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dc.contributor.authorMusinguzi, Nicholas
dc.contributor.authorStanford, Fatima Cody
dc.contributor.authorBoatin, Adeline A.
dc.contributor.authorOrrell, Catherine
dc.contributor.authorAsiimwe, Stephen
dc.contributor.authorSiedner, Mark
dc.contributor.authorHaberer, Jessica E.
dc.contributor.authoron behalf of the META team
dc.date.accessioned2024-02-26T13:41:03Z
dc.date.available2024-02-26T13:41:03Z
dc.date.issued2021
dc.identifier.citationMusinguzi, N., Stanford, F. C., Boatin, A. A., Orrell, C., Asiimwe, S., Siedner, M., & Haberer, J. E. (2021). Association between obesity and combination antiretroviral therapy (cART) adherence among persons with early-stage HIV infection initiating cART. International Journal of Obesity, 45(8), 1855-1859.en_US
dc.identifier.urihttp://ir.must.ac.ug/xmlui/handle/123456789/3426
dc.description.abstractBackground: Obesity is common among people living with HIV (PLWH) and early-stage infection, yet associations with combination antiretroviral (cART) adherence are unclear. Methods: Among PLWH initiating cART in Uganda and South Africa, body mass index (BMI) was assessed at cART initiation, and cART adherence was monitored in real-time over 12 months. The association of obesity (BMI≥30kg/m2) with adherence was assessed among non-pregnant participants with CD4>350 cells/mm3 using fractional regression modeling. Results: Among 322 participants, median age was 32 years, 70% were female, and 54% were from Uganda. Prevalence of obesity was 12% in Uganda and 28% in South Africa. Mean overall cART adherence was 83% in Uganda and 66% in South Africa. Participants with obesity had higher adherence than those without obesity: +3.6% (p=0.44) in Uganda and +11.4% (p=0.02) in South Africa. Conclusion: Obesity at cART initiation was common and associated with higher adherence, although only significantly in South Africa.en_US
dc.description.sponsorshipBill and Melinda Gates Foundation (OPP1056051)en_US
dc.language.isoen_USen_US
dc.publisherInternational Journal of Obesityen_US
dc.subjectObesityen_US
dc.subjectAntiretroviral therapyen_US
dc.subjectHIVen_US
dc.subjectPersonsen_US
dc.titleAssociation between obesity and combination antiretroviral therapy (cART) adherence among persons with early-stage HIV infection initiating cARTen_US
dc.typeArticleen_US


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