Research Articles: Recent submissions
Now showing items 161-180 of 445
-
Associations of the COVID-19 pandemic with quality of life: A cross-sectional study of older-age people with and without HIV in rural Uganda
(Journal of Global Health, 2023)Background: COVID-19-related lock¬downs and other public health mea¬sures may have differentially affected the quality of life (QOL) of older peo¬ple with and without human immuno¬deficiency virus (HIV) in rural Uganda. ... -
Attenuated HIV-1 Nef But Not Vpu Function in a Cohort of Rwandan Long-Term Survivors
(Frontiers in virology, 2022)HIV-1 accessory proteins Nef and Vpu enhance viral pathogenesis through partially overlapping immune evasion activities. Attenuated Nef or Vpu functions have been reported in individuals who display slower disease progression, ... -
Understanding the barriers and enablers for postgraduate medical trainees becoming simulation educators: a qualitative study
(BMC Medical Education, 2023)Introduction: There is increasing evidence that Simulation-based learning (SBL) is an effective teaching method for healthcare professionals. However, SBL requires a large number of faculty to facilitate small group sessions. ... -
Novel FujiLAM assay to detect tuberculosis in HIV-positive ambulatory patients in four African countries: a diagnostic accuracy study
(The Lancet Global Health, 2023)Background: Development of rapid biomarker-based tests that can diagnose tuberculosis using non-sputum samples is a priority for tuberculosis control. We aimed to compare the diagnostic accuracy of the novel Fujifilm SILVAMP ... -
Stigma of infidelity associated with condom use explains low rates of condom uptake: qualitative data from Uganda and Tanzania
(Reproductive Health, 2023)Despite widespread messaging supporting male (external) condom use to prevent HIV in endemic settings, utilization of condoms is low across sub-Saharan Africa. A thorough understanding of barriers to condom use as a form ... -
Contribution of community health workers to the treatment of common illnesses among under 5‑year‑olds in rural Uganda
(Malaria Journal, 2022)Background: The control of malaria, pneumonia, and diarrhoea is important for the reduction in morbidity and mortality among children under 5 years. Uganda has adopted the Integrated Community Case Management strategy using ... -
Prevalence of prediabetes and associated factors among community members in Rural Isingiro district
(Research square, 2022)Background: In rural Uganda many people are either pre-diabetic or diabetic, however they do not know that these conditions afflict them. The burden of pre-diabetes in rural Isingiro had not previously been determined. The ... -
Knowledge, attitude and perceptions of medical students towards mental health in a university in Uganda
(BMC Medical Education, 2022-10-20)Background: The prevalence of mental illness among medical students is high. A gap remains on what knowledge should be given to improve the attitudes and perceptions towards mental health. Despite the vast body of literature ... -
Testing for malaria does not cure any pain a qualitative study exploring low use of malaria rapid diagnostic tests at drug shops in rural Uganda
(PLOS Glob Public Health, 2022)The World Health Organization recommends all suspected malaria cases be confirmed with a parasitological test, typically a rapid diagnostic test (RDT), prior to treatment. Despite recommendations, many fevers presenting ... -
Neonatal Paenibacilliosis: Paenibacillus thiaminolyticus as a Novel Cause of Neonatal Sepsis with High Risk of Sequelae in Uganda
(medRxiv., 2022)Paenibacillus thiaminolyticus may be an underdiagnosed cause of neonatal sepsis. We prospectively enrolled a cohort of 800 neonates presenting with a clinical diagnosis of sepsis at two Ugandan hospitals. Quantitative ... -
Who Stays and Who Goes: Predictors of Admission among Patients Presenting with Febrile Illness and a Positive Malaria Rapid Diagnostic Test in a Rural Ugandan Health Center
(The American journal of tropical medicine and hygiene, 2018)Not much is known about clinical decision-making in rural, low-resource settings regarding fever, a common reason for presentation to care. In this prospective cohort study of patients presenting with febrile illness to a ... -
Where there is no doctor: can volunteer community health workers in rural Uganda provide integrated community case management?
(African health sciences, 2017)Introduction: Integrated community case management (iCCM) involves assessment and treatment of common childhood ill nesses by community health workers (CHWs). Evaluation of a new Ugandan iCCM program is needed. Objectives: ... -
Using blood pressure height index to define hypertension among secondary school adolescents in southwestern Uganda
(Journal of Human Hypertension, 2020)Hypertension is the number one risk factor for cardiovascular diseases worldwide and yet its diagnosis among adolescents, based on blood pressure percentiles which are age, height, and sex-specific, is complex. Our study ... -
Knowledge and Health Care Seeking Behaviours on Cancer of the Cervix among Rural Women- A Case Study of Isingiro District
(Journal of Health, Medicine and Nursing, 2015)Cervical cancer is an abnormal growth of cells in the cervical region of the uterus. Cancer of the cervix occurs when the cells of the cervix change in a way that leads to unregulated growth and invasion of other tissues ... -
Impact of rapid diagnostic tests for the diagnosis and treatment of malaria at a peripheral health facility in Western Uganda: an interrupted time series analysis
(Malaria journal, 2015)Background: The World Health Organization recommends that all suspected malaria cases receive a parasitological diagnosis prior to treatment with artemisinin-based combination therapy. A recent meta-analysis of clinical ... -
Effi cacy and safety of artemether–lumefantrine compared with quinine in pregnant women with uncomplicated Plasmodium falciparum malaria: an open-label, randomised, non-inferiority trial
(The Lancet infectious diseases, 2010)Background: Malaria in pregnancy is associated with maternal and fetal morbidity and mortality. In 2006, WHO recommended use of artemisinin-based combination treatments during the second or third trimesters, but data on ... -
Consumer Perspectives on a Pericoital Contraceptive Pill In India and Uganda
(International perspectives on sexual and reproductive health, 2013)Context: Studies suggest that women in some countries have adopted emergency contraceptive pills as a routine method of family planning. This practice indicates there may be latent demand for a pericoital contraceptive ... -
Anemia was an Uncommon Complication of Severe Malaria in a High-Transmission Rural Area of Western Uganda
(The American journal of tropical medicine and hygiene, 2018)The clinical epidemiology of severe malaria among patients presenting to peripheral health centers has not been well described. We conducted a prospective, observational cohort study to describe the epidemiology and clinical ... -
Rapid Diagnostic Tests to Guide Case Management of and Improve Antibiotic Stewardship for Pediatric Acute Respiratory Illnesses in Resource-Constrained Settings: a Prospective Cohort Study in Southwestern Uganda
(Microbiology spectrum, 2021)Pediatric acute respiratory illness (ARI) is one of the most common reasons for evaluation at peripheral health centers in sub-Saharan Africa and is frequently managed based on clinical syndrome alone. Although most ARI ... -
Ongoing long-lasting insecticide-treated net distribution efforts are 2 insufficient to maintain high rates of use among children in rural Uganda
(medRxiv, 2021)Background: Long-lasting insecticide-treated nets (LLINs) remain a cornerstone of malaria control, but optimal distribution strategies to sustain universal coverage are not well-defined Methods: We conducted a cross-sectional ...