Faculty of Medicine: Recent submissions

Now showing items 121-140 of 1970

    • Global health electives: Ethical engagement in building global health capacity 

      Visser, Adriena De; Hatfield, Jennifer; Ellaway, Rachel; Buchner, Denise; Seni, Jeremiah; Arubaku, Wilfred; Najjuma, Josephine Nambi; Hollaar, Gwendolyn (Medical Teacher, 2020)
      Purpose: Little is known about the impact medical trainees undertaking global health electives (GHEs) have on host institutions and their communities in low-and middle-income countries. The goal of this study was to explore ...

    • Diagnostic performance of fecal Helicobacter pylori antigen test in Uganda 

      Owot, Jacob Canwat; Tuhumwire, Caleb; Tumuhimbise, Christine; Tusiime, Florence; Emmanuel, Byaruhanga; Lumori, Boniface A. E.; Okello, Samson (BMC gastroenterology, 2022)
      We evaluated the diagnostic performance of a qualitative stool antigen test (SAT) in individuals with dyspepsia in rural Uganda using the polymerase chain reaction-based 16S ribosomal RNA assay (16S rRNA) for nucleotide ...

    • CD4-T-Lymphocyte Reference Ranges in Uganda and Its Influencing Factors 

      Nanzigu, Sarah; Waako, Paul; Petzold, Max; Kiwanuka, Gertrude; Dungu, Henry; Makumbi, Fred; Gustafsson, Lars L.; Eriksen, Jaran (Laboratory Medicine, 2011)
      Background: Given the importance of CD4-T-lymphocyte monitoring in HIV/ART management, we established CD4/CD8 reference ranges in Uganda and studied factors associated with CD4/CD8 in a normal population. Methods: Blood ...

    • Asymptomatic Plasmodium Infections in Children in Low Malaria Transmission Setting, Southwestern Uganda 

      Roh, Michelle E.; Oyet, Caesar; Orikiriza, Patrick; Wade, Martina; Kiwanuka, Gertrude N.; Mwanga-Amumpaire, Juliet; Parikh, Sunil; II, Yap Boum (Emerging infectious diseases, 2016)
      Asurvey of asymptomatic children in Uganda showed Plasmodium malariae and P. falciparum parasites in 45% and 55% of microscopy-positive samples, respectively. Although 36% of microscopy-positive samples were negative by ...

    • Prevalence and factors associated with inappropriate anti- diabetic medication therapy among type 2 diabetes mellitus patients at the medical and surgical wards of Mbarara Regional Referral Hospital, Uganda 

      Nigussie, Konjit Abebe; Shegena, Efrata Ashuro; Stephen, Obwoya Paul; Namugambe, Juliet Sanyu; Yadesa, Tadele Mekuriya (Plos one, 2022)
      Background: Inappropriate Anti-Diabetic Medication Therapy (IADT) refers to a drug-related problem and includes ‘ineffective drug therapy’, ‘unnecessary drug therapy’, ‘dosage too high’, and ‘dosage too low’. This study ...

    • Exploring Effective Approaches: Integrating Mental Health Services into HIV Clinics in Northern Uganda 

      Kabunga, Amir; Namata, Halimah; Kigongo, Eustes; Musinguzi, Marvin; Tumwesigye, Raymond; Auma, Anna Grace; Nabaziwa, Jannat; Shikanga, Enos Mwirotsi; Okalo, Ponsiano; Nalwoga, Viola; Udho, Samson (HIV/AIDS-Research and Palliative Care, 2024)
      Background: Integrating mental health services into HIV clinics is recognized as a promising strategy. However, the literature reveals gaps, particularly in the unique context of Northern Uganda, where factors such as ...

    • Evaluation of the Mutagenic Potential of Artavol® Using the Ame’s Test 

      Oloro, Joseph; Kasazza, Kennedy; P’okello, Oscar Okidi; Mucunu, James M.; Maitho, Timothy E.; Ganafa, Amon A. (European Journal of Medicinal Plants, 2024)
      Background: The worldwide increase in the use of herbal medicinal - products calls for their safety testing to protect the public from unintended hazardous effects. However, most are not tested, putting the public at risk. ...

