Department of Pharmacy: Recent submissions
Now showing items 41-60 of 182
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GC-FID and GC-MS profiling and in vitro antidiabetic and antioxidant activities of Chenopodium ambrosioides L.
(Natural Resources for Human Health., 2023)Chenopodium ambrosioides is widely used in traditional medicines to manage several health conditions. This study aimed to investigate the chemical composition of the n-hexane fraction and the in vitro antidiabetic and ... -
Variation of antioxidant and antibacterial activities of ethanolic extracts of propolis in three bee-keeping agro-ecological zones of Uganda
(African Journal of Pharmacy and Pharmacology, 2023)Propolis is a resinous plant material collected by bees to defend their colony. This study evaluated the antibacterial and antioxidant activities of ethanolic extracts of Ugandan propolis in three bee-keeping agro-ecological ... -
Microbial and physical evaluation of selected cough syrups sold at peripheral drug outlets in Bushenyi District, South Western Uganda
(African Journal of Pharmacy and Pharmacology, 2023)Syrups, being non-sterile liquid pharmaceutical formulations, are prone to microbial contamination. The most common microbial contaminants are bacteria and fungi. Contamination of oral liquid pharmaceuticals makes them ... -
Differences in Symptom Severity and Quality of Life among Patients with Cancer Using Conventional Therapies with/ without Herbal Medicines in Uganda: A Cross-Sectional Study
(Asian Pacific Journal of Cancer Prevention, 2023)Objective: Patients with cancer experience numerous symptoms related to cancer and treatment side effects that reduce their quality of life (QOL). Although herbal medicine (HM) is used to manage such symptoms by patients ... -
Application of the herbal chemical marker ranking system (Herb MaRS) to the standardization of herbal raw materials: a case study
(BMC Complementary Medicine and Therapies, 2023)Introduction: Phytochemical standardization of herbal materials involves establishing consistent levels of one or more active ingredients or markers. It ensures the authenticity and quality of herbal materials, extracts, ... -
Evaluation of antibiotic use among inpatients in surgical ward at Mbarara Regional Referral Hospital, South-Western Uganda
(Infectious Diseases Research, 2023)Objective: The main aim of this study was to evaluate antibiotic use among inpatients in surgical ward at South-Mbarara Regional Referral Hospital, South-Western Uganda. Methodology: A retrospective cross-sectional study ... -
Suberosin Alleviates Thiazolidinedione‑Induced Cardiomyopathy in Diabetic Rats by Inhibiting Ferroptosis via Modulation of ACSL4‑LPCAT3 and PI3K‑AKT Signaling Pathways
(Cardiovascular Toxicology, 2023)Thiazolidinediones are useful antidiabetic medications. However, their use is associated with adverse side effects like edema, heart failure and bone fractures. In this study, we investigated the anti-ferroptosis effects ... -
Anti-ageing Activity and Antioxidant Activity of Methanol Extracts of Leaves and Flowers of Salvia officinalis and Rosmarinus officinalis
(Journal of Young Pharmacists, 2023)Background: In this present work, methanol extracts of the leaves and flowers of Salvia officinalis Linn. (MES) and Rosmarinus officinalis Linn. (MER) were examined for their potential anti-aging and antioxidant properties ... -
Frequency, severity, and factors associated with clinically significant drug‑drug interactions among patients with cancer attending Mbarara Regional Referral Hospital Cancer Unit, Uganda
(BMC cancer, 2022)Background: Cancer is a major public health problem with pharmacotherapy being the cornerstone of its management. Cancer patients receive multiple drugs concurrently risking Drug-Drug Interactions (DDIs). DDIs, though ... -
Chemometric Classification of Mangifera indica L. Leaf Cultivars, Based on Selected Phytochemical Parameters; Implications for Standardization of the Pharmaceutical Raw Materials
