Research Articles: Recent submissions
Now showing items 1-20 of 111
-
Proteinuria as a Critical Indicator of Kidney Dysfunction in Type 2 Diabetes Patients: Insights From a Cross-Sectional Study
(Cureus, 2024)Background: Kidney dysfunction is a common finding among patients with diabetes mellitus. We sought to determine the prevalence and contributors to kidney dysfunction among type 2 diabetes mellitus (T2D) patients. Methods: ... -
Serum Uric Acid and Microalbuminuria: Predictors of Renal Dysfunction in Type 2 Diabetes Patients in South-Western Uganda
(Cureus, 2024)Background: Type 2 diabetes (T2D) is a chronic metabolic disorder characterized by insulin resistance and high blood glucose levels, which has become a global pandemic in recent decades and is associated with several health ... -
Distribution of the ACE Gene Polymorphisms in Type 2 Diabetes Mellitus Patients, Their Associations with Nephropathy Biomarkers and Metabolic Indicators at a Tertiary Hospital in Uganda
(Diabetes, Metabolic Syndrome and Obesity, 2024)Purpose: We aimed at determining the distribution of the ACE insertion/deletion gene polymorphisms among type 2 diabetic patients and their association with the nephropathy biomarkers and the metabolic indicators. Patients ... -
Association between fetal hemoglobin, lactate dehydrogenase, and disease severity in patients with sickle cell disease at Bugando Medical Centre, Mwanza, Tanzania
(Plos one, 2024)Introduction: There is a wide range of clinical manifestations in sickle cell disease (SCD). Despite having the same condition, each person’s response to disease complications differs greatly. Individuals can be categorized ... -
The diagnostic accuracy of serum and plasma microRNAs in detection of cervical intraepithelial neoplasia and cervical cancer: A systematic review and meta-analysis
(Gynecologic Oncology Reports, 2024)Studies suggest a need for new diagnostic approaches for cervical cancer including microRNA technology. In this review, we assessed the diagnostic accuracy of microRNAs in detecting cervical cancer and Cervical Intraepithelial ... -
Diagnostic Utility of GeneXpert MTB/RIF Assay in EPTB Detection in Formalin Fixed Paraffin Embedded Tissue Biopsies in South Western Uganda
(Pathology and Laboratory Medicine International, 2024)Purpose: Formalin-fixed tissue biopsies submitted to the Histopathology Laboratory were explored for possible use in the GeneXpert MTB/Rifampicin assay for EPTB diagnosis, therefore this study aimed to determine the ... -
Coping strategies, challenges and potential interventions among adult patients with HIV and mental illness comorbidity in southwestern Uganda
(Global Public Health, 2024)HIV and mental illness comorbidity presents significant healthcare challenges, especially in low- and middle-income countries where healthcare systems often address individual conditions rather than comorbidities. This ... -
Association between dyslipidemia and cervical intraepithelial neoplasia: A case-control study in south-western Uganda
(African Journal of Laboratory Medicine, 2024)Background: Altered lipid levels may be associated with the development of a number of malignancies, including cancer of the cervix. However, there is limited understanding of this relationship in the rural Ugandan context. ... -
Empowering Global AMR Research Community: Interactive GIS dashboards for AMR data analysis and informed decision making
(Wellcome Open Research, 2024)Background: Antimicrobial Resistance (AMR) is a critical global public health concern, demanding effective tools for research, data analysis, and decision-making. This study proposes a groundbreaking approach to empower ... -
Sero-antigen prevalence of lymphatic filariasis and risk factors of podoconiosis in Busiriba sub-county, Kamwenge district, Southwestern Uganda, August–September 2018
(BMC Research Notes, 2024)Objective: Given the neglected nature of filariasis, especially in Uganda where data are scarce, this cross-sectional study aimed to determine the sero-antigen prevalence of lymphatic filariasis and risk factors associated ... -
Evaluation of the Deki Reader™, an automated RDT reader and data management device, in a household survey setting in low malaria endemic southwestern Uganda
(Malaria journal, 2017)Background: Early diagnosis of suspected malaria cases with a rapid diagnostic test (RDT) has been shown to be an effective malaria control tool used in many resource‑constrained settings. However, poor quality control and ... -
Innovative laboratory methods for improved tuberculosis diagnosis and drug-susceptibility testing
(Frontiers in Tuberculosis, 2024)The laboratory plays a vital role in the diagnosis of all clinical forms of tuberculosis (TB), from microbiological confirmation of Mycobacterium tuberculosis to drug-susceptibility testing (DST) and treatment monitoring. ... -
Missed Diagnosis of Gestational Diabetes Mellitus Due to Selective Screening: Evidence from a Cross-Sectional Study in the West Nile Sub-Region, Uganda
(Diabetes, Metabolic Syndrome and Obesity, 2024)Purpose: To ascertain the prevalence and risk factors of gestational diabetes mellitus (GDM) in pregnant women receiving antenatal care (ANC) services within the West Nile subregion of Uganda. Patients and Methods: An ... -
Development of a customized m-Health-based intervention to reduce loss to follow-up among patients undergoing treatment for cervical lesions at a rural referral Hospital, South Western Uganda
(Gynecologic Oncology Reports, 2024)Background: Loss to follow-up (LTFU) in individuals undergoing cervical cancer treatment is a major challenge in many low resource settings. We describe development of a customized and tailored mHealth intervention for ... -
Insulin therapy among diabetic patients in rural communities of Sub-Saharan Africa: a perspective review
(Therapeutic Advances in Endocrinology and Metabolism, 2024)In this perspective review, we describe a brief background on the status quo of diabetes mellitus-related therapies and glycemic control among patients in rural communities in subSaharan Africa. The article discusses insulin ... -
Co-occurence of risky driving behaviours and associations with seatbelt and helmet use - a descriptive cross-sectional study among young adults
(Epidemiology Biostatistics and Public Health, 2019)Background: Greece exhibits one of the highest rates of deaths and injuries due to motor vehicle crashes in young adults in Europe. The personal, social and financial cost is still very high as road traffic crashes account ... -
Malaria infections among pregnant women attending antenatal clinic at Bududa hospital, eastern Uganda
(The Journal of Protozoology Research, 2019)Pregnancy-associated malaria is a major health concern in Bududa district. To assess the prevalence of malaria infection in pregnancy in Bududa District; a hospital-based, cross-sectional study was carried out. Two hundred ... -
Intestinal parasitic infections and associated factors among HIV/AIDS patients at Gulu regional referral hospital art clinic, Northern Uganda
(The Journal of Protozoology Research, 2021)Intestinal parasitic infections create a huge concern in the management and care of HIV positive people in Uganda. Understanding the prevalence and associated factors is vital for proper planning and patient management. ... -
Hepatitis B virus infection and HBeAg positivity among pregnant women in South West Uganda
(African Journal of Laboratory Medicine, 2022)Background: Hepatitis B virus is a public health burden in Uganda, yet little is known about its epidemiology in pregnancy. Objective: This study aimed at determining the prevalence and associated risk factors of hepatitis ... -
HRP2 and PLDH Performance Comparison as Rapid Diagnostic Tools for Symptomatic Malaria Patients at Rugazi HC IV in Rubirizi District
(International Internal Medicine Journal, 2024-02-13)Background: Rapid and precise laboratory diagnosis is essential for effectively diagnosing and managing malaria patients. Malaria rapid diagnostic tests (mRDTs) play a critical role in malaria diagnosis in resource-constrained ...
