dc.description.abstract | The study aimed at establishing the etiology of urogenital discharges and their antibiograms in HIV/AIDS positive patients attending the HIV/AIDS clinic at Bwizibwera health center IV in Mbarara district, Uganda. This was a non- interventional descriptive laboratory based study. Forty (40) HIV positive patients with a urogenital discharge, read, understood and signed the consent forms were enrolled into the study. Of these, (47.5%, 19/40) were males and (52.5%, 21/40) were females. Out of eighty (80) urogenital swabs obtained, 40 of them were cultured on various culture media while the other 40 were used for serological tests. Chloramphenicol, penicillin, ceftriaxone, gentamycin, erythromycin and tetracycline antibiotics were used for sensitivity.A total of nine microorganisms were isolated [N. Gonorrhoeae (37.1%, 13/35), Staphylococcus aureus (22.9%, 8/35), Candida albicans (14.3%, 5/35),Enterococcus faecalis (8.6%, 3/35), Klebsiella pneumonia (5.7%, 2/35), non C. albicans species (2.9%, 1/35), Escherichia coli (2.9%, 1/35), Pseudomonas stuttzeri (2.9%, 1/35) and Pseudomonas aeruginosa (2.9%, 1/35)], serologically, all participants tested negative for Chlamydia.Majority of the isolates were sensitive to chloramphenicol (85.2%, 23/27), gentamycin (66.7%, 18/27), erythromycin (68.2%, 15/22) and lastly ceftriaxone (51.9%, 14/27), but also resistant to penicillin (59.1%, 13/22) and tetracycline (51.9%, 14/27).The study revealed Gonorrhoea (37.1%) as the highly prevalent urogenital infection and the least was candidiasis. Most of the isolates proved sensitive to chloramphenicol, gentamycin, erythromycin and ceftriaxone, as applied antibiotics in this study and resistant to only two of them i.e. penicillin and tetracycline. | en_US |