Browsing Research Articles by Issue Date
Now showing items 1-20 of 103
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Lowenstein-Jensen Selective Medium for Reducing Contamination in Mycobacterium tuberculosis Culture
(JCM, 214-07)We compared Mycobacterium tuberculosis sputum culture recovery and contamination rates between Lowenstein-Jensenmedium(LJ)containing the following decontaminants and LJalone:(i)PANTA(n 299),(ii) Selectatab-MB(n 299),and(iii) ... -
Dose Response Effect of High-Dose Fluconazole for HIV-Associated Cryptococcal Meningitis in Southwestern Uganda
(Clinical infectious diseases, 2008)Background. Therapy for human immunodeficiency virus (HIV)–associated cryptococcal meningitis in many centers in Africa is fluconazole administered at a dosage of 400–800 mg per day. However, higher dosages of fluconazole ... -
Genetic diversity of Mycobacterium tuberculosis in Mbarara, South Western Uganda
(African health sciences, 2010)Background: We determined the genetic diversity of mycobacteria isolated from tuberculosis patients in Mbarara Uganda, using region of difference (RD) analysis and spacer oligonucleotide typing (spoligotyping). Methods: ... -
Use of the GenoType® MTBDRplus assay to assess drug resistance of Mycobacterium tuberculosis isolates from patients in rural Uganda
(BMC clinical pathology, 2010-08-06)Background: Drug resistance levels and patterns among Mycobacterium tuberculosis isolates from newly diagnosed and previously treated tuberculosis patients in Mbarara Uganda were investigated. Methods: We enrolled, ... -
Regional Anthropometry Changes in Antiretroviral-Naı¨ve Persons Initiating a Zidovudine-Containing Regimen in Mbarara, Uganda
(AIDS research and human retroviruses, 2011)Lipodystrophy is commonly reported in Africa after antiretroviral therapy (ART) is initiated, but few studies have objectively measured changes in body composition. Body composition was determined in 76 HIV-infected ... -
Mycobacterium tuberculosis spoligotypes and drug susceptibility pattern of isolates from tuberculosis patients in South-Western Uganda
(BMC Infectious Diseases, 2011-03-31)Background: Determination of the prevalence and drug susceptibility of the M. tuberculosis strains is important in tuberculosis control. We determined the genetic diversity and susceptibility profiles of mycobacteria ... -
Malaria is an uncommon cause of adult sepsis in south-western Uganda
(Malaria Journal, 2013-05-01)Background: Malaria is often considered a cause of adult sepsis in malaria endemic areas. However, diagnostic limitations can make distinction between malaria and other infections challenging. Therefore, the objective of ... -
Bacterial Contamination of Blood and Blood Products at Mbarara Regional Blood Bank in Rural South Western Uganda
(Advances in Infectious Diseases, 2013-09)Background: Screening blood donors has practically eliminated viral and bacterial pathogens in blood used for trans- fusion. However, transfusion-associated bacterial sepsis remains an important health-care concern and the ... -
AmpC-BETA Lactamases among Enterobacteriaceae Isolated at a Tertiary Hospital, South Western Uganda
(British biotechnology journal, 2014)Aim—To characterize AmpC-beta lactamases among Enterobacteriaceae isolates from clinical samples at Mbarara Regional Referral Hospital. Study Design—Laboratory-based descriptive cross-sectional study Place and Duration ... -
Trends in Antimicrobial Resistance of Staphylococcus aureus Isolated from Clinical Samples at Mbarara Regional Referral Hospital in Rural Uganda
(British Microbiology Research Journal, 2014)Aim: This study aimed at describing the antibiotic susceptibility patterns of S. aureus isolated from clinical samples at Mbarara Regional Referral Hospital from 2003 to 2012. Methods: This was a retrospective study that ... -
Prevalence and antibiotic susceptibility patterns of clinical isolates of methicillin- resistant staphylococcus aureus in a tertiary care hospital in western Uganda
(British Microbiology Research Journal, 2014-06-30)Aim: To determine the prevalence and antibiotic susceptibility patterns of clinical isolates of methicillin resistant Staphylococcus aureus isolated at Mbarara Regional Referral Hospital. Method: A total of 400 S. aureus ... -
Clindamycin Resistance among Staphylococcus Aureus Isolated at Mbarara Regional Referral Hospital, in South Western Uganda
(2014-12)Aims—The study was conducted to determine the prevalence of Clindamycin (CL) resistance and antimicrobial susceptibility among clinical isolates of Staphylococcus aureus (S. aureus) from Mbarara Regional Referral Hospital ... -
Prevalence and genotypic characterization of extended spectrum beta-lactamases produced by gram negative bacilli at a tertiary care hospital in rural south western Uganda.
(2014-12)Aim To determine the prevalence and genotypic characterisation of extended spectrum beta-lactamases produced by gram negative bacilli isolated at Mbarara Regional Referral Hospital (MRRH). Samples Gram negative clinical ... -
Antifungal Susceptibility Patterns of Vulvovaginal Candida species among Women Attending Antenatal Clinic at Mbarara Regional Referral Hospital, South Western Uganda
(British microbiology research journal, 2015)Aims—To identify the Candida species that cause vulvovaginal candidiasis and determine their antifungal susceptibility patterns. Study Design—This was a cross-sectional study. Place and Duration of Study—The study was ... -
Health-point survey of bacteria urinary tract infections among suspected diabetic patients attending clinics in Bushenyi, Uganda
(Special Bacteria Pathogens Journal (SBPJ), 2015)Background: Although Urinary tract infections (UTI) and diabetes are individual public health pandemic, their comorbidities remain a global health dilemma. Regional surveillance holds the key to effective intervention. ... -
Feasibility for Same Day Tuberculosis Diagnosis Using the Smear Microscopy Approach in Rural South Western Uganda
(Advances in Research, 2015)Background: WHO recently recommended the collection of two sputum smears and that these specimens can be collected in an accelerated scheme called front-loaded or same-day microscopy. We studied the feasibility of same ... -
Task Shifting and Skin Punch for the Histologic Diagnosis of Kaposi’s Sarcoma in Sub-Saharan Africa: A Public Health Solution to a Public Health Problem
(Oncology, 2015)Fueled by HIV, sub-Saharan Africa has the highest incidence of Kaposi’s sarcoma (KS) in the world. Despite this, KS diagnosis in the region is based mostly on clinical grounds. Where biopsy is available, it has traditionally ... -
Nasopharyngyeal Carriage and Antimicrobial Susceptibility of Streptococcus pneumoniae, in Children under Five Years at Mbarara Regional Referral Hospital, Uganda
(International journal of tropical disease & health, 2015-01-21)Background: Acute respiratory infections (ARI) are a leading cause of childhood morbidity and mortality, causing 25-30% of all deaths in developing countries. Pneumococcal disease is a significant public health problem ... -
Low Resistance to First and Second Line Anti- Tuberculosis Drugs among Treatment Naive Pulmonary Tuberculosis Patients in Southwestern Uganda
(PLoS ONE, 2015-02-06)Background: There are limited data on region-specific drug susceptibility of tuberculosis (TB) in Uganda. We performed resistance testing on specimens collected from treatment-naive patients with to provide data to guide ... -
Prevalence and Economic Impact of Bovine Fasciolosis at Kampala City Abattoir, Central Uganda
(British Microbiology Research Journal, 2015-03-13)Aim: This study was carried out to determine the prevalence of bovine fasciolosis in indigenous cattle slaughtered in Kampala City abattoir and to compare the diagnostic efficiency of fecal and post mortem examination. The ...
