality and morbidity in Uganda. Despite Uganda’s efforts to distribute bed nets, only half of households have achieved the World Health Organization (WHO) Universal Coverage ... -
Are rapid diagnostic tests more accurate in diagnosis of malaria compared to microscopy?
(Malaria Journal, 2010)Prompt, accurate diagnosis and treatment with artemisinin combination therapy remains vital to current malaria control. Blood film microscopy the current standard test for diagnosis of malaria has several limitations that ... -
Are rapid diagnostic tests more accurate in diagnosis of plasmodium falciparum malaria compared to microscopy at rural health centres?
(Malaria journal, 2010)Background: Prompt, accurate diagnosis and treatment with artemisinin combination therapy remains vital to current malaria control. Blood film microscopy the current standard test for diagnosis of malaria has several ... -
Trust in Medical Research: A comparative study among Patients at a Regional Referral Hospital and Community Members in Lira District, Northern Uganda
(Journal of Empirical Research on Human Research Ethics, 2024)Events such as the Tuskegee syphilis study shaped how the public perceives and trusts medical research globally. However, few studies have examined trust in medical research in developing countries. We tested the hypothesis ... -
Adaptation of the Client Diagnostic Questionnaire for East Africa
(PLOS Global Public Health, 2024)Research increasingly involves cross-cultural work with non-English-speaking populations, necessitating translation and cultural validation of research tools. This paper describes the process of translating and criterion ... -
The Drinkers’ Intervention to Prevent Tuberculosis (DIPT) trial among heavy drinkers living with HIV in Uganda: study protocol of a 2×2 factorial trial
(Trials, 2021)Background: The risk of tuberculosis (TB) is high among people with HIV (PWH). Heavy alcohol drinking independently increases TB risk and approximately 25% of PWH globally engage in heavy drinking. While isoniazid (INH) ... -
Integration of HIV Testing in a Community Intervention for Tuberculosis Screening Among Household Contacts of Patients with Tuberculosis in Cameroon and Uganda
(JAIDS Journal of Acquired Immune Deficiency Syndromes, 2024)Introduction: People living with HIV are considered at higher risk of developing severe forms of tuberculosis (TB) disease. Providing HIV testing to TB-exposed people is therefore critical. We present the results of ... -
Negative effects of undernutrition on sputum smear conversion and treatment success among retreatment cases in Uganda: A quasi-experimental study
(Journal of Clinical Tuberculosis and Other Mycobacterial Diseases, 2024)Rationale: The causal relationship between undernutrition and response to anti-tuberculosis (TB) treatment and TB treatment outcomes among people with retreatment TB is understudied. Objective: To evaluate the effect of ... -
Effect of disclosure of HIV status on patient representation and adherence to clinic visits in eastern Uganda: A propensity-score matched analysis
(Plos one, 2021)Background: Disclosure of human immunodeficiency virus (HIV) status improves adherence to antiretroviral therapy (ART) and increases the chance of virological suppression and retention in care. However, information on the ... -
Voluntariness of consent in paediatric HIV clinical trials: a mixed- methods, cross- sectional study of participants in the CHAPAS- 4 and ODYSSEY trials in Uganda
(BMJ Open, 2024)Objectives: To examine the voluntariness of consent in paediatric HIV clinical trials and the associated factors. Design: Mixed- methods, cross- sectional study combining a quantitative survey conducted concurrently with ... -
Opportunities to Harness Technology to Deliver HIV Prevention / Healthy Sexuality Programming to Sexual and Gender Minority Adults Living in East Africa
(AIDS and Behavior, 2021)Because of stigmatization of and discrimination against lesbian, gay, bisexual, transgender, and other sexual and gender minority (SGM) people in East Africa, there is paucity of SGM-focused sexual health research. ... -
Immunologic Pathways That Predict Mortality in HIV-Infected Ugandans Initiating Antiretroviral Therapy
(The Journal of infectious diseases, 2017)The plasma kynurenine/tryptophan (KT) ratio, a marker of adaptive immune defects, strongly predicts mortality during treated human immunodeficiency virus (HIV) disease in Ugandans as compared to US-based populations. Here, ... -
ART adherence and viral suppression are high among most non-pregnant individuals with early-stage, asymptomatic HIV infection: an observational study from Uganda and South Africa
(Journal of the International AIDS Society, 2019)Introduction: The success of universal antiretroviral therapy (ART) access and aspirations for an AIDS-free generation depend on high adherence in individuals initiating ART during early-stage HIV infection; however, ... -
Rethinking the ‘‘Pre’’ in Pre-Therapy Counseling: No Benefit of Additional Visits Prior to Therapy on Adherence or Viremia in Ugandans Initiating ARVs
(PLoS One, 2012)Background: Many guidelines recommend adherence counseling prior to initiating antiretrovirals (ARVs), however the additional benefit of pre-therapy counseling visits on early adherence is not known. We sought to assess ... -
Association between obesity and combination antiretroviral therapy (cART) adherence among persons with early-stage HIV infection initiating cART
(International Journal of Obesity, 2021)Background: Obesity is common among people living with HIV (PLWH) and early-stage infection, yet associations with combination antiretroviral (cART) adherence are unclear. Methods: Among PLWH initiating cART in Uganda ... -
Implementing a Global Health Qualitative Research Study: Experiences of a Project Coordinator in Uganda
(The East African Health Research Journal, 2017)Qualitative research in global health requires substantial operational and logistical support during both the implementation phase and day-to-day operations. However, little to no published work shares the experiences of ... -
Influence of intensified adherence counselling on viral load suppression of people receiving antiretroviral therapy at a health centre IV in southwestern Uganda: a qualitative study
(AIDS Research and Therapy, 2021)Background: The prevalence of Human Immunodeficiency Virus (HIV) among adults and children in Uganda is 6.2% and 0.5% respectively. The prevalence of viral load suppression in Uganda among all adults and children living ... -
HIV, Social Networks, and Loneliness among Older Adults in Uganda
(AIDS and Behavior, 2024)Loneliness among older adults has been identified as a major public health problem. Yet little is known about loneliness, or the potential role of social networks in explaining loneliness, among older people with HIV (PWH) ... -
Process evaluation of a parent-child communication intervention for adolescent sexual and reproductive health in Uganda
(BMC Public Health, 2024)Background: Previous initiatives concerning adolescent sexual and reproductive health (SRH) education in Lowor-Middle Income Countries (LMICs) have been limited by cultural norms and misinformation perpetuated within ... -
Determinants of a high prevalence of cesarean section among women in eastern Uganda
(The Pan African Medical Journal, 2023)Introduction: increasing proportion of Uganda women deliver by cesarean section (C-section) but limited studies have examined the determinants of C-section. We investigated the prevalence and determinants of C-section among ...