Department of Peadiatrics and Child Health: Recent submissions
Now showing items 41-60 of 118
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Money was the Problem”: Financial Difficulty is the Main Reason for Treatment Abandonment by Children with Cancer in South West Uganda
(2021)Introduction: Treatment abandonment contributes significantly to poor survival of children with cancer in low-middle-income countries (LMICs). In order to inform an approach to this problem at our Cancer Unit, we investigated ... -
Modeling a BCG Birth Dose-based Vaccination Program for Improved Hepatitis B Control in Uganda: Mixed-methods study
(Research square, 2022)Background: Hepatitis B virus (HBV) is mainly transmitted perinatally. Delaying the first dose of HBV vaccine to 6 weeks of age as is the current practice in Uganda may increase the risk of perinatal transmission. In this ... -
Innovations in Cardiorespiratory Monitoring to Improve Resuscitation With Helping Babies Breathe
(Pediatrics, 2020)Ninety percent of intrapartum-related neonatal deaths are attributable to respiratory depression, with the vast majority of these deaths occurring in low- and lower middle– income countries. Neonatal resuscitation training ... -
Individual, maternal and household risk factors for anaemia among young children in sub-Saharan Africa: a crosssectional study
(BMJ open, 2018)Objective: Anaemia affects the majority of children in sub- Saharan Africa (SSA). Previous studies of risk factors for anaemia have been limited by sample size, geography and the association of many risk factors with ... -
Health hackathons: theatre or substance? A survey assessment of outcomes from healthcare-focused hackathons in three countries
(BMJ innovations, 2017-01-04)Background: Healthcare-focused hackathons are 48-hour platforms intended to accelerate novel medical technology. However, debate exists about how much they contribute to medical technology innovation. The Consortium for ... -
Development and Impact of Helping Babies Breathe Educational Methodology
(Pediatrics, 2020)The educational pedagogy surrounding Helping Babies Breathe (HBB) has been transformative in going beyond a curriculum focused only on basic neonatal resuscitation; indeed, it created the framework for an educational program ... -
A qualitative study of the perspectives of health workers and policy makers on external support provided to low-level private health facilities in a Ugandan rural district, in management of childhood infections
(Global Health Action, 2021)Background: With the under-five child mortality rate of 46.4 deaths per 1000 live births, Uganda should accelerate measures to reduce child deaths to achieve the Sustainable Development Goal 3. While 60–70% of frontline ... -
The development and implementation of a theory-informed, integrated mother-child intervention in rural Uganda
(Social Science & Medicine, 2015)Rationale: A randomised cluster effectiveness trial of a parenting intervention in rural Uganda found benefits to child development among children 12e36 months, relevant parenting practices related to stimulation, hygiene ... -
Sexual Relationship Power and Depression among HIVInfected Women in Rural Uganda
(PLoS ONE, 2012)Background: Depression is associated with increased HIV transmission risk, increased morbidity, and higher risk of HIV related death among HIV-infected women. Low sexual relationship power also contributes to HIV risk, but ... -
Prospective study of the mental health consequences of sexual violence among women living with HIV in rural Uganda
(Journal of interpersonal violence, 2016)The association between sexual violence and depression is well known, but the temporal aspects of the association have not been well established. We analyzed data from a cohort of 173 HIV-positive women in rural Uganda who ... -
Point-of-Care Approaches for Meningitis Diagnosis in a Low-Resource Setting (Southwestern Uganda): Observational Cohort Study Protocol of the “PI-POC” Trial
(JMIR Research Protocols, 2020)Background: A timely differential diagnostic is essential to identify the etiology of central nervous system (CNS) infections in children, in order to facilitate targeted treatment, manage patients, and improve clinical ... -
Pediatric Post-Discharge Mortality in Resource Poor Countries: A Systematic Review
(PLoS ONE, 2013-06-25)Objectives: Mortality following hospital discharge is an important and under-recognized contributor to overall child mortality in developing countries. The primary objective of this systematic review was to identify all ... -
Outcome of Children with Presumptive Tuberculosis in Mbarara, Rural Uganda
(The Pediatric Infectious Disease Journal, 2018)Background: Mortality among children with presumptive tuberculosis (TB) empiric TB treatment can be high. We describe the predictors of death among children with presumptive TB, and the relation between treatment and ... -
Effects of a parenting intervention to address maternal psychological wellbeing and child development and growth in rural Uganda: a community-based, cluster-randomised trial
(The Lancet Global Health, 2015-07-03)Background: Parenting interventions have been implemented to improve the compromised developmental potential among 39% of children younger than 5 years living in low-income and middle-income countries. Maternal wellbeing ... -
Detection Yield and Tolerability of String Test for Diagnosis of Childhood Intrathoracic Tuberculosis
(The Pediatric infectious disease journal, 2016)Background: Difficulty to obtain sputum in children complicates diagnosis of intrathoracic tuberculosis (TB). The intragastric string test (ST) used for retrieval of enteric pathogens might be an alternative specimen ... -
Treatment outcomes and tolerability of the revised WHO anti-tuberculosis drug dosages for children
(The International Journal of Tuberculosis and Lung Disease, 2018)Background: In 2010, the World Health Organization (WHO) revised the paediatric dosages of antituberculosis drugs, increasing rifampicin to 15 mg/kg, isoniazid to 10 mg/kg and pyrazinamide to 35 mg/kg. We assessed treatment ... -
A qualitative study of the acceptability of remote electronic bednet use monitoring in Uganda
(BMC Public Health, 2022)Background: Distribution of long-lasting insecticide treated nets (LLINs) is the most widely used intervention for the prevention of malaria but recall and social desirability biases may lead to challenges in accurately ... -
Tuberculosis in children at Mbarara University Teaching Hospital, Uganda: diagnosis and outcome of treatment
(African Health Sciences, 2002)Background: The diagnosis of tuberculosis in children is difficult particularly in HIV infected children. The poor outcome following antituberculosis treatment usually reported in HIV infected children might be due, in ... -
The Technology Acceptance Model for Resource-Limited Settings (TAM-RLS): A Novel Framework for Mobile Health Interventions Targeted to Low-Literacy End-Users in Resource-Limited Settings
(AIDS and Behavior, 2017)Although mobile health (mHealth) technologies have shown promise in improving clinical care in resource limited settings (RLS), they are infrequently brought to scale. One limitation to the success of many mHealth interventions ... -
The Bacterial and Viral Complexity of Post-infectious Hydrocephalus in Uganda
(Science translational medicine, 2020-05-06)Postinfectious hydrocephalus (PIH), often following neonatal sepsis, is the most common cause of pediatric hydrocephalus world-wide, yet the microbial pathogens remain uncharacterized. Characterization of the microbial ...
