Browsing Research Article by Title
Now showing items 1-20 of 146
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Acute and repeated-dose toxicity of Echinops kebericho Mesfin essential oil
(Toxicology Reports, 2021)Echinops kebericho Mesfin is used for the management of various diseases and fumigation during child birth. This study investigated acute and repeated-dose toxicity of E. kebericho M. essential oils (EOs). The study was ... -
Acute and sub-acute oral toxicity of aqueous whole leaf and green rind extracts of Aloe vera in Wistar rats
(BMC complementary medicine and therapies, 2022)Background: Several local communities in Central, Western, Eastern, and Northern regions of Uganda have been using the whole leaf extracts of Aloe vera (L.) Burm. f. (Asphodelaceae) in the treatment of various ailments. ... -
Adverse drug reaction reporting among health care workers at Mulago National Referral and Teaching hospital in Uganda
(African Health Sciences, 2015)Background: Adverse Drug Reactions (ADRs) are an important contributor to patient morbidity and hospitalisation in Uganda. Under-reporting of ADRs may increase medicine-induced morbidity and mortality among patients. This ... -
Aflatoxins metabolism, effects on epigenetic mechanisms and their role in carcinogenesis
(SciRes, 2013)Chronic consumption of aflatoxin-contaminated foods is a global problem in both developing and developed countries especially where there is poor regulation of their levels in foods. In the body, aflatoxins (AFBs) mainly ... -
Analgesic Appraisal of Bidens pilosa (Asteraceae) Leaf Extracts Used in Management of Oral Lesion Pain in HIV/AIDS Patients in Rodents
(Pharmacology & Pharmacy, 2018)Oral lesions, diarrhoea, Pneumocystis carinii pneumonia, tuberculosis and urinary tract infections are some of the opportunistic infections (OIs) which arise when the CD4 cells of the HIV/AIDS patient fall below 200 ... -
Anti-ageing Activity and Antioxidant Activity of Methanol Extracts of Leaves and Flowers of Salvia officinalis and Rosmarinus officinalis
(Journal of Young Pharmacists, 2023)Background: In this present work, methanol extracts of the leaves and flowers of Salvia officinalis Linn. (MES) and Rosmarinus officinalis Linn. (MER) were examined for their potential anti-aging and antioxidant properties ... -
Anticancer potential of delphinidin and its derivatives: therapeutic and mechanistic insights
(Medicinal Chemistry Research, 2024)Anthocyanins are water-soluble naturally occurring flavonoids present in fruits, flowers, leaves, and roots of fruit plants and vegetables. One of the important anthocyanidin components of red wine and berries is delphinidin ... -
Anticonvulsant and anxiolytic activity of the leaf aqueous and ethanolic extracts of Melanthera scandens in a rat model
(HHS Public Access, 2016)Modern drug therapy of epilepsy is complicated by the inability of drugs to control seizures in some patients and side effects that range in severity from minimal impairment of the central nervous system to death from ... -
Antifungal activity of Cleome gynandra L. aerial parts for topical treatment of Tinea capitis: an in vitro evaluation
(Complementary and Alternative Medicine, 2016-07)Background: Cleome gynandra L. (Capparaceae) is an edible weed used in Uganda topically for its presumed antifungal activity against Tinea capitis. The goal of this study was to determine if this plant possesses antifungal ... -
Antimicrobial resistance and rational prescription practices: knowledge, perceptions and confidence of health profession interns in Uganda
(JAC-Antimicrobial Resistance, 2023)Background: Antimicrobial resistance (AMR) is significantly driven by misuse and overuse of antibiotics. Graduate health profession interns often prescribe antimicrobials under minimum supervision. Objectives: This study ... -
Antipyretic and Antinociceptive Properties of the Aqueous Extract and Saponin from an Edible Vegetable- Vernonia Amygdalina Leaf
(African Journal of food, agriculture, nutrition and development, 2013)Vernonia amygdalina is commonly used for food and health purposes. The processing of the leaf for food is usually aimed at removing bitter tasting principles like saponins. This study was designed to determine the antipyretic ... -
Antisickling effect of crude flavonoids in the methanolic leaf extract of Persea americana Mill
(Revista Cubana de Plantas Medicinales, 2019-06)Introduction: Sickle-cell anemia, a difficult-to-treat genetic disease, causes synthesis of abnormal hemoglobin in which erythrocytes assume a sickle shape and become susceptible to hemolysis. Research about Persea americana ... -
Appetite Suppressing Activity of Rumex Usambarensis Leaf and Stem Aqueous Extract in Wistar Albino Female Rats: an in vivo Experimental Study
(Journal of Experimental Pharmacology, 2024)Background: The burden of obesity and overweight associated morbidity and mortality is increasing in epidemic proportions worldwide. Suppression of appetite is one of the mechanisms that has been shown to reduce weight. ... -
Appetite Suppressing Activity of Rumex Usambarensis Leaf and Stem Aqueous Extract in Wistar Albino Female Rats: an in vivo Experimental Study
(Journal of Experimental Pharmacology, 2024)Background: The burden of obesity and overweight associated morbidity and mortality is increasing in epidemic proportions worldwide. Suppression of appetite is one of the mechanisms that has been shown to reduce weight. ... -
Appetite Suppressing Activity of Rumex Usambarensis Leaf and Stem Aqueous Extract in Wistar Albino Female Rats: an in vivo Experimental Study
(Journal of Experimental Pharmacology, 2024)Background: The burden of obesity and overweight associated morbidity and mortality is increasing in epidemic proportions worldwide. Suppression of appetite is one of the mechanisms that has been shown to reduce weight. ... -
Application of the herbal chemical marker ranking system (Herb MaRS) to the standardization of herbal raw materials: a case study
(BMC Complementary Medicine and Therapies, 2023)Introduction: Phytochemical standardization of herbal materials involves establishing consistent levels of one or more active ingredients or markers. It ensures the authenticity and quality of herbal materials, extracts, ... -
Artemether-lumefantrine to treat malaria in pregnancy is associated with reduced placental haemozoin deposition compared to quinine in a randomized controlled trial
(Malaria journal, 2012-05)Background: Data on efficacy of artemisinin-based combination therapy (ACT) to treat Plasmodium falciparum during pregnancy in sub-Saharan Africa is scarce. A recent open label, randomized controlled trial in Mbarara, Uganda ... -
Artemisia afra infusions clinical benefits as a complementary treatment to “WHO” approved drugs against tuberculosis
(Pharmacy & Pharmacology International Journal, 2022)In the past few years, the number of people infected with pulmonary tuberculosis has increased.1Today, it kills thousands in Africa alone, millions worldwide and the numbers keep on increasing due to COVID-19 (WHO, 2021). ... -
Artemisia annua L.- Vernonia amygdalina Del: A Potential Herbal Artemisinin Combination Treatment against Malaria
(British Journal of Pharmaceutical Research, 2016-01)Aim of Study: The aim of the study was to determine the potential of Vernonia amygdalina - Artemisia annual combination as a possible herbal artemisinin combination treatment of malaria. Place and Duration of Study: Study ... -
Association between Pre-Hospital Antibiotic Exposure and Level of Bacterial Resistance (PHAE Study): A Matched Case Control Study at the Medical and Paediatric wards of Mbarara Regional Referral Hospital-South Western Uganda
(Research square, 2022-09-07)Background: This study aimed to determine the association between pre-hospital antibiotic exposure and level of bacterial resistance among adult and paediatric patients. Methods: In the study, 79 antibiotic pre-exposed ...
