Reducing stroke burden through a targeted self-management intervention for reducing stroke risk factors in high-risk Ugandans: A protocol for a randomized controlled trial
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Date
2021Author
Kaddumukasa, Mark
Najjuma, Josephine
Mbalinda, Scovia Nalugo
Kaddumukasa, Martin N.
Nakibuuka, Jane
Burant, Christopher
Moore, Shirley
Blixen, Carol
Katabira, Elly T.
Sajatovic, Martha
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Introduction: Stroke burden is rapidly increasing globally. Modifiable risk factors offer an opportunity to intervene, and targeting hypertension is a key actionable target for stroke risk reduction in sub-Saharan Africa. This 3-site planned randomized controlled trial builds on promising preliminary data.
Methods: A total of 246 Ugandan adults will be recruited randomized to experimental intervention vs. enhanced treatment control. Intervention participants will receive six weekly group-format stroke risk reduction self-management training sessions, and the controls will receive information on cardiovascular risk. The primary study outcome is systolic B.P. measured at baseline, 13-week, 24 weeks (6 months). Secondary outcomes include other biological and behavioral stroke risk factors.
Discussion: The curriculum-guided self-management Targeted Management Intervention (TEAM) program is anticipated to reduce the stroke burden in Uganda.
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