Research Articles: Recent submissions
Now showing items 21-40 of 54
-
Neural stem cell research in Africa: current realities and future prospects
(Biology Open, 2022)Neural stem cells (NSCs) are immature progenitor cells that are found in developing and adult brains that have the potential of dividing actively and renewing themselves, with a complex form of gene expression. The generation ... -
Evaluation of the effect of Artemisia Annua L. and Moringa Oleifera Lam. on CD4 count and viral load among PLWH on HAART at Mbarara Regional Referral Hospital: A Double-Blind Randomized Controlled Clinical Trial
(Research square, 2022)Background: Initiation of HAART among people living with HIV (PLWH) having a CD4 count ≤ 350cells/μl, produces poor immunological recovery, putting them at a high risk of opportunistic infections. Artemisia annua and Moringa ... -
Acute and Sub-Acute Toxicity Study of Ethanolic Crude Extract of Mitracarpus hirtus Plant on Wistar Rats
(International Journal of Science and Healthcare Research, 2017)Background: Plants are still considered among the important source of bioactive compound, especially in traditional medicine that has been used for centuries. Ethno botanical survey showed that Mitracarpus hirtus is used ... -
In vitro acaricidal activity of Azadirachta indica and Phytolacca dodecandra leaves and their combination on Rhipicephalus (boophilus) decoloratus
(J Med Herbs Ethnomed, 2022-09-27)Rhipicephalus (boophilus) decoloratus (ticks) are causing great economic loss among the cattle rearers from cattle mortalities and costs during the treatments. Synthetic acaricides have been used for a long time in the ... -
Registration, procurement, distribution, and use of misoprostol in Uganda: an interview-based observational study
(The Lancet, 2013)Background: Poor access to essential medicines remains a barrier to improvement of health in low-income countries. The maternal mortality rate from post-partum haemorrhage (PPH) in Uganda is one of the highest in the world. ... -
Factors associated with delayed onset of active labor following administration of vaginal Misoprostol among women at Mbarara Regional referral hospital, Uganda: A prospective cohort study
(Research square, 2019)Background: Vaginal misoprostol has been recommended by the World Health Organization as one of the effective methods for induction of labor. Globally 9.6% of all deliveries follow induction of labor. Although the goal of ... -
An Evaluation of Factors Affecting Drug Quality: Evidence from the Antimalarial Market in Uganda
(University of Massachusetts Boston, 2015-10-28)The quality of healthcare, and specifically medicines, is reportedly low in developing countries. We purchase and test 879 antimalarial drugs from 459 outlets in 44 randomly selected parishes (131 villages) in Uganda to ... -
Traditional uses of Corchorus olitorius L in Oyam District, Northern Uganda: A cross-sectional ethnobotanical survey
(Research square, 2020)Background: Corchorus olitorius L is a naturally growing green leafy vegetable used for various medicinal purposes worldwide. Several studies conducted elsewhere indicate that the plant is used for treating cardiac ... -
Traditional Medicinal Vegetables in Northern Uganda: An Ethnobotanical Survey
(International Journal of Food Science, 2021)Background: A wide range of indigenous vegetables grow in Uganda especially during rainy seasons but scarcely during droughts, except those that are commercially grown. Although a number of these vegetables have medicinal ... -
Seizure vulnerability and anxiety responses following chronic co-administration and acute withdrawal of caffeine and ethanol in a rat model
(Journal of Basic and Clinical Physiology and Pharmacology, 2018)Background: Caffeine antagonizes the intoxicating effects of alcohol. Consequently, there has been a dramatic global increase in the consumption of caffeinated drinks together with alcohol, especially among young adults. ... -
Safety and antidiarrheal activity of Priva adhaerens aqueous leaf extract in a murine model
(Journal of Ethnopharmacology, 2014)Ethnopharmacological relevance: Priva adhaerens (Forssk.) Chiov., a wildly growing plant, is reported in central Uganda to be. An effective traditional remedy for diarrhea. The objective of this study was to provide a ... -
Prevalence and factors associated with use of herbal medicine among women attending an infertility clinic in Uganda
(BMC Complementary and Alternative Medicine, 2014)Background: Infertility is a public health problem associated with devastating psychosocial consequences. In countries where infertility care is difficult to access, women turn to herbal medicines to achieve parenthood. ... -
Plants used to treat malaria in Nyakayojo sub-county, western Uganda
(Journal of Ethnopharmacology, 2011)Aim of study: We performed an ethnobotanical study of plants used to treat malaria in Nyakayojo subcounty in south western Uganda because malaria in this region, and in Uganda at large, is still the single most important ... -
Phytochemical Analysis, Acute Toxicity, as well as Antihyperglycemic and Antidiabetic Activities of Corchorus olitorius L. Leaf Extracts
(The Scientific World Journal, 2022)Background and Aim: Diabetes mellitus is a metabolic disorder that has no known cure with continuous endeavors to find a therapy for the condition. According to some studies, traditional leafy vegetables could prevent and ... -
Evaluation of the Acute and Sub chronic Toxicities of the Methanolic Stem Bark Extract of Spathodea campanulata (P. Beauv.) Bignoniaceae
(British Journal of Pharmacology and Toxicology, 2015)Spathodea campanulata (P. Beauv.) Bignoniacea is widely used in Ugandan traditional medicine without having much knowledge on any toxicity data. This study carried out the toxicity profile of its methanolic stem bark extract ... -
Association of testosterone levels with socio-demographic characteristics in a sample of Ugandan men
(African Health Sciences, 2014)Background: Testosterone, a male reproductive hormone, affects several physiological processes, such as sperm production, energy, strength, sexual behavior, sleep and the general wellbeing of men. Normal levels of testosterone ... -
Assessment of the immunomodulatory activity of Artavol® aqueous extract in Plasmodium berghei infected mice
(African Journal of Pharmacy and Pharmacology, 2022)ARTAVOL® is an herbal product derived from de-artemisinised extracts of Artemisia annua combined with lemon grass extract and avocado seed powder as a base locally used in Uganda for malaria prevention. This study assessed ... -
Antifungal Activity of the Essential Oil of Echinops kebericho Mesfin: An In Vitro Study
(Evidence-Based Complementary and Alternative Medicine, 2020)Background: Echinops kebericho is an endemic medicinal plant in Ethiopia widely used in the treatment of infectious and noninfectious diseases. Essential oils are known for their antibacterial, antifungal, antiviral, ... -
Analgesic, anti-inflammatory and oxytocic activities of Dracaena steudneri Engl. stem bark aqueous extract in Wistar rats
(Journal of Medicinal Plants Research, 2022-04)Dracaena steudneri Engl. (Dracaenaceae) is a medicinal plant that is used in labour by traditional birth attendants to induce labour, relieve pain and treat various diseases; albeit no documentation. This study determined ... -
Expression of cFos and brain‑derived neurotrophic factor in cortex and hippocampus of ethanol‑withdrawn male and female rats
(Journal of Pharmacology and Pharmacotherapeutics, 2013)Objective: To map areas of brain activation (cFos) alongside changes in levels of brain-derived neurotrophic factor (BDNF) to provide insights into neuronal mechanisms contributing to previously observed sex differences ...
