Browsing Research Article by Issue Date
Now showing items 1-20 of 146
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Impact of Sex: Determination of Alcohol Neuroadaptation and Reinforcement
(ALCHOLISM,Clinical and experimental Research, 2006-01-25)his article represents the proceedings of a symposium at the Research Society on Alcoholism meeting in Santa Barbara, California. The organizers/chairs were Kristine M. Wiren and Deborah A. Finn. Following a brief introduction ... -
Influence of hormonal status on behavioral responses to an acute ethanol challenge during ethanol withdrawal in male and female rats
(Pharmacology, Biochemistry and Behavior, 2008)We previously reported significant sex differences in ethanol withdrawal (EW) recovery as well as in sensitivity to GABAA receptor modulators during EW. The aim of the present study was to determine if hormonal status ... -
Ethno medical knowledge and traditional use of Aristolochia bracteolata Lam. for malaria among local communities in Jubek State of South Sudan: A cross-sectional survey
(Journal of Ethnopharmacology, 2009)Ethnopharmacological relevance: The recognized challenges to access conventional antimalarial medicines could have contributed to the extensive use of Aristolochia bracteolata Lam. (Aristolochiaceae) to manage malaria in ... -
Infections
(African Health Sciences, 2011-09)Background: Medicinal plants in Uganda and other developing countries have been scientifically demonstrated to have medicinal benefits but few or none have been translated to products for clinical use. Most herbal products ... -
Concomitant herbal medicine and Antiretroviral Therapy (ART) use among HIV patients in Western Uganda: A cross-sectional analysis of magnitude and patterns of use, associated factors and impact on ART adherence
(AIDS Care, 2012)Use of herbal medicines among patients receiving Anti-Retroviral Therapy (ART) remains by far an un characterised phenomenon in Africa and Uganda specifically. We evaluated the use of herbal medicines among patients on ART ... -
Artemether-lumefantrine to treat malaria in pregnancy is associated with reduced placental haemozoin deposition compared to quinine in a randomized controlled trial
(Malaria journal, 2012-05)Background: Data on efficacy of artemisinin-based combination therapy (ACT) to treat Plasmodium falciparum during pregnancy in sub-Saharan Africa is scarce. A recent open label, randomized controlled trial in Mbarara, Uganda ... -
Aflatoxins metabolism, effects on epigenetic mechanisms and their role in carcinogenesis
(SciRes, 2013)Chronic consumption of aflatoxin-contaminated foods is a global problem in both developing and developed countries especially where there is poor regulation of their levels in foods. In the body, aflatoxins (AFBs) mainly ... -
Antipyretic and Antinociceptive Properties of the Aqueous Extract and Saponin from an Edible Vegetable- Vernonia Amygdalina Leaf
(African Journal of food, agriculture, nutrition and development, 2013)Vernonia amygdalina is commonly used for food and health purposes. The processing of the leaf for food is usually aimed at removing bitter tasting principles like saponins. This study was designed to determine the antipyretic ... -
Registration, procurement, distribution, and use of misoprostol in Uganda: an interview-based observational study
(The Lancet, 2013-10-20)Background: Poor access to essential medicines remains a barrier to improvement of health in low-income countries. The maternal mortality rate from post-partum haemorrhage (PPH) in Uganda is one of the highest in the world. ... -
Whole Plant Approaches to Therapeutic Use of Artemisia annua L. (Asteraceae)
(rtemisia annua - Pharmacology and Biotechnology, 2013-11-27)Long used as a therapeutic tea by the Chinese to treat fever, Artemisia annua is more recently being studied and used for eventual treatment for not only malaria, but also many other diseases. This chapter describes studies ... -
Dried-leaf Artemisia annua: A practical malaria therapeutic for developing countries?
(World journal of pharmacology,, 2014)Artemisinin from the plant Artemisia annua (A. annua) L., and used as artemisinin combination therapy (ACT), is the current best therapeutic for treating malaria, a disease that hits children and adults especially in ... -
Effects of aqueous root bark extract of Citropsis articulata (Swingle & Kellerman) on sexual function in male rats
(Academic Journals, 2014-11-11)About 80% of the world’s population uses herbal medicine for the treatment of various health conditions. Erectile dysfunction is one of the conditions commonly treated using traditional herbs on large scale. In this ... -
Dried-leaf Artemisia annua: A practical malaria therapeutic for developing countries?
(World journal of pharmacology, 2014-12)Artemisinin from the plant Artemisia annua (A. annua) L, and used as artemisinin combination therapy (ACT), is the current best therapeutic for treating malaria, a disease that hits children and adults especially in ... -
Variations in antimalarial components of Artemisia annua Linn from three regions of Uganda
(African Health Sciences, 2015)Introduction: Artemisia annua plant from the family Asteracea is a powerful antimalarial plant introduced to Uganda around 2003. In addition to the artemisinin component, the plant also contains flavonoids which work in ... -
Adverse drug reaction reporting among health care workers at Mulago National Referral and Teaching hospital in Uganda
(African Health Sciences, 2015)Background: Adverse Drug Reactions (ADRs) are an important contributor to patient morbidity and hospitalisation in Uganda. Under-reporting of ADRs may increase medicine-induced morbidity and mortality among patients. This ... -
Determination of the abortifacient activity of the aqueous extract of Phytolacca dodecandra (L’Her) leaf in Wistar rats
(African Journal of Pharmacy and Pharmacology, 2015)Throughout history women have tried to control their fertility using herbal remedies; traditionally Phytolacca dodecandra leaves have been used as an abortifacient. The objective of this study was to determine the ... -
Comparison of Antibacterial Activities of Fermented with those of Unfermented Annona muricata (L) Fruit Extracts
(International Journal for Microbiology and Applied sciences, 2015)Fermentation is known to enhance antibacterial activities of some plant products. The research aimed to compare the antibacterial activities of the fermented with those of unfermented fruits of Annona muricata, obtained ... -
Civil Society Organizations and medicines policy change: A case study of registration, procurement, distribution and use of misoprostol in Uganda
(Social Science & Medicine, 2015-02-18)Misoprostol use for postpartum haemorrhage (PPH) has been promoted by Civil Society Organizations (CSOs) since the early 2000s. Yet, CSOs' role in improving access to misoprostol and shaping health policy at global and ... -
Resistance to Cotrimoxazole and Other Antimicrobials among Isolates from HIV/AIDS and Non-HIV/AIDS Patients at Bugando Medical Centre, Mwanza, Tanzania
(Hindawi, 2015-05-22)acterial resistance has increased in the AIDS era and is attributed to the widespread use of cotrimoxazole prophylaxis against opportunistic infections in HIV/AIDS patients. In Tanzania, cotrimoxazole prophylaxis has been ... -
Evaluation of the Acute and Sub-chronic Toxicities of the Methanolic Stem Bark Extract of Spathodea campanulata (P. Beauv.) Bignoniacea
(British Journal of Pharmacology and Toxicology, 2016)Spathodea campanulata (P. Beauv.)Bignoniacea is widely used in Ugandan traditional medicine. The aim of this study was to carry out the acute and sub-chronic toxicity profile of its methanolic stem bark extract (SCE). A ...
