Department of Internal Medicine: Recent submissions
Now showing items 61-80 of 258
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Patient-provider experiences with chronic non-communicable disease care during COVID-19 lockdowns in rural Uganda: A qualitative analysis
(Plos one, 2023)Non-communicable diseases (NCDs) are a growing health burden in Sub-Saharan Africa and especially Uganda, where they account for over one third of all deaths. During the COVID-19 pandemic, public health control measures ... -
Standard of care in advanced HIV disease: review of HIV treatment guidelines in six sub-Saharan African countries
(AIDS Research and Therapy, 2023)Background: The World Health Organization (WHO) recommends an evidence-based package of care to reduce mortality and morbidity among people with advanced HIV disease (AHD). Adoption of these recommendations by national ... -
Factors Associated with Chronic Obstructive Pulmonary Disease: A Hospital-Based Case–Control Study
(International Journal of Chronic Obstructive Pulmonary Disease, 2023)Purpose: Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality worldwide. In this paper, we determined risk factors for COPD among patients presenting to pulmonology and medical ... -
Real-time electronic adherence monitoring plus follow-up improves adherence compared with standard electronic adherence monitoring
(Aids, 2017)The impact of real-time electronic monitoring on antiretroviral therapy adherence warrants further study. We conducted an analysis of cohort participants that initially involved standard electronic adherence monitoring ... -
Determinants of delivery site's preferences among women in East Africa: case study in Ishaka municipality, Western Uganda
(PAMJ-One Health, 2020)Introduction: It has acknowledged that delivered at traditional birth attendance can increase mortality death. Epidemiological studies have identified poor quality of care as being at greater risk of increasing the home ... -
Highly Active Antiretroviral Therapy and Increased Use of Contraceptives Among HIV-Positive Women During Expanding Access to Antiretroviral Therapy in Mbarara, Uganda
(Andia, I., Kaida, A., Maier, M., Guzman, D., Emenyonu, N., Pepper, L., ... & Hogg, R. S. (2009). Highly active antiretroviral therapy and increased use of contraceptives among HIV-positive women during expanding access to antiretroviral therapy in Mbarara, Uganda. American journal of public health, 99(2), 340-347., 2009)Objectives: We investigatedwhether the prevalence of contraceptive use among women who are HIV positive varied according to use of highly active antiretroviral therapy (HAART) in Mbarara, Uganda. Methods: We used data ... -
Antiretroviral Therapy is Associated with Increased Fertility Desire, but not Pregnancy or Live Birth, among HIV+ Women in an Early HIV Treatment Program in Rural Uganda
(AIDS and Behavior, 2009)To assess the association between antiretroviral therapy (ART) and fertility history and desire among HIV positive Ugandan women, we conducted a cross-sectional study among HIV-positive Ugandan women aged 18– 50 years who ... -
Clinical features, resistance patterns and treatment outcomes of drug-resistant extra-pulmonary tuberculosis: A scoping review
(Journal of Clinical Tuberculosis and Other Mycobacterial Diseases, 2023)Background: Drug-resistant tuberculosis (DR-TB) is a threat to tuberculosis (TB) control. Extra-pulmonary forms of DR-TB (DR-epTB) are not well characterized. This review summarizes the clinical features, resistance patterns ... -
Validation of heart failure quality of life tool and usage to predict all-cause mortality in acute heart failure in Uganda: the Mbarara heart failure registry (MAHFER)
(BMC cardiovascular disorders, 2018)Background: The health-related quality of life (HRQoL) is an important treatment goal that could serve as low-cost prognostication tool in resource poor settings. We sought to validate the Kansas City Cardiomyopathy ... -
Association between HIV and Prevalent Hypertension and Diabetes Mellitus in South Africa: analysis of a nationally representative cross-sectional survey
(International Journal of Infectious Diseases, 2022)Objectives: Cardiovascular diseases (CVD) burden is rising among persons living with HIV (PLWH) in sub-Saharan Africa. It is unclear whether this reflects absolute increase in HIV-related CVD risk or unmasking by improved ... -
Increasing use of interferon gamma release assays among children ≥2 years of age in a setting with low tuberculosis prevalence
(The Pediatric Infectious Disease Journal, 2022)US guidelines recommend interferon gamma release assays (IGRAs) for diagnosis of tuberculosis infection in children. In this retrospective cohort study, IGRA use in children 2–17 years of age increased substantially between ... -
Employers’ and Employees’ Perspectives of HIV Self-Testing at Male-Dominated Work Sites and Linkage to Posttest Services in Uganda
(The Journal of the Association of Nurses in AIDS Care, 2020)This study explored men’s views of workplace-based HIV self-testing and the barriers and facilitators of linkage to posttest services. Six focus group discussions and individual in-depth interviews were held with employers ... -
Concordance Between Point-of-Care Urine Ethyl Glucuronide Alcohol Tests and Self-Reported Alcohol Use in Persons with HIV in Uganda
(AIDS and Behavior, 2022)In regions with high rates of alcohol use and HIV and TB infections, to accurately screen and assess alcohol use to maximize positive treatment outcomes remains problematic. In this study, we examined the concordance between ... -
An analysis of stroke risk factors by HIV serostatus in Uganda: Implications for stroke prevention in sub-Saharan Africa
(Journal of Stroke and Cerebrovascular Diseases, 2022)Objective: HIV infection is an important stroke risk factor in sub-Saharan Africa. However, data on stroke risk factors in the era of antiretroviral therapy (ART) are sparse. We aimed to determine if stroke risk factors ... -
Outpatient Cryptococcal Antigen Screening Is Associated With Favorable Baseline Characteristics and Improved Survival in Persons With Cryptococcal Meningitis in Uganda
(Clinical Infectious Diseases, 2023)Background: It is unknown whether persons with symptomatic cryptococcal meningitis detected during routine blood cryptococcal antigen (CrAg) screening have better survival than persons presenting with overt meningitis. ... -
Persistently elevated intracranial pressure in cryptococcal meningitis– 76 therapeutic lumbar punctures
(Medical Mycology Case Reports, 2023)Cryptococcal meningitis still remains the most common form of adult meningitis in sub-Saharan Africa, due to the burden of HIV/AIDS. Increased intracranial pressure (ICP) is a major complication of cryptococcosis and ... -
Utilization of health insurance by patients with diabetes or hypertension in urban hospitals in Mbarara, Uganda
(PLOS Global Public Health, 2023)Background: Diabetes and hypertension are among the leading contributors to global mortality and require life-long medical care. However, many patients cannot access quality healthcare due to high out-of-pocket expenditures, ... -
Mycobacterium tuberculosis infection and cytogenetic abnormalities among people with HIV
(Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 2023)Objective: To compare cytogenetic abnormalities among people living with HIV (PLWH) with and without previous exposure to Mycobacterium tuberculosis (Mtb) (both latent tuberculosis infection [LTBI] and active tuberculosis ... -
Thirty-Day Outcomes of Young and Middle-Aged Adults Admitted with Severe COVID-19 in Uganda: A Retrospective Cohort Study
(Infection and Drug Resistance, 2023)Background: There is scarcity of data regarding young and middle-aged adults hospitalized with severe Corona Virus Disease 2019 (COVID-19) in Africa. In this study, we describe the clinical characteristics and 30-day ... -
Unfavorable treatment outcomes among patients with drugresistant TB in Uganda
(The International Journal of Tuberculosis and Lung Disease, 2023)Background: Drug-resistant TB (DR-TB) remains a significant public health burden and a threat to the progress made in TB control and prevention in sub- Saharan Africa. Objective: To determine the risk-predictors of poor ...