    • Association between biomarkers of inflammation and dyslipidemia in drug resistant tuberculosis in Uganda 

      Baluku, Joseph Baruch ; Nalwanga, Robinah ; Kazibwe, Andrew ;  Olum, Ronald; Nuwagira, Edwin ;  Mugenyi, Nathan; Mulindwa, Frank ;  Bongomin, Felix (Lipids in Health and Disease, 2024)
      Background: Active tuberculosis (TB) significantly increases the risk of cardiovascular disease, but the underlying mechanisms remain unclear. This study aimed to investigate the association between inflammation biomarkers ...

    • Spectrum and Trends of Cancer in Southwestern Uganda from 2012 to 2021 

      Mitala, Yekosani; Atwine, Raymond; Ssenkumba, Brian; Birungi, Abraham; Tuhamize, Barbra; Ezinga, Richard; Male, Keneth; Taseera, Kabanda (EA Health Research Journal, 2024)
      Background: Cancer has become a global public health challenge and the number one cause of premature death. The incidence is increasing globally and more rapidly in low and middle-income countries despite the gross ...

    • Comparison of Starch from Locally Grown Food Crops as a Pharmaceutical Excipient: A Systematic Review 

      Reagan, Kikweranono Ronald; Jonans, Tusiimire (African Journal of Pharmaceutical Sciences, 2024)
      Starch is a widely used material with various applications in many starch based industries like pharmaceuticals, food and textiles, breweries and distillers due to its adhesive, gelling, thickening, swelling and film forming ...

    • Acceptability and feasibility of long-term, realtime electronic adherence monitoring of HIV pre-exposure prophylaxis (PrEP) use among young women in Kenya: A mixed methods study 

      Ogello, Vallery A.; Rono, Bernard Kipkoech; Ngure, Kenneth; Sedah, Eric; Thuo, Nicholas B; Musinguzi, Nicholas; Baeten, Jared M.; Bukusi, Elizabeth A.; Mugo, Nelly R.; Haberer, Jessica E. (PloS one, 2024)
      Real-time electronic adherence monitoring involves “smart” pill boxes that record and monitor openings as a proxy for pill taking and may be useful in understanding and supporting PrEP use; however, acceptability and/or ...

    • Challenges and fears of adolescents and young adults living with HIV facing transition to adult HIV care 

      Ashaba, Scholastic; Zanoni, Brian C.; Baguma, Charles; Tushemereirwe, Patricia; Nuwagaba, Gabriel; Kirabira, Joseph; Nansera, Denis; Maling, Samuel; Tsai, Alexander C. (AIDS and Behavior, 2023)
      Adolescents and young adults living with perinatally-acquired HIV (AYLPHIV) have poor outcomes along each step of the HIV care continuum due to challenges in seeking care and advocating for themselves. The transition from ...

    • Level of Knowledge on Sexual and Reproductive Health Rights Among the Teenage Mothers and Their Parents in Rwanda: A Comparative Cross-Sectional Study 

      Lutasingwa, Dan; Favina, Alain; Ochora, Moses; Rukanikigitero, Jean Marie Vianney; Gutabarwa, Louange Twahirwa; Kagaba, Aflodis; Kaggwa, Mark Mohan (Risk Management and Healthcare Policy, 2024)
      Background: Parents are the primary caregivers and influential figures in adolescents’ lives. They play a crucial role in shaping their children’s attitudes, beliefs, and behaviors regarding sexual reproductive health. A ...

    • Prediction models for post-discharge mortality among under-five children with suspected sepsis in Uganda: A multicohort analysis 

      Wiens, Matthew O.; Nguyen, Vuong; Bone, Jeffrey N.; Kumbakumba, Elias; Businge, Stephen; Tagoola, Abner; Sherine, Sheila Oyella; Byaruhanga, Emmanuel; Ssemwanga, Edward; Barigye, Celestine; Nsungwa, Jesca; Olaro, Charles; Ansermino, Mark; Kissoon, Niranjan; Singer, Joel; Larson, Charles P.; Lavoie, Pascal M.; Dunsmuir, Dustin; Moschovis, Peter P.; Novakowski, Stefanie; Komugisha, Clare; Tayebwa, Mellon; Mwesigwa, Douglas; Knappett, Martina; West, Nicholas; Mugisha, Nathan Kenya; Kabakyenga, Jerome (PLOS Global Public Health, 2024)
      In many low-income countries, over five percent of hospitalized children die following hospital discharge. The lack of available tools to identify those at risk of post-discharge mortality has limited the ability to make ...

