Faculty of Medicine: Recent submissions
Now showing items 681-700 of 1988
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Magnitude and predictors of pre-referral treatment by Community Health Workers practicing in Rural South Western Uganda: A cross sectional study
(Research square, 2023)Background: Pre-referral treatment is critical for management of childhood illnesses. Under iCCM strategy, community health workers (CHWs) give pre-referral treatment to children under five years of age with danger signs. ... -
Evaluation of the effect of Artemisia Annua L. and Moringa Oleifera Lam. on CD4 count and viral load among PLWH on HAART at Mbarara Regional Referral Hospital: A Double-Blind Randomized Controlled Clinical Trial
(Research square, 2022)Background: Initiation of HAART among people living with HIV (PLWH) having a CD4 count ≤ 350cells/μl, produces poor immunological recovery, putting them at a high risk of opportunistic infections. Artemisia annua and Moringa ... -
Esophageal foreign body retrieved by cervical esophagotomy four years after ingestion
(Journal of Pediatric Surgery Case Reports, 2023)Background: Foreign body ingestion is common pediatric population with more than 55% from ingestion of coins. Over 80% pass spontaneously through the digestive tract, but substantial amount lodge in the UES causing esophageal ... -
Correction: Gender differences among patients with drug resistant tuberculosis and HIV co‑infection in Uganda: a countrywide retrospective cohort study
(BMC Infectious Diseases, 2023)Following publication of the original article [1], the authors identified an error in the author name of Anna M. Stadelman. Additionally, the ORCID number was previously unavailable. The incorrect author name is: Anna ... -
Behavioral and Psychological Symptoms of Dementia: Prevalence, Symptom Severity, and Caregiver Distress in South-Western Uganda—A Quantitative Cross-Sectional Study
(International Journal of Environmental Research and Public Health, 2023)The purpose of the study was to investigate behavioral and psychological symptoms (BPSD) prevalence, severity, and distress experienced by caregivers of people living with dementia (PLWD). A cross-sectional, population-based ... -
Associations of the COVID-19 pandemic with quality of life: A cross-sectional study of older-age people with and without HIV in rural Uganda
(Journal of Global Health, 2023)Background: COVID-19-related lock¬downs and other public health mea¬sures may have differentially affected the quality of life (QOL) of older peo¬ple with and without human immuno¬deficiency virus (HIV) in rural Uganda. ... -
Aflatoxin Susceptible Food Consumption Frequency, Prevalence, and Levels in Household Foodstuffs in Southwestern Uganda
(Journal of Food Quality, 2023)Contamination of household foodstu1s by a2atoxins has been associated with many illnesses, especially hepatocellular cancer and malnutrition. A2atoxins are toxins produced by fungi, especially Aspergillus 1avus and Aspergillus ... -
ADMET profiling and molecular docking of potential antimicrobial peptides previously isolated from African catfish, Clarias gariepinus
(Frontiers in Molecular Biosciences, 2022)Amidst rising cases of antimicrobial resistance, antimicrobial peptides (AMPs) are regarded as a promising alternative to traditional antibiotics. Even so, poor pharmacokinetic profiles of certain AMPs impede their utility ... -
Acute and Sub-Acute Toxicity Study of Ethanolic Crude Extract of Mitracarpus hirtus Plant on Wistar Rats
(International Journal of Science and Healthcare Research, 2017)Background: Plants are still considered among the important source of bioactive compound, especially in traditional medicine that has been used for centuries. Ethno botanical survey showed that Mitracarpus hirtus is used ... -
Leave no one behind: response to new evidence and guidelines for the management of cryptococcal meningitis in low-income and middle-income countries
(The Lancet infectious diseases, 2019)In 2018, WHO issued guidelines for the diagnosis, prevention, and management of HIV-related cryptococcal disease. Two strategies are recommended to reduce the high mortality associated with HIV-related cryptococcal meningitis ... -
How Does Antiretroviral Treatment Attenuate the Stigma of HIV? Evidence from a Cohort Study in Rural Uganda
(AIDS and Behavior, 2013)Program implementers and qualitative researchers have described how increasing availability of HIV antiretroviral therapy (ART) is associated with improvements in psychosocial health and internalized stigma. To determine ... -
Effect of systematic tuberculosis detection on mortality in young children with severe pneumonia in countries with high incidence of tuberculosis: a stepped-wedge clusterrandomised trial
(The Lancet Infectious Diseases, 2022)Background: Tuberculosis diagnosis might be delayed or missed in children with severe pneumonia because this diagnosis is usually only considered in cases of prolonged symptoms or antibiotic failure. Systematic tuberculosis ... -
Validation of the Safety Attitudes Questionnaire for Assessing Patient Safety Culture in Critical Care Settings of Three Selected Ugandan Hospitals
(Drug, Healthcare and Patient Safety, 2023)Background: The safety attitudes questionnaire (SAQ) short form (2006) is important for assessing patient safety culture in clinical environments. However, little is known about its validity and applicability in Uganda. ... -
Involvement and burden of informal caregivers of patients with mental illness: the mediating role of affiliated stigma
(BMC psychiatry, 2023)Background: The fear and lack of understanding of mental illness can lead to stigma. The stigma of mental illness affects not only individuals who suffer from it, but also the caregivers. Stigma among caregivers can lead ... -
High Mobility Group Box 1 (HMGB1) and HIV-Associated Kaposi’s Sarcoma in Africa
(Academia.edu, 2015)Other than Kaposi’s sarcoma-associated herpesvirus (KSHV) and CD4+ T cell lymphopenia, the mechanisms responsible for KS are poorly understood. Additional mechanisms must exist in sub-Saharan Africa given that only a ... -
Causal impact of malnutrition on mortality among adults hospitalized for medical illness in sub-Saharan Africa: what is the role of severe sepsis?
(BMC Nutrition, 2015)Background: In sub-Saharan Africa, malnutrition is associated with mortality in adults hospitalized for medical illness. However, it remains unclear whether this association is causal, and if causal, what the potential ... -
HIV-Associated Cryptococcal Meningitis Occurring at Relatively Higher CD4 Counts
(The Journal of infectious diseases, 2019)Background: Cryptococcal meningitis can occur in persons with less-apparent immunosuppression. We evaluated clinical characteristics and outcomes of persons with HIV-related Cryptococcus presenting with higher CD4 ... -
Perceived barriers and facilitators to antiretroviral therapy adherence among youth aged 15-24 years at a regional HIV clinic in SouthWestern Uganda: a qualitative study
(African Health Sciences, 2022)Introduction: South-Western region has the second highest HIV prevalence in Uganda. Youth aged 15-24 have shown poor adherence to antiretroviral therapy compared to the older cohorts. Previous studies from other regions ... -
Diagnostic and Prognostic Value of Cerebrospinal Fluid Lactate and Glucose in HIV-Associated Tuberculosis Meningitis
(Microbiology Spectrum, 2022)The role of cerebrospinal fluid (CSF) lactate in tuberculosis meningitis (TBM) diagnosis and prognosis is unclear. The aim of this study was to evaluate the performance of CSF lactate alone and in combination with CSF ... -
Intensified tuberculosis treatment to reduce the mortality of HIV‑infected and uninfected patients with tuberculosis meningitis (INTENSE‑TBM): study protocol for a phase III randomized controlled trial
(2022)Background: Tuberculous meningitis (TBM) is the most lethal and disabling form of tuberculosis (TB), particularly in sub-Saharan Africa. Current anti-TB treatment is poorly effective since TBM mortality reaches 40% in ...