Research Articles: Recent submissions
Now showing items 181-200 of 456
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Neonatal Paenibacilliosis: Paenibacillus thiaminolyticus as a Novel Cause of Neonatal Sepsis with High Risk of Sequelae in Uganda
(medRxiv., 2022)Paenibacillus thiaminolyticus may be an underdiagnosed cause of neonatal sepsis. We prospectively enrolled a cohort of 800 neonates presenting with a clinical diagnosis of sepsis at two Ugandan hospitals. Quantitative ... -
Who Stays and Who Goes: Predictors of Admission among Patients Presenting with Febrile Illness and a Positive Malaria Rapid Diagnostic Test in a Rural Ugandan Health Center
(The American journal of tropical medicine and hygiene, 2018)Not much is known about clinical decision-making in rural, low-resource settings regarding fever, a common reason for presentation to care. In this prospective cohort study of patients presenting with febrile illness to a ... -
Where there is no doctor: can volunteer community health workers in rural Uganda provide integrated community case management?
(African health sciences, 2017)Introduction: Integrated community case management (iCCM) involves assessment and treatment of common childhood ill nesses by community health workers (CHWs). Evaluation of a new Ugandan iCCM program is needed. Objectives: ... -
Using blood pressure height index to define hypertension among secondary school adolescents in southwestern Uganda
(Journal of Human Hypertension, 2020)Hypertension is the number one risk factor for cardiovascular diseases worldwide and yet its diagnosis among adolescents, based on blood pressure percentiles which are age, height, and sex-specific, is complex. Our study ... -
Knowledge and Health Care Seeking Behaviours on Cancer of the Cervix among Rural Women- A Case Study of Isingiro District
(Journal of Health, Medicine and Nursing, 2015)Cervical cancer is an abnormal growth of cells in the cervical region of the uterus. Cancer of the cervix occurs when the cells of the cervix change in a way that leads to unregulated growth and invasion of other tissues ... -
Impact of rapid diagnostic tests for the diagnosis and treatment of malaria at a peripheral health facility in Western Uganda: an interrupted time series analysis
(Malaria journal, 2015)Background: The World Health Organization recommends that all suspected malaria cases receive a parasitological diagnosis prior to treatment with artemisinin-based combination therapy. A recent meta-analysis of clinical ... -
Effi cacy and safety of artemether–lumefantrine compared with quinine in pregnant women with uncomplicated Plasmodium falciparum malaria: an open-label, randomised, non-inferiority trial
(The Lancet infectious diseases, 2010)Background: Malaria in pregnancy is associated with maternal and fetal morbidity and mortality. In 2006, WHO recommended use of artemisinin-based combination treatments during the second or third trimesters, but data on ... -
Consumer Perspectives on a Pericoital Contraceptive Pill In India and Uganda
(International perspectives on sexual and reproductive health, 2013)Context: Studies suggest that women in some countries have adopted emergency contraceptive pills as a routine method of family planning. This practice indicates there may be latent demand for a pericoital contraceptive ... -
Anemia was an Uncommon Complication of Severe Malaria in a High-Transmission Rural Area of Western Uganda
(The American journal of tropical medicine and hygiene, 2018)The clinical epidemiology of severe malaria among patients presenting to peripheral health centers has not been well described. We conducted a prospective, observational cohort study to describe the epidemiology and clinical ... -
Rapid Diagnostic Tests to Guide Case Management of and Improve Antibiotic Stewardship for Pediatric Acute Respiratory Illnesses in Resource-Constrained Settings: a Prospective Cohort Study in Southwestern Uganda
(Microbiology spectrum, 2021)Pediatric acute respiratory illness (ARI) is one of the most common reasons for evaluation at peripheral health centers in sub-Saharan Africa and is frequently managed based on clinical syndrome alone. Although most ARI ... -
Ongoing long-lasting insecticide-treated net distribution efforts are 2 insufficient to maintain high rates of use among children in rural Uganda
(medRxiv, 2021)Background: Long-lasting insecticide-treated nets (LLINs) remain a cornerstone of malaria control, but optimal distribution strategies to sustain universal coverage are not well-defined Methods: We conducted a cross-sectional ... -
Malaria prevalence and long-lasting insecticidal net use in rural western Uganda: results of a cross-sectional survey conducted in an area of highly variable malaria transmission intensity
(Malaria journal, 2021)Background: Long-lasting insecticidal nets (LLINs) remain a cornerstone of malaria control, but strategies to sustain universal coverage and high rates of use are not well-defined. A more complete understanding of ... -
Magnitude of Prior Teenage Pregnancy among Women Aged 18–67 Years in Rural Southwestern Uganda
(International Journal of TROPICAL DISEASE & Health, 2020)Objective: Teenage pregnancy is a growing health challenge among adolescents in Uganda with its magnitude varying across the different regions of Uganda. This study evaluated the magnitude and factors associated with prior ... -
Long-term quality of integrated community case management care for children in Bugoye Subcounty, Uganda: a retrospective observational study
(BMJ open, 2022)Objective: Integrated community case management (iCCM) of childhood illness in Uganda involves protocol based care of malaria, pneumonia and diarrhoea for children under 5 years old. This study assessed volunteer village ... -
Impact of rapid diagnostic tests for the diagnosis and treatment of malaria at a peripheral health facility in Western Uganda: an interrupted time series analysis
(Malaria journal, 2015)Background: The World Health Organization recommends that all suspected malaria cases receive a parasitological diagnosis prior to treatment with artemisinin-based combination therapy. A recent meta-analysis of clinical ... -
Immunogenicity and safety of fractional doses of yellow fever vaccines: a randomised, double-blind, non-inferiority trial
(The Lancet, 2021)Background: Stocks of yellow fever vaccine are insufficient to cover exceptional demands for outbreak response. Fractional dosing has shown efficacy, but evidence is limited to the 17DD sub strain vaccine. We assessed the ... -
HIV epidemic and cascade of care in 12 east African rural fishing communities: results from a population-based survey in Uganda
(BMC Public Health, 2020)Background: In East Africa, fishing communities are considered most-at-risk populations for the acquisition of HIV. We estimated HIV prevalence and assessed progress towards the UNAIDS 90–90-90 targets along the HIV treatment ... -
Gaps in measles vaccination coverage in Kasese district, Western Uganda: results of a qualitative evaluation
(BMC infectious diseases, 2022)Background: Despite the availability of a highly effective vaccine, measles remains a substantial public health problem in many countries including Uganda. In this study, conducted between June–August 2020 following a local ... -
Feasibility and acceptability of home-based HIV testing among refugees: a pilot study in Nakivale refugee settlement in southwestern Uganda
(BMC Infectious Diseases, 2018)Background: Refugees in sub-Saharan Africa face both the risk of HIV infection and barriers to HIV testing. We conducted a pilot study to determine the feasibility and acceptability of home-based HIV testing in Nakivale ... -
Factors Associated with Uptake of Immunizations for Vaccine-Preventable Childhood Diseases in a Peri-Urban Settlement; A Case Study of Nansana Municipality, Uganda
(Texila International Journal of Public Health, 2013)Immunization uptake for childhood vaccine-preventable diseases remains low in urban areas of Uganda, leading to repeated outbreaks of diseases like measles, despite easy communication and accessibility to services. The ...
