Research Article: Recent submissions
Now showing items 41-60 of 136
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Variation of antioxidant and antibacterial activities of ethanolic extracts of propolis in three bee-keeping agro-ecological zones of Uganda
(African Journal of Pharmacy and Pharmacology, 2023)Propolis is a resinous plant material collected by bees to defend their colony. This study evaluated the antibacterial and antioxidant activities of ethanolic extracts of Ugandan propolis in three bee-keeping agro-ecological ... -
Microbial and physical evaluation of selected cough syrups sold at peripheral drug outlets in Bushenyi District, South Western Uganda
(African Journal of Pharmacy and Pharmacology, 2023)Syrups, being non-sterile liquid pharmaceutical formulations, are prone to microbial contamination. The most common microbial contaminants are bacteria and fungi. Contamination of oral liquid pharmaceuticals makes them ... -
Differences in Symptom Severity and Quality of Life among Patients with Cancer Using Conventional Therapies with/ without Herbal Medicines in Uganda: A Cross-Sectional Study
(Asian Pacific Journal of Cancer Prevention, 2023)Objective: Patients with cancer experience numerous symptoms related to cancer and treatment side effects that reduce their quality of life (QOL). Although herbal medicine (HM) is used to manage such symptoms by patients ... -
Application of the herbal chemical marker ranking system (Herb MaRS) to the standardization of herbal raw materials: a case study
(BMC Complementary Medicine and Therapies, 2023)Introduction: Phytochemical standardization of herbal materials involves establishing consistent levels of one or more active ingredients or markers. It ensures the authenticity and quality of herbal materials, extracts, ... -
Suberosin Alleviates Thiazolidinedione‑Induced Cardiomyopathy in Diabetic Rats by Inhibiting Ferroptosis via Modulation of ACSL4‑LPCAT3 and PI3K‑AKT Signaling Pathways
(Cardiovascular Toxicology, 2023)Thiazolidinediones are useful antidiabetic medications. However, their use is associated with adverse side effects like edema, heart failure and bone fractures. In this study, we investigated the anti-ferroptosis effects ... -
Anti-ageing Activity and Antioxidant Activity of Methanol Extracts of Leaves and Flowers of Salvia officinalis and Rosmarinus officinalis
(Journal of Young Pharmacists, 2023)Background: In this present work, methanol extracts of the leaves and flowers of Salvia officinalis Linn. (MES) and Rosmarinus officinalis Linn. (MER) were examined for their potential anti-aging and antioxidant properties ... -
Frequency, severity, and factors associated with clinically significant drug‑drug interactions among patients with cancer attending Mbarara Regional Referral Hospital Cancer Unit, Uganda
(BMC cancer, 2022)Background: Cancer is a major public health problem with pharmacotherapy being the cornerstone of its management. Cancer patients receive multiple drugs concurrently risking Drug-Drug Interactions (DDIs). DDIs, though ... -
The meaning of caring for patients with cancer among traditional medicine practitioners in Uganda: A grounded theory approach
(PLOS Global Public Health, 2023)Traditional medicine practitioners (TMPs) are a critical part of healthcare systems in many sub-Saharan African countries and play vital roles in caring for patients with cancer. Despite some progress in describing TMPs’ ... -
Ligand-protein interactions of plant-isolated (9z,12z)-octadeca-9,12-dienoic acid with B-ketoacyl-Acp synthase (KasA) in potential anti-tubercular drug designing
(Scientific African, 2020)Mycobacterium tuberculosis remains one of the world’s contributors to mortality. With the emergence of SARS-CoV-2 coinfections, patients with TB are predisposed to being more heavily weighed down by COVID-19 disease and ... -
Evaluating the Feasibility, Acceptability, and Preliminary Efficacy of SupportMoms-Uganda, an mHealth-Based Patient-Centered Social Support Intervention to Improve the Use of Maternity Services Among Pregnant Women in Rural Southwestern Uganda: Randomized Controlled Trial