    • Cryptococcal Meningitis and Clinical Outcomes in Persons With Human Immunodeficiency Virus: A Global Vie 

      Person, Anna K.; Crabtree-Ramirez, Brenda; Kim, Ahra; Veloso, Valdiléa; Maruri, Fernanda; Wandeler, Gilles; Fox, Matthew; Moore, Richard; Gill, M. John; Imran, Darma; Nguyen, Kinh Van; Nalitya, Elizabeth; Muyindike, Winnie; Shepherd, Bryan E.; McGowan, Catherine C. (Clinical Infectious Diseases, 2023)
      Background: Cryptococcal meningitis (CM) is a major cause of morbidity and mortality in persons with human immunodeficiency virus (HIV; PWH). Little is known about CM outcomes and availability of diagnostic and treatment ...

    • Adverse childhood events and self-harming behaviours among individuals in Ontario forensic system: the mediating role of psychopathy 

       Kaggwa, Mark Mohan; Chaimowitz, Gary A. ;  Erb, Bailea; Moulden, Heather ; Prat, Sebastien ; Davids, Arianna ;  Olagunju, Andrew T. (BMC Psychiatry, 2024-05-01)
      Background: Adverse childhood events (ACEs), psychopathy, and self-harming behaviours are prevalent among individuals in the forensic psychiatry system. While existing literature suggests that ACEs, self-harm, and psychopathy ...

    • Access to family planning services and associated factors among young people in Lira city northern Uganda 

      Kigongo, Eustes ; Tumwesigye, Raymond ;  Anyolitho, Maxson Kenneth; Musinguzi, Marvin ;  Kwizera, Gad; Achan, Everlyne ; Nabasirye, Caroline Kambugu ;  Udho, Samson; Kabunga, Amir ; Omech, Bernard  (BMC Public Health, 2024)
      Background: Access to family planning services among young people is crucial for reproductive health. This study explores the access and associated factors among young people in Lira City, Northern Uganda. Methods and ...

    • Association between HIV Serostatus and premalignant cervical lesions among women attending a cervical cancer screening clinic at a tertiary care facility in southwestern Uganda: a comparative cross-sectional study 

       Kirabira, Justus; Kayondo, Musa ;  Bawakanya, Stephen Mayanja; Nsubuga, Edirisa Juniour ; Yarine, Fajardo ; Namuli, Alexcer ; Namugumya, Rita ; Natulinda, Christine Hilda ;  Atwine, Raymond; Birungi, Abraham ; Lugobe, Henry Mark ; Tibaijuka, Leevan ; Kisombo, Dean ; Jjuuko, Mark ;  Agaba, David Collins; Saturday, Pascal ;  Atupele, Subira Mlangwa; Tumusiime, Matthew ; Migisha, Richard ;  Kajabwangu, Rogers (BMC Women's Health, 2024)
      Background: Uganda has approximately 1.2 million people aged 15–64 years living with human immunodeficiency virus (HIV). Previous studies have shown a higher prevalence of premalignant cervical lesions among HIV-positive ...

    • Pityriasis rosea: dermoscopic features in Uganda 

      Kiptis, Paul K.; Mirembe, Stephen K.; Aloyomola, Gladys; Mulyowa, Grace K. (International Journal of Dermatology, 2024)
      Purpose: The study aimed to describe the dermoscopic features of pityriasis rosea among patients attending the skin clinic at Mbarara Regional Referral Hospital. Patients and methods: A hospital-based cross-sectional ...

    • Cucumeropsis mannii seed oil protects against bisphenol A-induced hepatotoxicity by mitigating inflammation and oxidative stress in rats 

      Aja, Patrick Maduabuchi; Chukwu, Chinecherem Adanna; Ugwu, Okechukwu Paul-Chima; Ale, Boniface Anthony; Agu, Peter Chinedu; Deusdedi, Tusubira; Chukwu, Darlington C.; l Ani, Onyedika Gabrie; Ekpono, Ezebuilo Ugbala; Ogwoni, Hilary Akobi; Awoke, Joshua Nonso; Ogbu, Patience N.; Aja, Lucy; Ukachi, Oliver Ugochukwu; Orji, Obasi Uche; Nweke, Chinoso Peter; Egwu, Chinedu; Ekpono, Ejike Ugbala; Ewa, Gift Onyinyechi; et al (RPS Pharmacy and Pharmacology Reports, 2024)
      Objectives: This study looked at how Cucumeropsis mannii seed oil (CMSO) affected male Wistar albino rats’ liver damage caused by bisphenol A (BPA). Methods: The standard HPLC method was used to assess the CMSO’s ...