Browsing Research Articles by Issue Date
Now showing items 1-20 of 111
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Acceptance of HIV testing among women attending antenatal care in south-western Uganda: risk factors and reasons for test refusal
(AIDS care, 2008)A problem commonly encountered in programs for prevention of mother-to-childtransmission (PMTCT) of HIV in sub-Saharan Africa is low rates of HIV test acceptance among pregnant women. In this study, we examined risk factors ... -
Red blood cell alloimmunization from an African perspective
(Current Opinion in Hematology, 2010)Purpose of review: Red blood cell (RBC) alloimmunization occurs when individuals are exposed to erythrocytes that express blood group antigens different from their own. Consequences of alloimmunization include hemolytic ... -
Prevalence and specificities of red blood cell alloantibodies in transfused Ugandans with different diseases
(Vox sanguinis, 2010)Background and Objectives Alloantibody formation against red blood cell (RBC) antigens is a common complication of transfusion therapy. However, the prevalence of RBC alloimmunization is hardly known in Black Africans. In ... -
Assessment of the clinical transfusion practice at a regional referral hospital in Uganda
(Transfusion medicine, 2010)The aim of this study was to determine the indications for transfusion, blood ordering practices and post-transfusion complications, and to assess the clinical transfusion practice at Mbarara Regional Referral Hospital ... -
Red blood cell alloimmunization in sickle cell disease patients in Uganda
(Transfusion, 2010)BACKGROUND: Blood transfusion is an integral part in the management of sickle cell disease (SCD) patients. Alloimmunization is a recognized complication of red blood cell (RBC) transfusions with consequences including ... -
Red blood cell alloimmunization and antigen matching in sickle cell disease – the African perspective
(ISBT Science Series, 2012)In sickle cell disease (SCD), blood transfusion facilitates improved blood and tissue oxygenation, reduces the propensity to sickling by diluting host cells, and suppresses the production of red blood cells (RBCs) containing ... -
Prospective evaluation of the impact of potent antiretroviral therapy on the incidence of Kaposi’s Sarcoma in East Africa: findings from the International Epidemiologic Databases to Evaluate AIDS (IeDEA) Consortium
(Infectious Agents and Cancer, 2012)Prior to the rollout of potent antiretroviral therapy (ART), Kaposi’s sarcoma (KS) was the most commonly reported malignancy in many resource-limited settings, such as most of sub-Saharan Africa. In resource-replete settings ... -
Etiology of urogenital discharges and their antibiograms in HIV/AIDS positive patients at Bwizibwera Health Centre IV: Mbarara District- Uganda
(Journal Issues, 2014)The study aimed at establishing the etiology of urogenital discharges and their antibiograms in HIV/AIDS positive patients attending the HIV/AIDS clinic at Bwizibwera health center IV in Mbarara district, Uganda. This was ... -
Regulation of medical diagnostics and medical devices in the East African community partner states
(BMC health services research, 2014)Background: Medical devices and in vitro diagnostic tests (IVD) are vital components of health delivery systems but access to these important tools is often limited in Africa. The regulation of health commodities by National ... -
Multisite Validation of Cryptococcal Antigen Lateral Flow Assay and Quantification by Laser Thermal Contrast
(Emerging infectious diseases, 2014-01)Cryptococcal meningitis is common in sub-Saharan Africa. Given the need for data for a rapid, point-of-care cryptococcal antigen (CRAG) lateral flow immunochromatographic assay (LFA), we assessed diagnostic performance of ... -
Incidence and Predictors of Pregnancy among a Cohort of HIV-Positive Women Initiating Antiretroviral Therapy in Mbarara, Uganda
(PLOS ONE, 2014-05-22)Objective: Many people living with HIV in sub-Saharan Africa desire biological children. Implementation of HIV prevention strategies that support the reproductive goals of people living with HIV while minimizing HIV ... -
The Etiology and Antibiogram of Bacterial Causes of Conjunctivitis among Patients Attending the Eye Clinic at Rugarama Hospital in South Western Uganda
(Ophthalmology Research: An International Journal, 2014-07-17)Background: Bacterial Conjunctivitis is a common eye condition that causes discomfort and is very irritating. It is a common condition in children and adults and can be caused by various bacterial agents. Objective: To ... -
Epidemiology of Carbapenem Resistance among Multi-drug Resistant Enterobacteriaceae in Uganda
(British Microbiology Research Journal, 2015)Background: Multi-drug resistant (MDR) Enterobacteriaceae are on the increase worldwide and their spread has become a global challenge. Escalating the challenge is the possibility that many of these are Carbapenemase-producing ... -
Occurrence of anti-D alloantibodies among pregnant women in Kasese District, Western Uganda
(Journal of blood medicine, 2015)Objectives: This study was undertaken to determine the distribution of ABO/RhD (rhesus D antigen) blood phenotypes, prevalence of anti-D alloantibodies, and the risk factors for alloim-munization among pregnant women in ... -
Transfusion Medicine in Sub-Saharan Africa: Conference Summary
(Transfusion medicine reviews, 2015)In November 2014, a 3-day conference devoted to transfusion medicine in sub-Saharan Africa was held in Kampala, Uganda. Faculty from academic institutions in Uganda provided a broad overview of issues pertinent to transfusion ... -
Prevalence of HI V-related thrombocytopenia among clients at Mbarara Regional Referral Hospital, Mbarara, southwestern Uganda
(Journal of Blood Medicine, 2015-04-10)Aims/objectives: We aimed to determine the prevalence and correlates of thrombocytopenia among people living with human immunodeficiency virus (HIV)/acquired immune deficiency syndrome (AIDS) and to assess occurrence of ... -
Bacterial and Drug Susceptibility Profiles of Urinary Tract Infection in Diabetes Mellitus Patients at Mbarara Regional Referral Hospital, Uganda
(British Microbiology Research Journal, 2015-07-06)Aim: The risk of developing infection in diabetic mellitus patients is known to be higher than in normal individuals. The urinary tract is the most common entry point of infections. Surveillance of urinary tract pathogens ... -
A review of antimicrobial resistance in East Africa
(African Journal of Laboratory Medicine, 2016)Background and objectives: Knowledge of local and regional antimicrobial resistance (AMR) is important for clinical decision making. However, surveillance capacity for AMR is lacking throughout East Africa, and current AMR ... -
Red blood cell alloimmunization in transfused patients in sub-Saharan Africa: A systematic review and meta-analysis
(Transfusion and Apheresis Science, 2016)Background and objectives: Previous studies of Sub-Saharan Africans show significant alloimmunization to red blood cell (RBC) antigens, but country-specific data are limited. Thus, the aim of this study was to estimate, ... -
A systematic review of red blood cell alloimmunization in pregnant women in Africa: time to do better
(ISBT Science Series, 2016)Background and objectives: The presence of red blood cell (RBC) alloantibodies in pregnant women has been linked to the significant perinatal morbidity and mortality. A limited number of African studies have assessed ...