(Evidence-Based Complementary and Alternative Medicine, 2023)Introduction: Mangifera indica leaves are among the most common materials employed in manufacturing herbal medicinal products. Despite the phytochemical variation of M. indica cultivars, there are no monographs to guide ... -
The meaning of caring for patients with cancer among traditional medicine practitioners in Uganda: A grounded theory approach
(PLOS Global Public Health, 2023)Traditional medicine practitioners (TMPs) are a critical part of healthcare systems in many sub-Saharan African countries and play vital roles in caring for patients with cancer. Despite some progress in describing TMPs’ ... -
The Toxicity and Abortifacient Studies of Commelina benghalensis Leaves and Stalk in Wistar Rats
(Acta Scientific Medical Sciences, 2022)Scope of this paper is of Pharmacological relevance. Introduction: The use of plants as a natural medicine has been attached to the culture of different ethnic groups and is practiced worldwide. Thus called traditional ... -
Ligand-protein interactions of plant-isolated (9z,12z)-octadeca-9,12-dienoic acid with B-ketoacyl-Acp synthase (KasA) in potential anti-tubercular drug designing
(Scientific African, 2020)Mycobacterium tuberculosis remains one of the world’s contributors to mortality. With the emergence of SARS-CoV-2 coinfections, patients with TB are predisposed to being more heavily weighed down by COVID-19 disease and ... -
Prevalence and factors associated with drug therapy problems among hypertensive patients at hypertension clinic of Mbarara Regional Referral Hospital, Uganda: a |cross-sectional study
(Therapeutic Advances in Cardiovascular Disease, 2023)Background: Despite the use of safe and effective conventional drugs, drug therapy problems (DTPs) pose a threat to the successful management of hypertension. DTPs are of a great concern in health care because of their ... -
High PrEP uptake and objective longitudinal adherence among HIV-exposed women with personal or partner plans for pregnancy in rural Uganda: A cohort study
(PLoS Medicine, 2023)Background: In Uganda, fertility rates and adult HIV prevalence are high, and many women conceive with partners living with HIV. Pre-exposure prophylaxis (PrEP) reduces HIV acquisition for women and, therefore, infants. ... -
Body composition of type 2 diabetes patients in Uganda: A case-control study
(Journal of public health in Africa, 2023)Introduction: The prevalence of obesity among people diagnosed with Type 2 Diabetes Mellitus (T2DM) has been widely documented. However, the specific composition of this bodyweight remains largely unknown. The study aimed ... -
Diversity of bacterial community in the rhizosphere and bulk soil of Artemisia annua grown in highlands of Uganda
(Plos one, 2023)High land areas in Uganda are suitable for the farming of Artemisia annua. However, harvested A. annua from these areas contain varying concentrations of antimalarial components. This may be attributed to variation in soil ... -
Comparison of the Wound Healing Activity of the Leaf and Leaf Ash Extracts of Vernonia amygdalina in Rats
(Research square, 2023)Background: Species in the genus Vernonia (Asteraceae) are traditionally used in the treatment of different ailments, for example, leaves in both fresh and dry forms have been used in dressing wounds. Anecdotal reports ... -
Evaluating the Feasibility, Acceptability, and Preliminary Efficacy of SupportMoms-Uganda, an mHealth-Based Patient-Centered Social Support Intervention to Improve the Use of Maternity Services Among Pregnant Women in Rural Southwestern Uganda: Randomized Controlled Trial
(JMIR Formative Research, 2023)Background: SMS text messaging and other mobile health (mHealth) interventions may improve knowledge transfer, strengthen access to social support (SS), and promote positive health behaviors among women in the perinatal ... -
Ethnobotanical Survey of Medicinal Plants Used in Breast Cancer Treatment by Traditional Health Practitioners in Central Uganda
(Journal of Multidisciplinary Healthcare, 2023)Purpose: The study aimed to document the existing knowledge and practices related to breast cancer recognition and treatment using medicinal plants by traditional health practitioners in Central Uganda. Methods: This ...