Browsing Research Articles by Title
Now showing items 1-20 of 54
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Acute and sub-acute toxicity of Echinops kebericho decoction in rats
(BMC Complementary Medicine and Therapies, 2020)Background: Echinops kebericho is widely used for treatment of a variety of diseases including infectious, noninfectious disease and fumigation during child birth. Antibacterial, antimalarial, anti-leshimania, anti-diarrheal ... -
Acute and Sub-Acute Toxicity Study of Ethanolic Crude Extract of Mitracarpus hirtus Plant on Wistar Rats
(International Journal of Science and Healthcare Research, 2017)Background: Plants are still considered among the important source of bioactive compound, especially in traditional medicine that has been used for centuries. Ethno botanical survey showed that Mitracarpus hirtus is used ... -
African Progress in Drug Development Chemistry; a 100 Years Update
(2018)Africa is currently very active in the search for drugs particularly with focus on the preclinical phases of drug discovery. This work aimed at determining the extent to which Africa has gone with research and studies in ... -
The Analgesic and Antiplasmodial Activities and Toxicology of Vernonia amygdalina
(Journal of medicinal food, 2008)Vernonia amygdalina possesses several bioactive compounds and is used in traditional medicines of southwestern Uganda, along with other regions. Its analgesic potential has not been investigated thus far. The present study ... -
Analgesic, anti-inflammatory and oxytocic activities of Dracaena steudneri Engl. stem bark aqueous extract in Wistar rats
(Journal of Medicinal Plants Research, 2022-04)Dracaena steudneri Engl. (Dracaenaceae) is a medicinal plant that is used in labour by traditional birth attendants to induce labour, relieve pain and treat various diseases; albeit no documentation. This study determined ... -
Anti-fertility activity of aqueous root bark extracts of Asparagus africanus Lam and Annona senegalensis Pers combination on female Sprague Dawley rats
(African Journal of Pharmacy and Pharmacology, 2019)Many rural and poor women have now resorted to use of potential medicinal plants as a means of fertility control. Asparagus africanus Lam and Annona senegalensis Pers are some of the plants used for this purpose. The ... -
Antibacterial Activities of Echinops kebericho Mesfin Tuber Extracts and Isolation of the Most Active Compound, Dehydrocostus Lactone
(Frontiers in Pharmacology, 2021-01-25)Echinops kebericho Mesfin is traditionally used for the treatment of various infectious diseases. This study investigated antibacterial activity of the essential oil (EO) and the different fractions of ethanol extract. The ... -
Antifungal Activity of the Essential Oil of Echinops kebericho Mesfin: An In Vitro Study
(Evidence-Based Complementary and Alternative Medicine, 2020)Background: Echinops kebericho is an endemic medicinal plant in Ethiopia widely used in the treatment of infectious and noninfectious diseases. Essential oils are known for their antibacterial, antifungal, antiviral, ... -
Antimicrobial Bioactivity and GC-MS Analysis of Different Extracts of Corchorus olitorius L Leaves
(e Scientific World Journal, 2022-09-20)Plants have been used for the treatment of infectious diseases among various communities worldwide with undeniable success. Corchorus olitorius L is used to treat various ailments including infections. However, there are ... -
Antimicrobial Stewardship Programmes: Healthcare Providers’ Perspectives on Adopted Hospital Policies That Combat Antibacterial Resistance in Selected Health Facilities in Uganda
(Antibiotics, 2024)Background: This study aimed to determine healthcare providers’ perspectives on adopted hospital policies that support establishing antimicrobial stewardship programmes (ASPs) in selected health facilities in Uganda. ... -
Assessment of Bacterial Contamination and Antibiotic Susceptibility Patterns of Bacteria Isolated from Milk collected from Biharwe in Mbarara District: Cross-Sectional Study
(Journal of Veterinary Medicine and Surgery, 2022)Milk and dairy products are important source of vital nutrients for human beings. The unique composition and properties make milk an excellent medium for bacterial growth and source of bacterial infection. Milk borne ... -
Assessment of the immunomodulatory activity of Artavol® aqueous extract in Plasmodium berghei infected mice
(African Journal of Pharmacy and Pharmacology, 2022)ARTAVOL® is an herbal product derived from de-artemisinised extracts of Artemisia annua combined with lemon grass extract and avocado seed powder as a base locally used in Uganda for malaria prevention. This study assessed ... -
Assessment of the in vivo acute toxicity of aqueous extracts of artavol® antimalaria herbal tea
(African Journal of Pharmacy and Pharmacology, 2023)Acute toxicity testing plays a pivotal role in the initial safety assessment of products. It examines the effects of a single or multiple doses of a product administered to animals or taken by humans within a 24-hour period. ... -
Association of testosterone levels with socio-demographic characteristics in a sample of Ugandan men
(African Health Sciences, 2014)Background: Testosterone, a male reproductive hormone, affects several physiological processes, such as sperm production, energy, strength, sexual behavior, sleep and the general wellbeing of men. Normal levels of testosterone ... -
The availability of six tracer medicines in private medicine outlets in Uganda
(Journal of Pharmaceutical Policy and Practice, 2014)Objectives: Many low income countries struggle to provide safe and effective medicines due to poor public health care infrastructure, budgetary constraints, and lack of human resource capacity. Private sector pharmacies ... -
Barriers and facilitators to cognitive impairment screening among older adults with diabetes mellitus and hypertension by primary healthcare providers in rural Uganda
(Frontiers in Health Services, 2023-05-30)Background: The burden of non-communicable diseases and cognitive impairment exhibit a linear rise in sub-Saharan Africa due to the increase in life expectancy. Non-communicable diseases like diabetes mellitus and hypertension ... -
Chemical constituents and evidence-based pharmacological properties of Physalis peruviana L.: An overview
(Journal of Herbmed Pharmacology, 2021-01-21)Physalis peruviana L. is among plant species possessing evident nutritional, nutraceutical, and commercial interests. This review highlights the complexity of the chemical composition supporting the multiple pharmacotherapeutic ... -
Chronic khat (Catha edulis) and alcohol marginally alter complete blood counts, clinical chemistry, and testosterone in male rats
(Journal of Experimental Pharmacology, 2013)Introduction: Khat (Catha edulis) is a recreational psychoactive drug with psychostimulant properties. While the use of this drug is widespread in eastern Africa, including the Horn of Africa, surveys and anecdotal data ... -
A cross-sectional assessment of the effects of select training modalities on vaccine cold chain management
(Journal of Pharmaceutical Policy and Practice, 2024)Background: Vaccines offer arguably the most cost-effective public health intervention. Vaccine supply chain management which is a critical building block faces many Human resources challenges mainly due to the special ... -
Effects of Herbal Medicine Use on Adherence to Conventional Anticancer Drugs
(European Journal of Medicinal Plants, 2020)Background: Use of herbal medicines alongside conventional anticancer drugs is common among cancer patients. This may potentially cause reduced adherence to conventional anti-cancer drugs, unpredictable side effects and ...
