Faculty of Medicine: Recent submissions
Now showing items 1181-1200 of 1992
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Risk factors for postpartum intrauterine device expulsion among women delivering at a tertiary Hospital in Uganda: a prospective cohort study
(Contraception and Reproductive Medicine, 2021)Background: Postpartum intrauterine device (PPIUD) use refers to intrauterine device (IUD) insertion after delivery but within 48 h of birth. In Uganda, the general use of modern methods of contraception is low with < 1% ... -
Placental decidual arteriopathy and vascular endothelial growth factor A (VEGF-A) expression among women with and without HIV
(The Journal of Infectious Diseases, 2021)Background: Women with HIV (WHIV) are at higher risk of adverse birth outcomes. Proposed mechanisms for the increased risk include placental arteriopathy (vasculopathy) and maternal vascular malperfusion (MVM) due to ... -
Implementing community-based human papillomavirus self-sampling with SMS text follow-up for cervical cancer screening in rural, southwestern Uganda
(Journal of Global Health, 2021)Background Self-collected HPV screening may improve cervical cancer screen¬ing coverage in low resource countries, yet data guiding implementation and fol¬low-up of abnormal results are sparse. Methods This is a prospective ... -
Chronic Placental Inflammation Among Women Living With HIV in Uganda
(ournal of Acquired Immune Deficiency Syndromes, 2020)Background: HIV-exposed, uninfected (HEU) children have poorer early-life outcomes than HIV-unexposed children. The determinants of adverse health outcomes among HEU children are poorly understood but may result from chronic ... -
Cesarean delivery in low- and middle-income countries: A review of quality of care metrics and targets for improvement
(Seminars in Fetal and Neonatal Medicine, 2021)Improving quality of care in low-and middle-income countries (LMICs) is a global priority, specifically around maternal and newborn care, where mortality and morbidity remain unacceptably high. Cesarean delivery is the ... -
Antenatal couples’ counselling in Uganda (ACCU): study protocol for a randomised controlled feasibility trial
(Pilot and Feasibility Studies, 2022)Background: Common avoidable factors leading to maternal, perinatal and neonatal deaths include lack of birth planning (and delivery in an inappropriate place) and unmet need for contraception. Progress has been slow because ... -
Altered Maternal Antibody Profiles in Women With Human Immunodeficiency Virus Drive Changes in Transplacental Antibody Transfer
(Clinical Infectious Diseases, 2022)Background: Human immunodeficiency virus (HIV)–exposed, uninfected (HEU) children have a higher risk of severe infection, but the causes are poorly understood. Emerging data point to altered antibody transfer in women with ... -
Post-discharge infections and healthcare contact in ugandan women hospitalized for delivery
(American Journal of Obstetrics & Gynecology, 2017)Objectives: Postpartum infection is a common cause of pregnancy related morbidity. Data are lacking from resource-limited settings on post-discharge febrile morbidity and healthcare contact in women with in-hospital ... -
Maternal anemia is associated with adverse obstetric, neonatal and placental outcomes in Mbarara, Uganda
(American Journal of Obstetrics & Gynecology, 2020)Objective: Maternal anemia is a significant risk factor for maternal morbidity and mortality, affecting 42% of pregnant women globally. In addition to increased risk of death from peripartum hemorrhage, anemic pregnant ... -
HIV Infection and risk of postpartum infection, complications and mortality in rural Uganda
(AIDS Care, 2018)HIV infection may increase risk of postpartum infection and infection-related mortality. We hypothesized that postpartum infection incidence and attributable mortality in Mbarara, Uganda would be higher in HIV-infected ... -
Cesarean delivery variation across facilities in Uganda
(American Journal of Obstetrics & Gynecolog, 2021-02)Objective: To describe caesarean delivery (CD) rates and their variability across health facilities and regions in Uganda. Study design: Using the 2018-2019 Ugandan Annual Health Sector Report, we extracted data on facility ... -
Molecular identification and anti‑malarial drug resistance profile of Plasmodium falciparum from patients attending Kisoro Hospital, southwestern Uganda
(Malaria Journal, 2022)Background: The evolution of malaria infection has necessitated the development of highly sensitive diagnostic assays, as well as the use of dried blood spots (DBS) as a potential source of deoxyribonucleic acid (DNA) yield ... -
Modified Plasma-Thrombin Method of Cell Block Preparation for Fine-Needle Aspiration Biopsies in Resource-Limited Settings
(American Journal of Clinical Pathology, 2018)Objectives: The plasma-thrombin method is commonly used to make cell blocks from fine-needle aspiration (FNA) samples but requires centrifugation. We describe a modification to this method that does not require centrifugation ... -
Maternal Attitudes about Objectively Monitored Bednet Use in Rural Uganda
(Malaria Research and Treatment, 2016)Insecticide-treated bednets (ITNs) are a mainstay of malaria prevention, yet poor adherence poses a major barrier to effective prevention. Self-reports of bednet use suffer from recall and social desirability biases. We ... -
Less Noise, More Hacking: How to Deploy Principles from MIT’s Hacking Medicine to Accelerate Health Care
(International Journal of Technology Assessment in Health Care, 2014)Medical technology offers enormous potential for scalable medicine to improve the quality and access in health care while simultaneously reducing cost. However, current medical device innovation within companies often only ... -
Knowledge and practices of women regarding prevention of mother-to-child transmission of HIV (PMTCT) in rural southwest Uganda
(International Journal of Infectious Diseases, 2013)Worldwide, about 3.4 million children aged under 15 years are HIV-infected, with 90% living in Sub-Saharan Africa;1 150 000 of these children are in Uganda. Ninety-five percent of pediatric HIV in Sub-Saharan Africa results ... -
Know Your Audience: Predictors of Success for a Patient-Centered Texting App to Augment Linkage to HIV Care in Rural Uganda
(Journal of medical Internet research, 2015)Background: Despite investments in infrastructure and evidence for high acceptability, few mHealth interventions have been implemented in sub-Saharan Africa. Objective: We sought to (1) identify predictors of uptake of ... -
Interpretation of tuberculin skin-test results in the diagnosis of tuberculosis in children
(African Health Sciences, 2005)Introduction: The tuberculin skin test is one of the most valuable tests for demonstrating tuberculous infection in both symptomatic and asymptomatic children. However, its application is often undermined by difficulties ... -
Induction of Rhizopus oryzae Germination Under Starvation Using Host Metabolites Increases Spore Susceptibility to Heat Stress
(Phytopathology, 2014)Sweetpotato is a nutritional source worldwide. Soft rot caused by Rhizopus spp. is a major limiting factor in the storage of produce, rendering it potentially unsafe for human consumption. In this study, Rhizopus oryzae ... -
Otomycosis among Patients Presenting with Ear Discharges at a Tertiary Hospital in South Western Uganda
(International Journal of tropical disease & Health, 2018)Aims: To the determine prevalence, mycology profile, associated symptoms and risk factors of otomycosis among patients that present with an ear discharge. Study Design: This was a cross-sectional study in which survey ...