Research Articles: Recent submissions
Now showing items 21-40 of 103
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Treatment seeking and antibiotic use for urinary tract infection symptoms in the time of COVID-19 in Tanzania and Uganda
(Journal of Global Health, 2024)Background: There is still little empirical evidence on how the outbreak of coronavirus disease 2019 (COVID-19) and associated regulations may have disrupted care-seeking for non-COVID-19 conditions or affected antibiotic ... -
The ‘indirect costs’ of underfunding foreign partners in global health research: A case study
(Global Public Health, 2017)This study of a global health research partnership assesses how U.S. fiscal administrative policies impact capacity building at foreign partner institutions. We conducted a case study of a research collaboration between ... -
Klebsiella pneumoniae carbapenamases in Escherichia coli isolated from humans and livestock in rural south-western Uganda
(PLoS ONE, 2023)Background: The accumulation of resistance genes in Escherichia coli (E. coli) strains imposes limitations in the therapeutic options available for the treatment of infections caused by E. coli. Production of Klebsiella ... -
Paenibacillus spp infection among infants with postinfectious hydrocephalus in Uganda: an observational case-control study
(The Lancet Microbe, 2023)Background: Paenibacillus thiaminolyticus is a cause of postinfectious hydrocephalus among Ugandan infants. To determine whether Paenibacillus spp is a pathogen in neonatal sepsis, meningitis, and postinfectious hydrocephalus, ... -
Cryptococcus neoformans Genotypic Diversity and Disease Outcome among HIV Patients in Africa
(Journal of Fungi, 2022)Cryptococcal meningoencephalitis, a disease with poor patient outcomes, remains the most prevalent invasive fungal infection worldwide, accounting for approximately 180,000 deaths each year. In several areas of sub-Saharan ... -
Comparison of patient length of stay in care between homebased care and hospitalized covid-19 patients in northern and West Nile regions, Uganda
(Research square, 2023)SARS-CoV-2-caused COVID-19 was first detected in Wuhan, China, in December 2019. Uganda reported her first COVID-19 case on March 21, 2020. The pandemic placed an enormous burden on health systems across the world. This ... -
Prevalence of Nasal Carriage of Methicillin Resistant Staphylococcus aureus among Patients, Health Care Workers and Patients’ Care Takers at Kabale Regional Referral Hospital, South Western Uganda
(Research square, 2023)Background: Methicillin Resistant Staphylococcus aureus (MRSA) is a type of Gram-positive bacterium that is genetically different from other strains of Staphylococcus aureus by virtue its capability to overcome the actions ... -
Umbilical Stump Colonization and Antibiotic Susceptibility Patterns of Bacteria from Umbilical Stumps of Neonates Admitted at Holy Innocents Children’s Hospital, Mbarara, South Western Uganda
(Research square, 2023)Introduction: Every year a million deaths of neonates occur worldwide due to bacteria that has ascended through the umbilical stump leading to serious infection. An umbilical stump that has just separated is known to be ... -
Undergraduate Learning in the COVID-19 Pandemic: Lessons Learned and Ways Forward
(Advances in Medical Education and Practice, 2023)The SARS-CoV-2 coronavirus (COVID-19) pandemic is in constant evolution, much like the virus, and we must learn to adapt our undergraduate education and learning strategies to enable students to complete their studies. ... -
Anti-Mycobacterial Activity of Medicinal Plant Extracts Used in the Treatment of Tuberculosis by Traditional Medicine Practitioners in Uganda
(Pharmacology & Pharmacy, 2023)Tuberculosis (TB) remains a public health challenge and one of the leading causes of death worldwide. TB is preventable and curable. However, treatment of tuberculosis has continued to be difficult as a result of rapid ... -
MinION Whole-Genome Sequencing in Resource-Limited Settings: Challenges and Opportunities
(Current Clinical Microbiology Reports, 2022-11)Purpose of Review The introduction of MinION whole-genome sequencing technology greatly increased and simplified complete genome sequencing in various fields of science across the globe. Sequences have been generated from ... -
Factors Associated With Medical Students’ Career Choices Regarding Internal Medicine In Uganda
(Advances in Medical Education and Practice, 2022-10-14)Background: There is an unmet need for internal medicine physicians in Uganda owing to the growing burden of diseases. This study aimed at evaluating the factors associated with career choices of undergraduate medical ... -
Prevalence of Helicobacter pylori among Patients with Gastrointestinal Tract (GIT) Symptoms: A Retrospective Study at Selected Africa Air Rescue (AAR)Clinics in Kampala, Uganda, from 2015 to 2019
(Journal of Tropical Medicine, 2021)Background: Helicobacter pylori (HP) infection is extremely common worldwide, with almost half of the world’s population infected. In Uganda, no study has been done on the trends of the prevalence of H. pylori infection ... -
Unmasking Higher-than-Expected Prevalence of Mycobacterium tuberculosis DNA in Respiratory Samples from US born Patients in a Safety Net Hospital in Boston.
(2020)The recent description of sequential inflammatory stages characterizing early tuberculosis (TB) disease and reports of disease caused by differentially culturable M. tuberculosis have significantly complicated the diagnostic ... -
Diagnosis of Tuberculosis in a High TB-HIV Environment Using Microscopy and Culture-the Example of Kakiika Prison-Kyamugorani, Mbarara, Uganda
(Journal of Science and Technology, 2016)There is growing concern about the high transmission of tuberculosis (TB) in prisons posing a risk to the outside community. There are high levels of overcrowding in the Uganda Prisons Service (UPS) with some prisons ... -
Incidence and Etiology of Catheter Associated Urinary Tract Infection among Admitted Patients at Kabale Regional Referral Hospital, South Western Uganda
(Advances in Infectious Diseases, 2019)Introduction: Catheter Associated Urinary Tract Infection is the most common hospital acquired infection worldwide. Urinary Tract Infections among catheterised patients are on rise regardless of antibiotic use and this is ... -
Further evidence of Mycobacterium tuberculosis in the sputum of culture negative pulmonary tuberculosis suspects using an ultrasensitive molecular assay
(Tuberculosis, 2019)Background: Rapid diagnosis of pulmonary tuberculosis (TB) is critical to TB control. However, many patients with paucibacillary TB disease remain undiagnosed. Current TB elimination goals require new tools to diagnose ... -
Detection and Quantification of Mycobacterium tuberculosis in the Sputum of Culture-Negative HIV-infected Pulmonary Tuberculosis Suspects: A Proof-of-Concept Study
(PLoS ONE, 2016)Rationale: Rapid diagnosis of pulmonary tuberculosis (TB) is critical for timely initiation of treatment and interruption of transmission. Yet, despite recent advances, many patients remain undiagnosed. Culture, usually ... -
Unravelling patient pathways in the context of antibacterial resistance in East Africa
(Research square, 2022)Background: A key factor driving the development and maintenance of antibacterial resistance (ABR) is individuals’ use of antibiotics (ABs) to treat illness. It is therefore crucial to understand the dynamics of patient ... -
Good Utilization, Low Completion Rates of Early Infant HIV Diagnostic Services at a District Hospital in Rural South Western Uganda
(Research square, 2022-03-02)Introduction: Early Infant Diagnosis (EID) using DNA PCR has been utilized in the diagnosis of HIV worldwide. This study aimed to determine the utilization of EID using DNA PCR. Methods: A mixed methods study involving ...
