Browsing Research Articles by Title
Now showing items 1-20 of 91
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AmpC-BETA Lactamases among Enterobacteriaceae Isolated at a Tertiary Hospital, South Western Uganda
(British biotechnology journal, 2014)Aim—To characterize AmpC-beta lactamases among Enterobacteriaceae isolates from clinical samples at Mbarara Regional Referral Hospital. Study Design—Laboratory-based descriptive cross-sectional study Place and Duration ... -
Anti-Mycobacterial Activity of Medicinal Plant Extracts Used in the Treatment of Tuberculosis by Traditional Medicine Practitioners in Uganda
(Pharmacology & Pharmacy, 2023)Tuberculosis (TB) remains a public health challenge and one of the leading causes of death worldwide. TB is preventable and curable. However, treatment of tuberculosis has continued to be difficult as a result of rapid ... -
Antifungal Susceptibility Patterns of Vulvovaginal Candida species among Women Attending Antenatal Clinic at Mbarara Regional Referral Hospital, South Western Uganda
(British microbiology research journal, 2015)Aims—To identify the Candida species that cause vulvovaginal candidiasis and determine their antifungal susceptibility patterns. Study Design—This was a cross-sectional study. Place and Duration of Study—The study was ... -
Antimicrobial resistance at the human–animal interface in the Pastoralist Communities of Kasese District, South Western Uganda
(Scientific Reports, 2020-09-07)Intensive usage of antimicrobials in the management of animal diseases leads to selection for resistance among microorganisms. This study aimed to assess antimicrobial use and to describe factors associated with the ... -
Antimicrobial Resistance of Neisseria gonorrhoeae Isolated from Out Patients Presenting with Urethral and Vaginal Discharges at Mbarara Regional Referral Hospital
(Journal of Advances in Medicine and Medical Research, 2019-08-16)Background: Gonococcus is one of the most common sexually transmitted diseases in developing countries and it has become a global health burden, hence a need for effective treatment. However, there is growing trend of ... -
Antimicrobial Resistance Patterns and Molecular Characterization of Klebsiella pneumoniae in Clinical Isolates at Mbarara Regional Referral Hospital
(Advances in Infectious Diseases, 2019-08)Background: Klebsiella pneumoniae is one of the most frequent opportunistic pathogens causing a range of infections and being resistant for beta- lactamases (ESBL) and Carbapenemases. Aim: The aim of the present study ... -
Antimicrobial resistance profile among bacteria isolated from patients presenting with wounds at Kabale Regional Referral Hospital, South western Uganda
(Research square, 2020)Background: Bacterial Wound infection and antimicrobial resistance remains a public health challenge. The challenge remains worse due to nosocomial bacterial infection often characterized by multidrug resistance. Infected ... -
Assessment of Pathogenic Contamination and Antimicrobial Activity of Selected Herbal Medicinal Remedies in Mbarara City, South Western Uganda
(Research square, 2021)Background: Herbal formulations in Mbarara have been used in the treatment and management of several disease conditions extensively overtime due to low cost compared to empirical synthetic medicine, however evidenced that ... -
Bacterial Contamination of Blood and Blood Products at Mbarara Regional Blood Bank in Rural South Western Uganda
(Advances in Infectious Diseases, 2013-09)Background: Screening blood donors has practically eliminated viral and bacterial pathogens in blood used for trans- fusion. However, transfusion-associated bacterial sepsis remains an important health-care concern and the ... -
Bacteriological profile, antibiotic susceptibility and factors associated with neonatal Septicaemia at Kilembe mines hospital, Kasese District Western Uganda
(BMC microbiology, 2021)Introduction: Neonatal septicaemia is one of the most common leading causes of neonatal morbidity and mortality in developing countries. It is estimated to affect more than 30 million people worldwide annually, potentially ... -
Chromatographic, Mass and Cytotoxicity analysis of Isolates from Eichhornia crassipes’ Roots and Leaves against HepG2 and MCF7 cell lines
(Cogent Biology, 2021-01-29)Cancers remain one of the leading causes of death in the world. However, known conventional cancer medicines remain scarce, expensive and out of reach to many patients. To provide an alternative for the expensive therapies, ... -
Clindamycin Resistance among Methicillin Resistant Staphylococcus aureus Isolated from Human and Respective Household Swine in Greater Kabale Region—South Western Uganda
(Advances in Infectious Diseases, 2019-12-12)Introduction: S. aureus is recognized as the common cause of nosocomial and community-acquired infections. Macrolide-Lincosamide-Streptogramin B (MLSB) is thought to be alternative therapies against MRSA infections. ... -
Clindamycin Resistance among Staphylococcus Aureus Isolated at Mbarara Regional Referral Hospital, in South Western Uganda
(2014-12)Aims—The study was conducted to determine the prevalence of Clindamycin (CL) resistance and antimicrobial susceptibility among clinical isolates of Staphylococcus aureus (S. aureus) from Mbarara Regional Referral Hospital ... -
Clinical Conditions of Hospitalized Older Adult Patients and Their Outcomes in a Regional Referral Hospital in Southwestern Uganda
(Journal of Aging Research, 2019-06-29)Background. Recent advances in medicine have caused positive impact on the life expectancy of most countries, resulting in increased older adult population. Aging comes with a number of health challenges. (is study ... -
Comparison of patient length of stay in care between homebased care and hospitalized covid-19 patients in northern and West Nile regions, Uganda
(Research square, 2023)SARS-CoV-2-caused COVID-19 was first detected in Wuhan, China, in December 2019. Uganda reported her first COVID-19 case on March 21, 2020. The pandemic placed an enormous burden on health systems across the world. This ... -
Cryptococcus neoformans Genotypic Diversity and Disease Outcome among HIV Patients in Africa
(Journal of Fungi, 2022)Cryptococcal meningoencephalitis, a disease with poor patient outcomes, remains the most prevalent invasive fungal infection worldwide, accounting for approximately 180,000 deaths each year. In several areas of sub-Saharan ... -
Detection and Quantification of Mycobacterium tuberculosis in the Sputum of Culture-Negative HIV-infected Pulmonary Tuberculosis Suspects: A Proof-of-Concept Study
(PLoS ONE, 2016)Rationale: Rapid diagnosis of pulmonary tuberculosis (TB) is critical for timely initiation of treatment and interruption of transmission. Yet, despite recent advances, many patients remain undiagnosed. Culture, usually ... -
Detection of Plasmodium Species by High-Resolution Melt Analysis of DNA from Blood Smears Acquired in Southwestern Uganda
(Journal of Clinical Microbiology, 2017-10-02)Microscopic diagnosis of malaria using Giemsa-stained blood smears is the standard of care in resource-limited settings. These smears represent a potential source of DNA for PCR testing to confirm Plasmodium infections or ... -
Diagnosis of Tuberculosis in a High TB-HIV Environment Using Microscopy and Culture-the Example of Kakiika Prison-Kyamugorani, Mbarara, Uganda
(Journal of Science and Technology, 2016)There is growing concern about the high transmission of tuberculosis (TB) in prisons posing a risk to the outside community. There are high levels of overcrowding in the Uganda Prisons Service (UPS) with some prisons ...