African Journal of Pharmacy and Pharmacology Phytochemical and efficacy study on four herbs used in erectile dysfunction: Mondia whiteii, Cola acuminata, Urtica massaica, and Tarenna graveolens
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Date
2016-10-10Author
Oloro, Joseph
Julius Kihdze Tanayen, Julius
Barbra Katusiime, Barbrarbra
Lawrence Imanirampa, Imanirampa
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Show full item recordAbstract
here is a resurgence in the use of herbal medicine in the developed countries, with even much more in
low developed Countries and especially for conditions such as erectile dysfunction. Studies thus need
to be conducted to scientifically validate claims on certain medicinal plants reported to be efficacious in
traditional medicine. This current study was conducted to determine the phytochemical composition
and efficacy of four herbs Mondia whiteii (Hook. F.) roots locally called (Mulondo), Cola acuminata (P.
Beauv.) fruits locally called (Engongoli), Urtica massaica (Mildbr) leaves, locally called (Engyenyi) and
Tarenna graveolens (S. Moore) roots, locally called (Munywamaizi) in Runyankole which have been
reported as remedies for the management of erectile dysfunction in South-western Uganda.
Phytochemical screening was conducted following methods described in Kokate, Trease and Evans.
Sexual function was tested using both the contact and non-contact model. Arginine was present in all
the extracts. Aqueous extract of Tarenna graveolens significantly improved testosterone levels but
none of the extracts had significant effects on mounting frequency. Aqueous extract of Tarrena
graveolens could be useful in management of erectile dysfunction associated with hypogonadism.
Key words: Erectile dysfunction, efficacy, phytochemical, testosterone, Mondia, Cola, Urtica, Tarenna.