Department of Pharmacy: Recent submissions
Now showing items 141-160 of 188
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Pharmacology, phytochemistry, and toxicity profiles of phytolacca dodecandra L’Hér
(Infectious Diseases: Research and Treatment, 2020)Introduction: Phytolacca dodecandra L’Hér. is a native plant of sub-Saharan Africa and Madagascar which is traditionally used for various ailments. Concerned with the scope of the available evidence, we designed a scoping ... -
Pharmacological reflection of plants traditionally used to manage diabetes mellitus in Tanzania
(Journal of Ethnopharmacology, 2020-12-25)Ethnopharmacological relevance: The increasing national prevalence of diabetes mellitus (DM) and its complications have overstretched the health care system in Tanzania and influenced patients to use herbal medicines as ... -
Pharmacognostic, antiplasmodial and antipyretic evaluation of the aqueous extract of Vernonia amygdalina leaf
(Int. J. Biol. Chem. Sci., 2011)The impeding safety challenges to the use of herbs have made qualitative and quantitative evaluation of herbal preparations a necessity. This study was aimed at evaluating the pharmacognostic and pharmacological properties ... -
Effect of high-dose rifampicin on efavirenz pharmacokinetics: drug–drug interaction randomized trial
(Journal of Antimicrobial Chemotherapy, 2020-01)Background: High-dose rifampicin is considered to shorten anti-TB treatment duration but its effect on antiretroviral metabolism is unknown. Objectives: To assess the effect of doubling the rifampicin dose (to 20 mg/kg/day, ... -
Efficacy of Commercially Used Antibacterial Agents against Oral Bacteria Associated with HIV/AIDS Patients in South Western Uganda
(British Journal of Pharmaceutical Research, 2017-05)Aims: This was to determine efficacy and resistance profiles against commonly used commercial antibacterial agents in Uganda in the management of oral pathogens in HIV/AIDS patients. Study Design: This was an experimental ... -
Drugs in Clinical Practice from Toxic Plants and Phytochemicals
(Poisonous Plants and Phytochemicals in Drug Discovery, 2020) -
Resistance, Minimum Inhibitory and Bactericidal Concentration Profiles of Oral Bacteria from HIV/AIDS Patients in South Western Uganda
(British Journal of Medicine & Medical Research, 2016)Background: The development of drug resistance is a major challenge in the management of microbial infections especially in immune-compromised (HIV/AIDS) patients. Objective: This was to assess levels of antibacterial ... -
Resistance pattern of infected chronic wound isolates and factors associated with bacterial resistance to third generation cephalosporins at Mbarara Regional Referral Hospital, Uganda
(Plos one, 2021)Background The objectives of this study were; (I) to determine the proportion of pathogens isolated from patients with infected chronic wounds in the surgical ward of MRRH that are resistant to the third-generation ... -
Dried-leaf Artemisia annua: A practical malaria therapeutic for developing countries?
(World journal of pharmacology, 2014-12)Artemisinin from the plant Artemisia annua (A. annua) L, and used as artemisinin combination therapy (ACT), is the current best therapeutic for treating malaria, a disease that hits children and adults especially in ... -
Documentation and Phytochemical Screening of Most Commonly used Nutri-Medicinal Plants by Pregnant Women in Kyeizooba, Bushenyi District, Western Uganda
(Journal of Pharmacognosy & Natural Products, 2020-01)Nutri-medicinal plants are widely used as a remedy for some ailments among pregnant women worldwide. There are different medicinal plants used by pregnant women in Uganda depending on the culture and knowledge of these ... -
Dioscorea bulbifera, a highly threatened African medicinal plant, a review
(Cogent Biology, 2019-06)Dioscorea bulbifera bulbils are used in the treatment of Piles, dysentery, syphilis, ulcers, cough, leprosy, diabetes, asthma, and cancer. It is a raw material for contraceptives, and it is one of the most consumed yam ... -
Quality Control for the Safety of Natural Products
(Poisonous Plants and Phytochemicals in Drug Discovery, 2020)The World Health Organization (WHO) has defined a medicinal plant as any plant in which one or more of its parts consists of substances that are used for the synthesis of beneficial drugs [1]. These plants need to be studied ... -
Prevalence, characteristics and predicting risk factors of adverse drug reactions among hospitalized older adults: A systematic review and meta-analysis
(SAGE Open Medicine, 2021)Background: Occurrence of adverse drug reactions is a major global health problem mostly affecting older adults. Identifying the magnitude and predictors of adverse drug reactions is crucial to developing strategies to ... -
Registration and local production of essential medicines in Uganda
(Journal of pharmaceutical policy and practice, 2020)Background: Universal access to high quality essential medicines is critical to sustainable development (SDG 3.8). However low- and middle-income countries struggle to ensure access to all medicines on their national ... -
In vitro anti-tuberculous study on the combination of extracts of stem-bark of Erythrina abyssinica Lam. ex DC and conventional drugs
(Journal of Pharmacognosy and Phytochemistry, 2019)Background: Tuberculosis (TB) caused by Mycobacterium tuberculosis remains an important public health issue worldwide and TB patients are reported to use conventional drugs concurrently with medicinal plants. This study ... -
Development and validation of a revised instrument to measure burden of long-term medicines use: the Living with Medicines Questionnaire version 3
(Patient Related Outcome Measures, 2018)Methods: New statements were developed and validated through cognitive interviews with medicine users, and these and a global visual analog scale (VAS) were added to the 42-item LMQ-2. Construct validity was assessed ... -
Formulation, Development and Validation of a Wound Healing Herbal Ointment from Extracts of Bidens pilosa and Aloe barbadensis
(Journal of Pharmacy and Pharmacology Research, 2018)Various studies have been done to assess the wound healing potential of Aloe barbadensis and Bidens pilosa. Plant materials/ extracts that have been used in most of those studies have shown superior/ comparable efficacy ... -
Factors Affecting the Use of Nutri-Medicinal Plants by Pregnant Women in Kyeizooba, Bushenyi District Western Uganda
(Journal of Pharmacognosy & Natural Products, 2020)The use of nutri-medicinal plants is widely spread in the treatment of several ailments among pregnant women worldwide. In Uganda, different medicinal plants are used by pregnant women for treatment of different ailments. ... -
The safety and efficacy of Momordica charantia L. in animal models of type 2 diabetes mellitus: A systematic review and meta-analysis
(Phytotherapy Research, 2021)Type 2 diabetes mellitus is a chronic hyperglycemic condition due to progressively impaired glucose regulation. Momordica charantia L. could potentially improve hyperglycemia because its fruit extracts can alleviate insulin ... -
Evaluation of the adverse effects of Dracaena steudneri Engl. stem bark aqueous extract in Wistar rats
(African Journal of Pharmacy and Pharmacology, 2021)Safety of medicinal plants/products is one of the major areas that require more attention because of the high rate at which consumers use medicinal plants/products due to their availability and accessibility. Dracaena ...