Research Articles: Recent submissions
Now showing items 201-220 of 445
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Challenges to achieving low palatal fistula rates following primary cleft palate repair: experience of an institution in Uganda
(BMC research notes, 2018)Objective: To determine frequency of palatal fistula following primary cleft palate repair and the associated factors as a measure of cleft palate repair outcome and its challenges at a cleft centre in Uganda. Results: ... -
Assessing Village Health Workers’ Ability to Perform and Interpret Rapid Diagnostic Tests for Malaria 4 Years after Initial Training: A Cross-Sectional Study
(The American Journal of Tropical Medicine and Hygiene, 2021)Village health workers (VHWs) in Bugoye subcounty, Uganda, provide integrated community case management (iCCM) care to children younger than 5 years for malaria, pneumonia, and diarrhea. We assessed the longevity of VHWs’ ... -
A novel CRISPR-based malaria diagnostic capable of Plasmodium detection, species differentiation, and drug-resistance genotyping
(BioMedicine, 2021)Background: CRISPR-based diagnostics are a new class of highly sensitive and specific assays with multiple applications in infectious disease diagnosis. SHERLOCK, or Specific High-Sensitivity Enzymatic Reporter UnLOCKing, ... -
A cross-sectional study comparing case scenarios and record review to measure quality of Integrated Community Case Management care in western Uganda
(Transactions of the Royal Society of Tropical Medicine and Hygiene, 2021)Background: In Integrated Community Case Management (iCCM), village health workers (VHW) assess and treat malaria, pneumonia and diarrhea using a clinical algorithm. Study objectives included: 1) Compare VHWs’ performance ... -
Defining High-risk Emergency Chief Complaints: Data-driven Triage for Low- and Middle-income Countries
(Academic Emergency Medicine, 2020)Objectives: Emergency medicine in low- and middle-income countries (LMICs) is hindered by lack of research into patient outcomes. Chief complaints (CCs) are fundamental to emergency care but have only recently been uniquely ... -
Adaptations to HIV services delivery amidst the COVID-19 pandemic restrictions in Kampala, Uganda: A qualitative study
(PLOS Glob Public Health, 2022)The enforcement of the coronavirus disease (COVID-19) pandemic restrictions disrupted health services delivery and currently, there is a limited understanding regarding measures employed by health facilities to ensure ... -
Low condom use at the last sexual intercourse among university students in sub-Saharan Africa: Evidence from a systematic review and meta-analysis
(PloS one, 2022)Background: There is inconsistent data about condom use at the last sexual intercourse (LSI) among university students in sub-Saharan Africa (SSA) and its association with sex, age, and condom negotiation efficacy. The ... -
Measles outbreak in Western Uganda: a case-control study
(BMC Infectious Diseases, 2021)Background: Measles outbreaks are prevalent throughout sub-Saharan Africa despite the preventive measures like vaccination that target under five-year-old children and health systems strengthening efforts like prioritizing ... -
Positive deviance for dual-method promotion among women in Uganda: study protocol for a cluster randomized controlled trial
(Trials, 2020)Background: Dual-method use is known as the most reliable protection against unintended pregnancies and sexually transmitted infections, including HIV. However, it is not commonly used in sub-Sharan Africa, especially among ... -
Socio-cultural and Economic Antecedents of Adolescent Sexual Decision-Making and HIV-Risk in Rural Uganda
(AIDS Care, 2013-02)With more than half of new infections occurring among youth, HIV/AIDS remains a major contributor to morbidity and mortality in Uganda. Semi-structured interviews were performed with 48 adolescents and 15 adult key informants ... -
Should community health workers offer support healthcare services to survivors of sexual violence? a systematic review
(BMC International Health and Human Rights, 2017)Background: Sexual violence is widespread, yet relatively few survivors receive healthcare or complete treatment. In low and middle-income countries, community health workers (CHWs) have the potential to provide support ... -
Poor retention does not have to be the rule: retention of volunteer community health workers in Uganda
(Health policy and planning, 2014)Globally, health worker shortages continue to plague developing countries. Community health workers are increasingly being promoted to extend primary health care to underserved populations. Since 2004, Healthy Child Uganda ... -
Outcomes of patients with severe sepsis after the first 6 hours of resuscitation at a regional referral hospital in Uganda
(Journal of Critical Care, 2016)Introduction: The optimal resuscitation strategy for patients with severe sepsis in resource-limited settings is unknown. Therefore, we determined the association between intravenous fluids, changes in vital signs and ... -
Mothers perception of blood transfusion in children under 5 years in Kisoro hospital, Uganda
(International Journal of Advanced Research, 2017)Introduction: Blood transfusion is the main cornerstones of modern medical practice which started way back in 1818 by James Brundell (Virge et al, 2000) and is the main treatment for anaemia. Although it is an important ... -
HIV-infected Ugandan women on antiretroviral therapy maintain HIV-1 RNA suppression across periconception, pregnancy, and postpartum periods
(Journal of acquired immune deficiency syndromes, 2016)Background: HIV-infected women risk sexual and perinatal HIV transmission during conception, pregnancy, childbirth, and breastfeeding. We compared HIV-1 RNA suppression and medication adherence across periconception, ... -
Evolving failures in the delivery of HIV care: Lessons from a Ugandan meningitis cohort 2006-2016
(In Open Forum Infectious Diseases, 2017)Background: Investments in HIV care in sub-Saharan Africa have increased the number of people aware of their status and receiving antiretroviral therapy (ART), yet HIV/AIDS mortality remains high. Methods: We performed ... -
Cyber-Senga: Ugandan youth preferences for content in an internet-delivered comprehensive sexuality education programme
(East African journal of public health, 2010-03)Globally more than 37 million people have been infected with the HIV virus. [1] Sub-Saharan Africa remains the region most heavily affected by HIV, accounting for 67% of all young people living with HIV and for 75% of AIDS ... -
Reuse of malaria rapid diagnostic tests for amplicon deep sequencing to estimate Plasmodium falciparum transmission intensity in western Uganda
(Scientific reports, 2018)Molecular techniques are not routinely employed for malaria surveillance, while cross-sectional, community-based parasite surveys require significant resources. Here, we describe a novel use of malaria rapid diagnostic ... -
Circumstances of child deaths in Mali and Uganda: a community-based confidential enquiry
(The Lancet Global Health, 2018)Background: Interventions to reduce child deaths in Africa have often underachieved, causing the Millennium Development Goal targets to be missed. We assessed whether a community enquiry into the circumstances of death ... -
Adolescents’ perceptions of sexual coercion in Uganda
(African Journal of AIDS Research, 2011)In Uganda, HIV prevalence remains high with young people at higher risk of infection than adults. Much is known about the sexual risk factors for HIV transmission among youths, including sexual encounters that are coerced. ...