The relationship between HAART use and sexual activity among HIV-positive women of reproductive age in Brazil, South Africa, and Uganda
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Date
2008Author
Kaida, A.
Gray, G.
Bastos, F. I.
Andia, I.
Maier, M.
McIntyre, J.
Grinsztejn, B.
Strathdee, S. A.
Bangsberg, D. R.
Hogg, R.
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The purpose of this study was to determine whether current HAARTuse is associated with recent sexual intercourse among HIV-infected women (18_49 years) from Brazil, South Africa and Uganda. We conducted an analysis of survey data from a cross-sectional study, which enrolled 179 HIV-infected women receiving regular care from the Mbarara Hospital HIV Clinic in Uganda (n_85); the Perinatal HIV Research Unit in Soweto, South Africa (n_50); and the IPEC-Fiocruz cohort in Rio de Janeiro, Brazil (n_44). The primary outcome was sexual intercourse in the previous month. Secondary outcomes were protected sex and contraceptive use. We found that overall, 46% reported recent sexual intercourse. After adjusting for covariates, recent sexual intercourse was not associated with HAARTuse (AOR: 0.76; 95%CI: 0.34_1.72); however, it was
significantly associated with being currently married, wanting to have more children and having higher HAARToptimism. Among women reporting recent sexual intercourse (n_83), HAART users were significantly more likely to practice protected sex (crude OR: 3.64; 95%CI: 1.41_9.38) and non-significantly more likely to use contraceptive methods (crude OR: 2.15; 95%CI: 0.77_5.99). In summary, self-reported recent sexual intercourse is not more likely among women on HAART. Moreover, sexually active HAART users may be more likely to practice protected sex and use contraceptives.
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