(JMIR Formative Research, 2023)Background: SMS text messaging and other mobile health (mHealth) interventions may improve knowledge transfer, strengthen access to social support (SS), and promote positive health behaviors among women in the perinatal ... -
Ethnobotanical Survey of Medicinal Plants Used in Breast Cancer Treatment by Traditional Health Practitioners in Central Uganda
(Journal of Multidisciplinary Healthcare, 2023)Purpose: The study aimed to document the existing knowledge and practices related to breast cancer recognition and treatment using medicinal plants by traditional health practitioners in Central Uganda. Methods: This ... -
Review of Deforestation in Ugandan Tropical Rainforest Reserves: A Threat to Natural Medicine
(East African Journal of Environment and Natural Resources, 2022)Deforestation in Ugandan Tropical Rainforest Reserves as threat to natural medicine is still undocumented. In this study, we reviewed literature on deforestation most especially from 1990-2020 in the Tropical Rainforest ... -
In-vitro antihelminthic activity of alcoholic extract from Paullinia pinnata Linn against Ascaris suum
(Revista Cubana de Plantas Medicinales, 2018)Introduction: Medicinal plants are used both for the treatment of certain conditions and to preserve health and vitality. According to estimates by the World Health Organization, 80% of the world population, excluding ... -
Identification of Antimicrobial Peptides Isolated From the Skin Mucus of African Catfish, Clarias gariepinus (Burchell, 1822)
(Frontiers in microbiology, 2021)Antimicrobial peptides (AMPs) constitute a broad range of bioactive compounds in diverse organisms, including fish. They are effector molecules for the innate immune response, against pathogens, tissue damage and infections. ... -
Evaluation of Cafeteria Diet in Experimental Animal with Plant Extract of Calotropis procera for Obesity Parameter
(Journal for Research in Applied Sciences and Biotechnology, 2022)The function of obesity in an insulin-resistant syndrome associated with hyper insulinemia, hypertension, hyperlipidemia, atherosclerotic diseased illness is vital. Hunger, body weight and lipid profile investigations thus ... -
Traditional Approaches and Medicinal Plants in Treatment of Epilepsy in West and East Africa
(NeuroPharmac Journal, 2020)Background: Epilepsy has affected over sixty million people around the globe. Traditionally, communities have opted for complementary and alternative medicines (CAM) to help in the treatment of epilepsy which has worked ... -
Pharmacognostic and phytochemical studies as an invaluable approach for correct identification of medicinal plants: The case of Artemisia vulgaris L. substituted for Artemisia annua L. in Western Uganda
(TMR Integrative Medicine, 2023)Different parts of Artemisia vulgaris L. (A. vulgaris) are ethno-medicinally used as an emmenagogue and for the treatment of ailments such as malaria fever, ulcers, and cancer. However, anecdotal evidence shows that the ... -
Retrospective in silico mutation profiling of SARS-CoV-2 structural proteins circulating in Uganda by July 2021: Towards refinement of COVID-19 disease vaccines, diagnostics, and therapeutics
(Plos one, 2022)The SARS-CoV-2 virus, the agent of COVID-19, caused unprecedented loss of lives and economic decline worldwide. Although the introduction of public health measures, vaccines, diagnostics, and therapeutics disrupted the ... -
Association between Pre-Hospital Antibiotic Exposure and Level of Bacterial Resistance (PHAE Study): A Matched Case Control Study at the Medical and Paediatric wards of Mbarara Regional Referral Hospital-South Western Uganda
(Research square, 2022-09-07)Background: This study aimed to determine the association between pre-hospital antibiotic exposure and level of bacterial resistance among adult and paediatric patients. Methods: In the study, 79 antibiotic pre-exposed ... -
Ligand-protein interactions of plant-isolated (9z,12z)-octadeca-9,12-dienoic acid with B-ketoacyl-Acp synthase (KasA) in potential anti-tubercular drug designing
(Scientific African, 2021)Mycobacterium tuberculosis remains one of the world’s contributors to mortality. With the emergence of SARS-CoV-2 coinfections, patients with TB are predisposed to being more heavily weighed down by COVID-19 disease and ...